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The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis.

1. Reprod Biol Endocrinol. 2025 Jul 3;23(1):94. doi: 10.1186/s12958-025-01409-9. The effectiveness of nutritional supplements in improving polycystic ovary syndrome in women: a systematic review and network meta-analysis. Zhao G(#)(1)(2), Fan Y(#)(2), Li R(#)(2), Huang Y(2), Li W(2), Zhao Y(3), Z

Effects of dietary intervention on diabetic nephropathy: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials.

2. Front Endocrinol (Lausanne). 2024 Apr 29;15:1385872. doi: 10.3389/fendo.2024.1385872. eCollection 2024. Effects of dietary intervention on diabetic nephropathy: an umbrella review of systematic reviews and meta-analyses of randomized controlled trials. Cai L(1), Huang Y(2), Li X(1), Cao D(2)(

Effect of soy isoflavone supplementation on blood pressure: a meta-analysis of randomized controlled trials.

3. Nutr J. 2024 Mar 7;23(1):32. doi: 10.1186/s12937-024-00932-6. Effect of soy isoflavone supplementation on blood pressure: a meta-analysis of randomized controlled trials. Lei L(#)(1), Hui S(#)(2), Chen Y(1), Yan H(2), Yang J(3)(4), Tong S(5). Author information: (1)Department of Clinical Nutr

Effects of whey and soy protein supplementation on inflammatory cytokines in older adults: a systematic review and meta-analysis.

4. Br J Nutr. 2023 Mar 14;129(5):759-770. doi: 10.1017/S0007114522001787. Epub 2022 Jun 16. Effects of whey and soy protein supplementation on inflammatory cytokines in older adults: a systematic review and meta-analysis. Prokopidis K(1), Mazidi M(2), Sankaranarayanan R(3), Tajik B(4), McArdle A

Effect of soy isoflavones on C-reactive protein in chronic inflammatory disorders.

5. Int J Vitam Nutr Res. 2023 Oct;93(5):447-458. doi: 10.1024/0300-9831/a000751. Epub 2022 Mar 16. Effect of soy isoflavones on C-reactive protein in chronic inflammatory disorders. Gholami A(1)(2), Darudi F(1), Baradaran HR(3)(4), Hariri M(1). Author information: (1)Noncommunicable Diseases Re

A Meta-Analysis of Randomized Controlled Trials of the Effects of Soy Intake on Inflammatory Markers in Postmenopausal Women.

6. J Nutr. 2022 Jan 11;152(1):5-15. doi: 10.1093/jn/nxab325. A Meta-Analysis of Randomized Controlled Trials of the Effects of Soy Intake on Inflammatory Markers in Postmenopausal Women. Bajerska J(1), Łagowska K(1), Mori M(2), Reguła J(1), Skoczek-Rubińska A(1), Toda T(3), Mizuno N(3), Yamori Y

The effect of soy protein containing soy isoflavones on serum concentration of cell adhesion molecules: A systematic review and meta-analysis of randomized controlled trials.

7. Complement Ther Med. 2021 Sep;61:102764. doi: 10.1016/j.ctim.2021.102764. Epub 2021 Jul 29. The effect of soy protein containing soy isoflavones on serum concentration of cell adhesion molecules: A systematic review and meta-analysis of randomized controlled trials. Hariri M(1), Baradaran HR

Effects of soy isoflavone supplementation on patients with diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials.

8. Food Funct. 2021 Sep 7;12(17):7607-7618. doi: 10.1039/d1fo01175h. Epub 2021 Jul 8. Effects of soy isoflavone supplementation on patients with diabetic nephropathy: a systematic review and meta-analysis of randomized controlled trials. Wang X (1), Liang QF , Zeng X , Huang GX , Xin GZ , Xu YH

The effect of soy isoflavones on arterial stiffness: a systematic review and meta-analysis of randomized controlled trials.

9. Eur J Nutr. 2021 Mar;60(2):603-614. doi: 10.1007/s00394-020-02300-6. Epub 2020 Jun 11. The effect of soy isoflavones on arterial stiffness: a systematic review and meta-analysis of randomized controlled trials. Man B(1), Cui C(1), Zhang X(1), Sugiyama D(1)(2), Barinas-Mitchell E(1), Sekikawa

Equol Decreases Hot Flashes in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

10. J Med Food. 2019 Feb;22(2):127-139. doi: 10.1089/jmf.2018.4265. Epub 2018 Dec 28. Equol Decreases Hot Flashes in Postmenopausal Women: A Systematic Review and Meta-Analysis of Randomized Clinical Trials. Daily JW(1), Ko BS(2), Ryuk J(2), Liu M(3), Zhang W(3), Park S(3). Author information:

Effects of Soy Pretzel Consumption on Blood Biomarkers and Muscle Soreness After Intense Resistance Exercise in Healthy, Trained Males: A Preliminary Study.

11. J Strength Cond Res. 2026 Apr 1;40(4):422-430. doi: 10.1519/JSC.0000000000005348. Epub 2025 Dec 24. Effects of Soy Pretzel Consumption on Blood Biomarkers and Muscle Soreness After Intense Resistance Exercise in Healthy, Trained Males: A Preliminary Study. McClure J(1), Sommer A(1), Kraemer

Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial.

12. Eur J Nutr. 2025 Mar 25;64(3):138. doi: 10.1007/s00394-025-03588-y. Assessing the combined effects of Black Cohosh, Soy Isoflavones, and SDG Lignans on menopausal symptoms: a randomized, double-blind, placebo-controlled clinical trial. Pokushalov E(1)(2), Ponomarenko A(3), Garcia C(4), Kasim

The effect of soy isoflavones supplementation on metabolic status in patients with non-alcoholic fatty liver disease: a randomized placebo controlled clinical trial.

13. BMC Public Health. 2024 May 21;24(1):1362. doi: 10.1186/s12889-024-18812-3. The effect of soy isoflavones supplementation on metabolic status in patients with non-alcoholic fatty liver disease: a randomized placebo controlled clinical trial. Neshatbini Tehrani A(1)(2)(3), Hatami B(4), Daftar

The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy.

14. BMC Urol. 2024 May 3;24(1):102. doi: 10.1186/s12894-024-01483-y. The effect of a fermented soy beverage among patients with localized prostate cancer prior to radical prostatectomy. Lokeshwar SD(1), Ali A(2), Weiss TR(1), Reynolds J(3), Shuch BM(4), Ferencz T(5)(6), Kyriakides TC(3), Mehal W

The effect of soy isoflavones on non-alcoholic fatty liver disease and the level of fibroblast growth factor-21 and fetuin A.

15. Sci Rep. 2024 Mar 1;14(1):5134. doi: 10.1038/s41598-024-55747-6. The effect of soy isoflavones on non-alcoholic fatty liver disease and the level of fibroblast growth factor-21 and fetuin A. Neshatbini Tehrani A(1)(2)(3), Hatami B(4), Helli B(2)(3), Yari Z(5), Daftari G(6), Salehpour A(7), H

A Randomized Controlled Trial of Soy Isoflavone Intake on Mammographic Density among Malaysian Women.

15. Nutrients. 2023 Jan 6;15(2):299. doi: 10.3390/nu15020299. A Randomized Controlled Trial of Soy Isoflavone Intake on Mammographic Density among Malaysian Women. Rajaram N(1), Yap B(1), Eriksson M(2), Mariapun S(1), Tan LM(1), Sa'at H(3), Ho ELM(4), Taib NAM(3), Khor GL(5), Yip CH(1)(6), Ho WK

Soy isoflavones decrease fibroglandular breast tissue measured by magnetic resonance imaging in premenopausal women: A 2-year randomized double-blind placebo controlled clinical trial.

22. Clin Nutr ESPEN. 2022 Dec;52:158-168. doi: 10.1016/j.clnesp.2022.10.007. Epub 2022 Oct 26. Soy isoflavones decrease fibroglandular breast tissue measured by magnetic resonance imaging in premenopausal women: A 2-year randomized double-blind placebo controlled clinical trial. Lu LW(1), Chen

Genistein effect on cognition in prodromal Alzheimer's disease patients. The GENIAL clinical trial.

8. Alzheimers Res Ther. 2022 Nov 4;14(1):164. doi: 10.1186/s13195-022-01097-2. Genistein effect on cognition in prodromal Alzheimer's disease patients. The GENIAL clinical trial. Viña J(1), Escudero J(2), Baquero M(3), Cebrián M(1), Carbonell-Asíns JA(4), Muñoz JE(5), Satorres E(6), Meléndez JC(

Effect of soy isoflavones supplementation on migraine characteristics, mental status and calcitonin gene-related peptide (CGRP) levels in women with migraine: results of randomised controlled trial.

37. Nutr J. 2022 Jul 30;21(1):50. doi: 10.1186/s12937-022-00802-z. Effect of soy isoflavones supplementation on migraine characteristics, mental status and calcitonin gene-related peptide (CGRP) levels in women with migraine: results of randomised controlled trial. Babapour M(1), Khorvash F(2),

Effects of daidzein and genistein on markers of cardiovascular disease risk among women with impaired glucose regulation: a double-blind, randomized, placebo-controlled trial.

20. Food Funct. 2021 Sep 7;12(17):7997-8006. doi: 10.1039/d1fo00712b. Epub 2021 Jul 15. Effects of daidzein and genistein on markers of cardiovascular disease risk among women with impaired glucose regulation: a double-blind, randomized, placebo-controlled trial. Ye YB (1), He KY , Li WL , Zhuo

Lack of effects of S-equol-containing supplement on the pharmacokinetics of oral hormone therapy drugs for breast cancer.

1. Cancer Chemother Pharmacol. 2025 Dec 8;95(1):123. doi: 10.1007/s00280-025-04852-y. Lack of effects of S-equol-containing supplement on the pharmacokinetics of oral hormone therapy drugs for breast cancer. Sambe T(1)(2), Imamura CK(3), Hida N(4), Yamazaki T(4), Mizukami T(1), Ryu K(2), Fukuna

Diets containing pomegranate polyphenol and soy isoflavone attenuate contact hypersensitivity in mice.

4. Biosci Biotechnol Biochem. 2019 Mar;83(3):525-530. doi: 10.1080/09168451.2018.1543013. Epub 2018 Nov 10. Diets containing pomegranate polyphenol and soy isoflavone attenuate contact hypersensitivity in mice. Nagano T(1)(2), Ito H(3). Author information: (1)a Department of Food Science, Facul

Lack of combination effects of soy isoflavones and taxane chemotherapy of castration-resistant prostate cancer.

26. Prostate. 2019 Feb;79(2):223-233. doi: 10.1002/pros.23727. Epub 2018 Oct 21. Lack of combination effects of soy isoflavones and taxane chemotherapy of castration-resistant prostate cancer. Eskra JN(1), Schlicht MJ(1), Bosland MC(1). Author information: (1)Department of Pathology, College of

ME-143 Is Superior to Genistein in Suppression of WNT Signaling in Colon Cancer Cells.

33. Anticancer Res. 2017 Apr;37(4):1647-1653. doi: 10.21873/anticanres.11495. ME-143 Is Superior to Genistein in Suppression of WNT Signaling in Colon Cancer Cells. Pintova S(1), Planutis K(2), Planutiene M(2), Holcombe RF(2). Author information: (1)Department of Medicine, Division of Hematology

Combined Effects of Soy Isoflavones and β-Carotene on Osteoblast Differentiation.

21. Int J Environ Res Public Health. 2015 Oct 28;12(11):13750-61. doi: 10.3390/ijerph121113750. Combined Effects of Soy Isoflavones and β-Carotene on Osteoblast Differentiation. Nishide Y(1)(2), Tousen Y(3), Tadaishi M(4)(5), Inada M(6), Miyaura C(7), Kruger MC(8), Ishimi Y(9). Author informat

Combination of low dose of genistein and daidzein has synergistic preventive effects on isogenic human prostate cancer cells when compared with individual soy isoflavone.

32. Food Chem. 2013 Dec 1;141(3):1923-33. doi: 10.1016/j.foodchem.2013.04.109. Epub 2013 May 9. Combination of low dose of genistein and daidzein has synergistic preventive effects on isogenic human prostate cancer cells when compared with individual soy isoflavone. Dong X(1), Xu W, Sikes RA, W

Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth.

49. J Med Food. 2012 Dec;15(12):1081-90. doi: 10.1089/jmf.2011.0322. Epub 2012 Dec 10. Daidzein-estrogen interaction in the rat uterus and its effect on human breast cancer cell growth. Gaete L(1), Tchernitchin AN, Bustamante R, Villena J, Lemus I, Gidekel M, Cabrera G, Astorga P. Author infor

Vitamin D interactions with soy isoflavones on bone after menopause: a review.

17. Nutrients. 2012 Nov 6;4(11):1610-21. doi: 10.3390/nu4111610. Vitamin D interactions with soy isoflavones on bone after menopause: a review. Park CY(1), Weaver CM. Author information: (1)Department of Nutrition Science, Purdue University, 700 W State St, West Lafayette, IN 47907, USA. cypark@

Inhibition of ABCG2/BCRP transporter by soy isoflavones genistein and daidzein: effect on plasma and milk levels of danofloxacin in sheep.

35. Vet J. 2013 May;196(2):203-8. doi: 10.1016/j.tvjl.2012.09.012. Epub 2012 Oct 18. Inhibition of ABCG2/BCRP transporter by soy isoflavones genistein and daidzein: effect on plasma and milk levels of danofloxacin in sheep. Perez M(1), Otero JA, Barrera B, Prieto JG, Merino G, Alvarez AI. Author

Combined effect of soy isoflavones and vitamin D3 on bone loss in ovariectomized rats.

21. Nutrition. 2013 Jan;29(1):250-7. doi: 10.1016/j.nut.2012.03.009. Epub 2012 Aug 2. Combined effect of soy isoflavones and vitamin D3 on bone loss in ovariectomized rats. Chang KL(1), Hu YC, Hsieh BS, Cheng HL, Hsu HW, Huang LW, Su SJ. Author information: (1)Department of Biochemistry, Facult