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The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis.

1. J Sex Med. 2019 Feb;16(2):223-234. doi: 10.1016/j.jsxm.2018.12.002. The Potential Role of Arginine Supplements on Erectile Dysfunction: A Systemic Review and Meta-Analysis. Rhim HC(1), Kim MS(1), Park YJ(2), Choi WS(2), Park HK(2), Kim HG(2), Kim A(2), Paick SH(3). Author information: (1)Kor

Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus.

2. Cochrane Database Syst Rev. 2005 Jan 25;2005(1):CD004096. doi: 10.1002/14651858.CD004096.pub2. Pharmacotherapy for weight loss in adults with type 2 diabetes mellitus. Norris SL(1), Zhang X, Avenell A, Gregg E, Schmid CH, Lau J. Author information: (1)Division of Diabetes Translation, Nationa

Dissociable glucocorticoid and noradrenergic effects on parochial cooperation and competition in intergroup conflict.

3. Proc Natl Acad Sci U S A. 2025 Jul 22;122(29):e2502257122. doi: 10.1073/pnas.2502257122. Epub 2025 Jul 14. Dissociable glucocorticoid and noradrenergic effects on parochial cooperation and competition in intergroup conflict. Dashti D(#)(1)(2), Lüpken LM(#)(1), Seidisarouei M(1), Forbes PAG(1)

Effects of stress-related neuromodulators on amygdala and hippocampus resting state functional connectivity.

4. J Psychopharmacol. 2024 Jul;38(7):604-614. doi: 10.1177/02698811241260972. Epub 2024 Jun 20. Effects of stress-related neuromodulators on amygdala and hippocampus resting state functional connectivity. Rosada C(1), Lipka R(1)(2), Metz S(1)(3), Otte C(1)(4), Heekeren H(5), Wingenfeld K(1)(4).

The effects of yohimbine and hydrocortisone on selective attention to fearful faces: An fMRI study.

5. Psychoneuroendocrinology. 2024 Jul;165:107031. doi: 10.1016/j.psyneuen.2024.107031. Epub 2024 Mar 21. The effects of yohimbine and hydrocortisone on selective attention to fearful faces: An fMRI study. Metz S(1), Mengering L(2), Lipka R(3), Rosada C(2), Otte C(2), Heekeren H(4), Wingenfeld K

No changes in triple network engagement following (combined) noradrenergic and glucocorticoid stimulation in healthy men.

6. Soc Cogn Affect Neurosci. 2024 Jan 4;19(1):nsad073. doi: 10.1093/scan/nsad073. No changes in triple network engagement following (combined) noradrenergic and glucocorticoid stimulation in healthy men. Lipka R(1)(2), Rosada C(1), Metz S(1)(3), Hellmann-Regen J(1), Heekeren H(4), Wingenfeld K(1

Evaluation of Hydroxychloroquine as a Perpetrator on Cytochrome P450 (CYP) 3A and CYP2D6 Activity with Microdosed Probe Drugs in Healthy Volunteers.

7. Eur J Drug Metab Pharmacokinet. 2024 Jan;49(1):101-109. doi: 10.1007/s13318-023-00872-2. Epub 2023 Dec 20. Evaluation of Hydroxychloroquine as a Perpetrator on Cytochrome P450 (CYP) 3A and CYP2D6 Activity with Microdosed Probe Drugs in Healthy Volunteers. Stoll F(1), Blank A(2), Mikus G(2), C

Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study.

8. Addict Biol. 2023 Jul;28(7):e13288. doi: 10.1111/adb.13288. Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Haass-Koffler CL(1)(2)(3)(4), Magill M(1)(3), Cannella N(5), Brown JC(6), Aoun EG(7), Cioe PA(1)(3), Sinha R(8), Swift RM(1)

The effects of hydrocortisone and yohimbine on human behavior in approach-avoidance conflicts.

9. Psychopharmacology (Berl). 2023 Aug;240(8):1705-1717. doi: 10.1007/s00213-023-06396-6. Epub 2023 Jun 14. The effects of hydrocortisone and yohimbine on human behavior in approach-avoidance conflicts. Fricke K(1)(2), Alexander N(3), Jacobsen T(4), Krug H(5), Wehkamp K(5), Vogel S(6)(7). Auth

Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear.

10. Int J Neuropsychopharmacol. 2022 Sep 28;25(9):759-773. doi: 10.1093/ijnp/pyac038. Alpha-2 Adrenoreceptor Antagonist Yohimbine Potentiates Consolidation of Conditioned Fear. Sperl MFJ(1)(2)(3), Panitz C(1)(4)(5), Skoluda N(6), Nater UM(6), Pizzagalli DA(3), Hermann C(2), Mueller EM(1). Auth

Comparison of TWA and PEP as indices of α2- and ß-adrenergic activation.

11. Psychopharmacology (Berl). 2022 Jul;239(7):2277-2288. doi: 10.1007/s00213-022-06114-8. Epub 2022 Apr 8. Comparison of TWA and PEP as indices of α2- and ß-adrenergic activation. Drost L(1), Finke JB(2), Port J(3), Schächinger H(4). Author information: (1)Institute of Psychobiology, Department

Effects of Acute Yohimbine Hydrochloride Supplementation on Repeated Supramaximal Sprint Performance.

12. Int J Environ Res Public Health. 2022 Jan 25;19(3):1316. doi: 10.3390/ijerph19031316. Effects of Acute Yohimbine Hydrochloride Supplementation on Repeated Supramaximal Sprint Performance. Barnes ME(1), Cowan CR(1), Boag LE(1), Hill JG(1), Jones ML(1), Nixon KM(1), Parker MG(1), Parker SK(1)

In vitro and in silico evaluation of the interaction of yohimbine with drug transporters and cytochrome P450 isoenzymes.

13. Eur J Pharmacol. 2025 Sep 15;1003:177869. doi: 10.1016/j.ejphar.2025.177869. Epub 2025 Jun 23. In vitro and in silico evaluation of the interaction of yohimbine with drug transporters and cytochrome P450 isoenzymes. Bajraktari-Sylejmani G(1), Kamaraj R(2), Pavek P(2), Burhenne J(1), Mikus G(

Synergistic interaction between clonidine and ACPA on the modulation of anxiety-like behaviors in non-acute restraint stress and acute restraint stress conditions.

14. Brain Res. 2025 Jan 15;1847:149304. doi: 10.1016/j.brainres.2024.149304. Epub 2024 Oct 29. Synergistic interaction between clonidine and ACPA on the modulation of anxiety-like behaviors in non-acute restraint stress and acute restraint stress conditions. Chitsaz A(1), Ebrahimi-Ghiri M(2), Z

Single-dose and steady-state pharmacokinetics of clomipramine, yohimbine and clomipramine/yohimbine combination: A clinical drug-drug interaction study.

15. Br J Clin Pharmacol. 2025 Mar;91(3):808-816. doi: 10.1111/bcp.16274. Epub 2024 Oct 21. Single-dose and steady-state pharmacokinetics of clomipramine, yohimbine and clomipramine/yohimbine combination: A clinical drug-drug interaction study. Leutzendorff A(1)(2), Al Jalali V(1), Bauer M(1)(3),

Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers.

36. Clin Pharmacokinet. 2024 Apr;63(4):469-481. doi: 10.1007/s40262-024-01350-x. Epub 2024 Feb 23. Time Course of the Interaction Between Oral Short-Term Ritonavir Therapy with Three Factor Xa Inhibitors and the Activity of CYP2D6, CYP2C19, and CYP3A4 in Healthy Volunteers. Rohr BS(1), Krohmer

Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans.

33. Eur J Clin Pharmacol. 2022 Jun;78(6):975-987. doi: 10.1007/s00228-022-03304-3. Epub 2022 Mar 3. Evaluation of CYP2C19 activity using microdosed oral omeprazole in humans. Elbe A(1), Foerster KI(1), Blank A(1), Rose P(1), Burhenne J(1), Haefeli WE(1), Mikus G(2). Author information: (1)Depar

Comparative study of dezocine, pentazocine and tapentadol on antinociception and physical dependence.

37. Life Sci. 2021 Nov 15;285:119996. doi: 10.1016/j.lfs.2021.119996. Epub 2021 Sep 28. Comparative study of dezocine, pentazocine and tapentadol on antinociception and physical dependence. Ahsan MZ(1), Zhao MJ(2), Shoaib RM(3), Zhang Y(4), Wang YX(5). Author information: (1)School of Pharmacy,

A Review on Pharmacokinetic and Pharmacodynamic Drug Interactions of Adrenergic β-blockers with Clinically Relevant Drugs-An Overview.

23. Curr Drug Metab. 2021;22(9):672-682. doi: 10.2174/1389200222666210614112529. A Review on Pharmacokinetic and Pharmacodynamic Drug Interactions of Adrenergic β-blockers with Clinically Relevant Drugs-An Overview. Maideen NMP(1), Rajkapoor B(2), Muthusamy S(2), Ramanathan S(2), Thangadurai SA(

Multiple cellular targets involved in the antidepressant-like effect of glutathione.

23. Chem Biol Interact. 2020 Sep 1;328:109195. doi: 10.1016/j.cbi.2020.109195. Epub 2020 Jul 22. Multiple cellular targets involved in the antidepressant-like effect of glutathione. Dafre AL(1), Rosa JM(1), Rodrigues ALS(1), Cunha MP(2). Author information: (1)Department of Biochemistry, Federa

Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial.

2. Trials. 2020 Jun 29;21(1):584. doi: 10.1186/s13063-020-04476-y. Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19): A structured summary of a study protocol for a randomised controlled trial. Stoll F(1), Blank A(2), Mi

STANDING SEDATION WITH XYLAZINE AND REVERSAL WITH YOHIMBINE IN JUVENILE ASIAN ELEPHANTS (ELEPHAS MAXIMUS).

40. J Zoo Wildl Med. 2021 Jun;52(2):437-444. doi: 10.1638/2020-0170. STANDING SEDATION WITH XYLAZINE AND REVERSAL WITH YOHIMBINE IN JUVENILE ASIAN ELEPHANTS (ELEPHAS MAXIMUS). Jansson T(1), Perera BV(2), Edner A(3), Fahlman Å(4). Author information: (1)Skeke Kvisthus 36, SE-755 96 Uppsala, Swede

Yohimbine in the treatment of orgasmic dysfunction.

6. Asian J Androl. 2007 May;9(3):403-7. doi: 10.1111/J.1745-7262.2007.00276.x. Yohimbine in the treatment of orgasmic dysfunction. Adeniyi AA(1), Brindley GS, Pryor JP, Ralph DJ. Author information: (1)Institute of Urology and Nephrology, London W1P 7EY, UK. AIM: To study the effect of yohimbine

A systematic review of pharmacological effects on human aversive memory.

5. Neurosci Biobehav Rev. 2026 Apr;183:106548. doi: 10.1016/j.neubiorev.2026.106548. Epub 2026 Jan 7. A systematic review of pharmacological effects on human aversive memory. Xia Y(1), Quednow BB(2), Bach DR(3). Author information: (1)Computational Psychiatry Research, Department of Adult Psychi

Pharmacological interventions in primary or secondary male anorgasmia: A systematic review.

25. Actas Urol Esp (Engl Ed). 2025 Nov;49(9):501835. doi: 10.1016/j.acuroe.2025.501835. Epub 2025 Sep 10. Pharmacological interventions in primary or secondary male anorgasmia: A systematic review. [Article in English, Spanish] Gómez-Bueno MP(1), Diaz-Hung AM(1), García-Perdomo HA(2). Author i

Do stress hormones influence choice? A systematic review of pharmacological interventions on the HPA axis and/or SAM system.

16. Soc Cogn Affect Neurosci. 2024 Oct 23;19(1):nsae069. doi: 10.1093/scan/nsae069. Do stress hormones influence choice? A systematic review of pharmacological interventions on the HPA axis and/or SAM system. Sarmiento LF(1), Ríos-Flórez JA(2), Rincón Uribe FA(3), Rodrigues Lima R(4), Kalenscher

Effects of dietary supplements on athletic performance in elite soccer players: a systematic review.

27. J Int Soc Sports Nutr. 2023 Dec;20(1):2236060. doi: 10.1080/15502783.2023.2236060. Effects of dietary supplements on athletic performance in elite soccer players: a systematic review. Abreu R(1)(2), Oliveira CB(1)(3), Costa JA(1), Brito J(1), Teixeira VH(2)(4)(5)(6). Author information: (1

Yohimbine as a pharmacological probe for alcohol research: a systematic review of rodent and human studies.

7. Neuropsychopharmacology. 2022 Nov;47(12):2111-2122. doi: 10.1038/s41386-022-01363-9. Epub 2022 Jun 27. Yohimbine as a pharmacological probe for alcohol research: a systematic review of rodent and human studies. Curley DE(1)(2), Vasaturo-Kolodner TR(1)(3), Cannella N(4), Ciccocioppo R(4), Haa

Augmentation of Psychotherapy with Neurobiological Methods: Current State and Future Directions.

31. Neuropsychobiology. 2021;80(6):437-453. doi: 10.1159/000514564. Epub 2021 Apr 28. Augmentation of Psychotherapy with Neurobiological Methods: Current State and Future Directions. Hertenstein E(1), Trinca E(1), Schneider CL(1), Wunderlin M(2), Fehér K(1), Riemann D(3), Nissen C(1). Author i

A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements.

48. Int J Impot Res. 2021 Apr;33(3):311-317. doi: 10.1038/s41443-020-0285-x. Epub 2020 May 1. A systematic review and evidence-based analysis of ingredients in popular male testosterone and erectile dysfunction supplements. Kuchakulla M(1), Narasimman M(1), Soni Y(1), Leong JY(2), Patel P(3), Ra