내장육 복합체
Organ Meat Complex
📚 관련 논문 (43편)
1. Ecotoxicol Environ Saf. 2025 Apr 15;295:118120. doi: 10.1016/j.ecoenv.2025.118120. Epub 2025 Apr 5. Monitoring water contamination through shellfish: A systematic review of biomarkers, species selection, and host response. Fehrenbach GW(1), Murphy E(2), Tanoeiro JR(3), Pogue R(4), Major I(3).
1. Transbound Emerg Dis. 2022 May;69(3):958-973. doi: 10.1111/tbed.14118. Epub 2021 May 15. Role of abattoir monitoring in determining the prevalence of bovine tuberculosis: A systematic review and meta-analysis. Ramanujam H(1), Thiruvengadam K(2), Singaraj R(1), Palaniyandi K(1). Author information: (1)Department of Immunology, ICMR-National Institute for Research in Tuberculosis, Chennai, India. (2)Department of Statistics, ICMR-National Institute for Research in Tuberculosis, Chennai, India. Bovine tuberculosis (bTB) is one of the major zoonotic concerns of the world, as milk and meat from cattle are major products for human consumption. Bovine tuberculosis not only affects the health of cattle and poses an imminent zoonotic threat, but also causes significant economic loss in both developed and developing countries. This systematic review reports the prevalence of Mycobacterium tuberculosis complex (MTBC) organisms in slaughtered cattle showing tuberculosis-like lesion (TBL) with available literature worldwide. Appropriate keywords were used to search various databases to collect articles pertaining to slaughterhouse studies. Bovine TB prevalence, based on the prevalence of MTBC organisms in slaughtered cattle showing TBL by culture, microscopy, PCR and spoligotyping, was assessed in each study using a random-effects model and standardized mean with 95% confidence interval (CI). Heterogeneity was assessed by the I2 statistic. Publication bias was evaluated using funnel plots. Out of 72 hits, 37 studies were selected based on title and abstract. Ten articles were excluded due to lack of desired data, and 27 studies were included in the final analysis. From the selected articles, it was found that 426 [95% CI: 302-560] per 1,000 slaughtered cattle with TBL were positive for the presence of MTBC organisms. The sensitivity analysis showed that no individual study alone influenced the estimation of pooled prevalence. The prevalence of MTBC organisms in slaughtered cattle showing TBL by culture, microscopy, PCR and spoligotyping was 474[95% CI: 342-610], 385 [95% CI: 269-515], 218 [95% CI: 132-338], 326 [95% CI: 229-442], respectively, per 1,000 slaughtered cattle. Most of the slaughtered cattle were from the same locality as the slaughterhouse. The results obtained in this study suggest that abattoir monitoring can give an estimate of the prevalence of bTB in that locality. This study also emphasizes the need to test cattle and animal handlers who were in contact with bTB-positive cattle. © 2021 Wiley-VCH GmbH. DOI: 10.1111/tbed.14118 PMID: 33891372 [Indexed for MEDLINE]
2. Arch Anim Nutr. 2021 Aug;75(4):278-293. doi: 10.1080/1745039X.2021.1942765. Epub 2021 Jul 29. The effects of supplementation of Withania coagulans and α-tocopherol acetate in diets containing oxidised oil on growth performance, immune response and antioxidant indices in broiler chickens. Ali Tavakkoli A(1), Mirakzehi MT(1), Saleh H(1), Yousefi M(1). Author information: (1)Department of Animal Science, Higher Education Complex of Saravan, Saravan, Iran. This experiment was designed to study the effects of a hydroalcoholic fruit extract from Withania coagulans (WC) and α-tocopherol acetate (α-Toc) in diets containing oxidised oil on growth performance, immune response and antioxidant indices of broiler chickens. The experiment was arranged 2 × 3 × 2 factorial comprising the oxidised oil (0% and 2% diet), WC (0, 100 and 200 mg/kg diet) and α-Toc (0 and 200 mg/kg diet). A total of 600 1-day-old male broiler chickens of the Ross strain were randomly allocated to 12 treatments with 5 replicates of 10 birds each. On day 42, one bird from each replicate was sacrified to measure the lymphoid organ weights, intestinal morphometric characteristics, and malondialdehyde content in the thigh meat. Dietary inclusion of oxidised oil significantly reduced the body weight gain in birds receiving no dietary WC (p < 0.05). In contrast, dietary supplementation of WC at 100 mg/kg diet in birds fed with the diets lacking in WC and oxidised oil resulted in significant increase in body weight gain (p < 0.05). Dietary supplementation of WC significantly increased the total anti-sheep red blood cell titre (p < 0.01). The birds fed with the dietary oxidised oil revealed significantly higher values of malondialdehyde and lower glutathione peroxidase and superoxide dismutase activities (p < 0.05). Feeding diets containing WC resulted in a significant decrease in malondialdehyde content in thigh meat while conversely, increased the glutathione peroxidase and superoxide dismutase activities (p < 0.05). The findings indicated that the dietary inclusion of WC could be recommended as a potent alternative to synthetic compounds in order to improve broilers performance, immunity and meat quality under oxidative stress conditions. DOI: 10.1080/1745039X.2021.1942765 PMID: 34325577 [Indexed for MEDLINE]
1. Vet Anim Sci. 2026 Apr 21;32:100669. doi: 10.1016/j.vas.2026.100669. eCollection 2026 Jun. Effect of dietary supplementation with quercetin or rutin on the growth performance, meat quality and cecal microbiota of broilers under high stocking density. Zhao Y(1), Liu Y(1), Ning J(2), Li J(1), Dong Y(1). Author information: (1)Shanxi Key Laboratory of Animal Nutrition and Feed Development, College of Animal Science, Shanxi Agricultural University, Taigu 030801, China. (2)Shanxi Nongkang Xintuo Technology Development Co., Ltd., Yangqu 030100, China. This study aimed to investigate the effects of quercetin and rutin (the glycoside form of quercetin) on growth performance, organ indices, meat quality, serum biochemistry, intestinal morphology, and cecal microbiota of broilers under high stocking density, and compared their differential effects. A total of 480 one‑day‑old male Cobb500 broilers were randomly allocated to 6 treatment groups (6 replicates per group): a control group reared at 14 broilers/m², a high stocking density group at 20 broilers/m², and four high stocking density groups fed diets supplemented with 400 ppm or 800 ppm quercetin or rutin, respectively. The results of this study show that, compared with the control group, high stocking density, as well as supplementation with 400 ppm quercetin, 400 ppm rutin, and 800 ppm rutin, significantly reduced FI and BWG throughout the entire trial period. However, supplementation with 800 ppm quercetin showed a trend toward alleviating the reduction in FI and BWG caused by high stocking density. Supplementation with quercetin significantly increased the meat color of the pectorales at 45 min postmortem, whereas rutin supplementation significantly reduced drip loss of the pectorales at 24 h postmortem. Furthermore, quercetin and rutin supplementation significantly increased the chao1 index, enriched the beneficial intestinal bacteria Alistipes and Faecalibacterium, and reduced the relative abundance of the harmful bacterium Streptococcus at the genus level. In conclusion, quercetin and rutin differentially improved growth performance, meat quality, and cecal microbiota of broilers reared under high stocking density. © 2026 The Authors. DOI: 10.1016/j.vas.2026.100669 PMCID: PMC13127615 PMID: 42064682 Conflict of interest statement: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
2. Vet Med Int. 2026 Apr 15;2026:2822518. doi: 10.1155/vmi/2822518. eCollection 2026. Transcriptome Analysis Identifies Signaling Pathways Related to Performance, Meat Quality, and Organ Development in Multienzyme-Supplemented Kampung Unggul Balitbangtan (KUB) Chickens. Ayuti SR(1)(2), Lamid M(3), Warsito SH(3), Arif MAA(3), Kim EJ(4), Shin S(4), Hamid IS(5), Mafruchati M(6), Akmal M(7), Khairullah AR(8). Author information: (1)Doctoral Program of Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno Kampus C Mulyorejo, Surabaya, 60115, East Java, Indonesia, unair.ac.id. (2)Laboratory of Biochemistry, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Jl. Tgk. Hasan Krueng Kalee No. 4 Kopelma Darussalam, Banda Aceh, 23111, Aceh, Indonesia, unsyiah.ac.id. (3)Division of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno Kampus C Mulyorejo, Surabaya, 60115, East Java, Indonesia, unair.ac.id. (4)Department of Animal Science and Biotechnology, Kyungpook National University, Sangju, 37224, Republic of Korea, knu.ac.kr. (5)Division of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno Kampus C Mulyorejo, Surabaya, 60115, East Java, Indonesia, unair.ac.id. (6)Division of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Jl. Dr. Ir. H. Soekarno Kampus C Mulyorejo, Surabaya, 60115, East Java, Indonesia, unair.ac.id. (7)Laboratory of Histology, Faculty of Veterinary Medicine, Universitas Syiah Kuala, Jl. Tgk. Hasan Krueng Kalee No. 4 Kopelma Darussalam, Banda Aceh, 23111, Aceh, Indonesia, unsyiah.ac.id. (8)Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), Jl. Raya Bogor Km. 46 Cibinong, Bogor, 16911, West Java, Indonesia, brin.go.id. Kampung Unggul Balitbangtan (KUB) chicken is a superior Indonesian native breed with high adaptability, good growth potential, and desirable meat quality. Nutritional strategies such as multienzyme supplementation are increasingly applied to improve productivity and meat quality without altering basal diet composition. This study investigated the effects of dietary multienzyme supplementation, consisting of phytase and protease, on growth performance, carcass characteristics, organ development, meat quality, and muscle-related gene expression in KUB chickens. Sixteen one-day-old male KUB chicks were randomly allocated to four dietary treatments: a control diet without multienzymes and three diets supplemented with phytase (200 mg/kg) combined with protease at 300, 500, or 700 mg/kg of feed. Growth performance parameters were measured up to 45 days of age, followed by carcass evaluation, organ weight analysis, meat quality assessment, and transcriptomic and quantitative real-time PCR analyses of breast muscle tissue. Multienzyme supplementation significantly improved final body weight and feed conversion ratio, particularly during the finisher phase, while reducing feed intake at higher enzyme inclusion levels. Carcass percentage and breast weight were enhanced in multienzyme-treated groups, accompanied by favorable changes in digestive and immune organ development. Meat quality analysis showed increased water-holding capacity, reduced cooking loss, and improved color characteristics, notably higher redness and lower yellowness values. Transcriptomic profiling and gene expression analysis revealed significant modulation of key muscle growth-related genes, including ACTA1, MYBPC1, TGFβ2, IGF2, and MYH9, indicating adaptive transcriptional responses associated with improved nutrient utilization rather than direct structural muscle alterations. In conclusion, dietary supplementation with a combination of phytase and protease effectively enhances growth performance, feed efficiency, carcass traits, and meat quality in KUB chickens while modulating growth-related gene expression. Multienzyme inclusion represents a promising and cost-effective nutritional strategy for improving productivity and meat quality in native chicken production systems. Copyright © 2026 Siti Rani Ayuti et al. Veterinary Medicine International published by John Wiley & Sons Ltd. DOI: 10.1155/vmi/2822518 PMCID: PMC13083582 PMID: 42006446 Conflict of interest statement: The authors declare no conflicts of interest.
3. J Clin Virol. 2026 Apr 13;184:105944. doi: 10.1016/j.jcv.2026.105944. Online ahead of print. ONWARD: A one health, pan-European multidisciplinary network advancing surveillance, research, clinical management and control of zoonotic hepeviruses. Rivero-Juarez A(1), Velebit B(2), Johne R(3), Abravanel F(4), Reuter G(5), Dudman S(6), Kamar N(7), Jemersic L(8), di Bartolo I(9), Hasanoglu I(10), Anita A(11), Cook N(12), Ruta S(13), Nauwelaers I(14), Milojević L(2), Todorovska E(15), Mojsova S(16), Zerja A(17), Avellon A(18), der Honing RH(19), Harvala H(20), Nascimento MSJ(21), Mesquita JR(22); members of ONWARD. Author information: (1)Clinical Virology and Zoonoses Research Group, Unit of Infectious Diseases, Hospital Universitario Reina Sofía, Instituto Maimónides de Investigación Biomédica de Córdoba (IMIBIC), Universidad de Córdoba (UCO), Córdoba, Spain; Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: antonio.rivero@imibic.org. (2)Institute of Meat Hygiene and Technology, Belgrade 11040, Serbia. (3)Department of Biological Safety, German Federal Institute for Risk Assessment, Berlin, Germany. (4)Laboratoire de Virologie, Centre Hospitalier Universitaire de Toulouse, Toulouse 31300, France; Institut Toulousain des Maladies Infectieuses et Inflammatoires (Infinity), CNRS U5051, INSERM U1291, Université de Toulouse, Toulouse, France. (5)Department of Medical Microbiology, Medical School, University of Pécs, Szigeti út 12, Pécs H-7624, Hungary. (6)Institute of Clinical Medicine, University of Oslo, Oslo 0313, Norway; Department of Microbiology, Oslo University Hospital, Oslo 0372, Norway. (7)Department of Nephrology and Organ Transplantation, Toulouse University Hospital, INFINITY-Inserm U1291-CNRS U5051, University de Toulouse, Toulouse, France. (8)Department of Virology, Croatian Veterinary Institute, Zagreb 10000, Croatia. (9)Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanità, Rome, Italy. (10)Ankara Yildirim Beyazit University Faculty of Medicine, Ankara, Türkiye; Ankara Bilkent City Hospital, Infectious Diseases and Clinical Microbiology Department, Ankara, Türkiye. (11)Ion Ionescu de la Brad" Iasi University of Life Sciences, Regional Center of Advanced Research for Emerging Diseases, Zoonoses and Food Safety, Romania. (12)Jorvik Food Safety Services, York YO32 2GN, UK. (13)Carol Davila University of Medicine and Pharmacy, Bucharest, Romania; Stefan S. Nicolau Institute of Virology, Bucharest, Romania. (14)Sciensano, Brussels, Belgium. (15)Department of Functional Genetics, Abiotic and Biotic Stress, AgroBioInstitute, Agricultural Academy, Sofia, Bulgaria. (16)Faculty of Veterinary Medicine, University Ss Cyril and Methodius, Skopje, Macedonia. (17)Department of Infectious Diseases, Hospital University Center "Mother Teresa," Tirana, Albania. (18)Hepatitis Unit, National Center of Microbiology, Carlos III Institute of Health, Madrid, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. (19)Wageningen University and Research, Lelystad, the Netherlands. (20)University of Turku, Turku, Finland. (21)Faculty of Farmacy, University of Porto, Porto, Portugal. (22)School of Medicine and Biomedical Sciences (ICBAS), University of Porto, Porto, Portugal; LAQV, REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Porto, Portugal. Zoonotic hepeviruses, particularly hepatitis E virus (HEV, species Paslahepevirus balayani) represent a major yet underestimated public health challenge in Europe. Despite being the leading cause of acute viral hepatitis, surveillance, diagnostic practices and prevention strategies remain heterogeneous across EU/EEA countries, limiting comparability and hindering accurate burden estimates. Underdiagnosis is further compounded by extrahepatic manifestations and the growing impact of chronic HEV infection in immunocompromised patients. At the human-animal-environment interface, zoonotic HEV circulates widely in domestic pigs, wildlife and food products, while coordinated surveillance and control measures remain inconsistently implemented. The recent recognition of ratHEV (species Rocahepevirus ratti) as a cause of acute and chronic hepatitis in Europe further expands the spectrum of zoonotic hepevirus infections and underscores the need for integrated One Health approaches. To address these challenges, the One Health Zoonotic Hepevirus Network (ONWARD; COST Action CA24140) was launched in 2025 as a pan-European, multidisciplinary collaboration uniting experts across human, veterinary, food safety and environmental health sectors. ONWARD aims to harmonise diagnostic tools, strengthen clinical research, integrate multisectoral surveillance, promote capacity building and support evidence-based policy development. By fostering coordination with European stakeholders ONWARD provides a structured framework to strengthen preparedness, surveillance and response to zoonotic hepevirus threats across Europe. Copyright © 2026 The Authors. Published by Elsevier B.V. All rights reserved. DOI: 10.1016/j.jcv.2026.105944 PMID: 42001595 Conflict of interest statement: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Antonio Rivero-Juarez reports financial support was provided by European Cooperation in Science and Technology. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
4. J Vet Res. 2026 Feb 12;70(1):81-89. doi: 10.2478/jvetres-2026-0007. eCollection 2026 Mar. Cysticercus tenuicollis in selected locations in Poland: genetic diversity, prevalence and epidemiological patterns in roe deer (Capreolus capreolus) and moose (Alces alces). Pyziel AM(1), Banasiewicz J(2), Filip-Hutsch K(3), Slivinska K(4)(5), Kloch M(6), Świątek M(7), Zhytova O(8), Gmaj M(6), Klich D(6). Author information: (1)Department of Public Health Protection and Animal Welfare, Faculty of Biological and Veterinary Sciences, Institute of Veterinary Medicine, Nicolaus Copernicus University in Toruń, 87-100 Toruń, Poland. (2)Department of Biochemistry and Microbiology, Institute of Biology, Department of Food Hygiene and Public Health Protection, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warsaw, Poland. (3)Department of Food Hygiene and Public Health Protection, Institute of Veterinary Medicine, Warsaw University of Life Sciences, 02-776 Warsaw, Poland. (4)Museum and Institute of Zoology of the Polish Academy of Sciences, 00-818 Warsaw, Poland. (5)I.I. Schmalhausen Institute of Zoology of the National Academy of Sciences of Ukraine, 01030 Kyiv, Ukraine. (6)Department of Animal Genetics and Conservation, Department of Animal Breeding and Nutrition, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland. (7)Department of Animal Breeding and Nutrition, Institute of Animal Sciences, Warsaw University of Life Sciences, 02-787 Warsaw, Poland. (8)Polissia National University, 10008 Zhytomyr, Ukraine. INTRODUCTION: Taenia hydatigena is a widespread tapeworm. The predilection site of the adult form is the small intestine of its carnivore definitive hosts, and this site of the larval form, Cysticercus tenuicollis, is the abdominal visceral organs of its ungulate intermediate hosts. Cysticercal lesions are of food safety and economic importance, as they may condemn carcasses or internal organs of slaughtered animals and hunted game. The study aimed to evaluate the prevalence, intensity of infection and species composition of metacestodes from Polish roe deer and moose, and analyse the genetic diversity of the isolates. MATERIAL AND METHODS: Altogether, 167 roe deer (from the Mazowieckie and Łódzkie voivodeships) and 36 moose (from the Mazowieckie, Lubelskie and Podlaskie voivodeships) were studied. Metacestodes were collected post mortem and used for molecular investigations based on the partial cox1 (cytochrome c oxidase subunit 1) gene. RESULTS: The prevalence and the general intensity of infection were 9.6% and 1-6 cysts for roe deer, and 8.3% and 1-9 cysts for moose. Exclusively T. hydatigena infections were noted. Intraspecific genetic diversity of 1.42% was observed. The omentum and the mesentery were the most prevalent locations of metacestodes. CONCLUSION: Taenia hydatigena isolates from roe deer and moose varied genetically. Assuming national prevalence at the level observed in this study, the number of infected roe deer in Poland could exceed 18,000. Although T. hydatigena is not a zoonotic agent, its spread should be monitored and limited. Dogs should not be fed raw game meat in order to prevent parasitosis from spreading to farm animals. © 2026 Anna Maria Pyziel et al. DOI: 10.2478/jvetres-2026-0007 PMCID: PMC13054750 PMID: 41953739 Conflict of interest statement: Conflict of Interests Statement: The authors declare that there is no conflict of interests regarding the publication of this article.
5. Vet Med Sci. 2026 May;12(3):e70905. doi: 10.1002/vms3.70905. Advances in Avian Diagnostic Pathology: Current Trends, Challenges and Future Directions: A Review. Getnet GM(1)(2), Getnet MA(2), Atenaf AS(2). Author information: (1)Department of Veterinary Science, College of Agriculture and Natural Resource, Debre Markos University, Debre Markos, Ethiopia. (2)Departments of Veterinary Pathobiology, College of Veterinary Medicine and Animal Science, University of Gondar, Gondar, Ethiopia. Avian pathology is the scientific study of diseases in birds, focusing on the structural, functional and molecular changes in tissues and organs caused by infections, toxins, nutritional deficiencies or others. It plays a critical role in maintaining poultry health, ensuring food security and supporting economic growth. The aim of this review is to highlight current trends, challenges and future directions in avian pathology, with a special emphasis on advancements in diagnostic approaches that enhance avian disease detection and management. However, the practical application of advanced technologies in avian pathology remains limited, particularly in Ethiopia. Recent diagnostic advancements, including immunohistochemistry, molecular techniques as well as digital pathology, have improved the detection, characterisation and management of poultry diseases. Future directions emphasise the use of artificial intelligence (AI) and machine learning for accurate diagnostics, real-time disease monitoring and outbreak prediction. Ethiopia has achieved significant progress in avian pathology, particularly through polymerase chain reaction and histopathology. Despite ongoing advancements, the poultry industry continues to face challenges, including emerging and re-emerging pathogens, limited access to diagnostic infrastructure, zoonotic risks and antimicrobial resistance. Therefore, strengthening biosecurity practices, promoting responsible antimicrobial use and expanding the use of molecular, digital pathology and AI-supported diagnostic tools remain essential strategies for protecting both poultry population and public health. To further enhance disease detection and control, diagnostic capacity and professional training in avian pathology should be strengthened in Ethiopia. © 2026 The Author(s). Veterinary Medicine and Science published by John Wiley & Sons Ltd. DOI: 10.1002/vms3.70905 PMCID: PMC13051840 PMID: 41930907 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest.
6. Compr Rev Food Sci Food Saf. 2026 May;25(3):e70449. doi: 10.1111/1541-4337.70449. Gap Analysis of Metabolic Conversions of Off-Flavors and Antinutrients in Plant-Based Substrates. Kuijpers RI(1), de Moya Clark IO(2), Cavaco T(1), Nemanič V(3), Tagliabue B(4), Valero-Abad A(3), Wennekers WM(3), Zhang M(5), Van Zwet K(3), Abeln S(6), Moco S(5), Paul CE(4), Mouhib H(2), Notebaart RA(3), Smid EJ(3), Teusink B(1), Bachmann H(1)(7). Author information: (1)Systems Biology Lab, A-LIFE, AIMMS, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. (2)Department of Computer Science, VU Bioinformatics Group, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. (3)Food Microbiology, Wageningen University & Research, Wageningen, the Netherlands. (4)Biocatalysis Section, Department of Biotechnology, Delft University of Technology, Delft, the Netherlands. (5)Chemistry and Pharmaceutical Sciences, AIMMS, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands. (6)Department of Computer Science, AI Technology for Life, Universiteit Utrecht, Utrecht, the Netherlands. (7)NIZO Food Research, Ede, the Netherlands. To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant-based proteins is a promising route, but it also comes with challenges: Plant-based proteins often contain antinutritional factors and off-flavors, which can negatively impact consumer acceptance. Fermentation is broadly used to improve the quality of these products. However, how these unwanted molecules are synthesized and degraded is poorly understood, but this knowledge is essential for fermentation-based strategies to improve the sensory and nutritional value of plant-based products. This review provides a comprehensive overview of synthesis and degradation pathways of key antinutritional factors and off-flavor compounds in plant-based substrates, including aldehydes, furans, sulfur compounds, pyrazines, glycoalkaloids (GAs), pyrimidine glycosides, polyphenols, saponins, glucosinolates (GSLs), phytic acid (PA), oxalates, lectins, and protease and amylase inhibitors. With this we identified the research gaps in the field, which can be divided into three types: (i) degradation pathways that are unknown (furans, alkyl-methoxypyrazines, and dimethyl trisulfide), (ii) well-characterized pathways but typically not found in food-grade organisms (dimethyl sulfide, dimethyl disulfide, and isothiocyanates derived from GSLs), and (iii) pathways that are only described partially (GAs, saponins, polyphenols, PA, and pyrimidine glycosides). Other molecule classes, like aldehydes, alcohols, and oxalate, have well-characterized degradation pathways in food-grade organisms. Focusing future research on compounds with poorly understood degradation pathways will help to accelerate the development of more rationally designed cultures for producing healthy and sustainable plant-based foods. © 2026 The Author(s). Comprehensive Reviews in Food Science and Food Safety published by Wiley Periodicals LLC on behalf of Institute of Food Technologists. DOI: 10.1111/1541-4337.70449 PMCID: PMC13039779 PMID: 41918190 [Indexed for MEDLINE] Conflict of interest statement: H.B. is part time employed by NIZO Food Research. H.B. is part time employed by NIZO Food Research. The other authors declare no conflicts of interest.
7. J Food Sci. 2026 Apr;91(4):e71026. doi: 10.1111/1750-3841.71026. Lion's Mane Mushroom: Nutritional Profile, Bioactive Compounds, Functional Properties, and Applications in Functional Food Systems. Raja-Razali RB(1), Zahia-Azizan NA(1), Yee CS(1)(2), Ushidee-Radzi MA(1), Ilham Z(2)(3), Hamid N(4), Klaus A(5), Wan-Mohtar WAAQI(1). Author information: (1)Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia. (2)Biomass Energy Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia. (3)Centre for Science and Environment Studies, Institute of Islamic Understanding Malaysia, Kuala Lumpur, Malaysia. (4)Centre for Future Foods, Auckland University of Technology, Auckland, New Zealand. (5)Department of Industrial Microbiology, Institute of Food Technology and Biochemistry, Faculty of Agriculture, University of Belgrade, Belgrade, Serbia. Lion's Mane mushroom (Hericium erinaceus) holds a significant place in traditional Chinese medicine (TCM), valued for centuries for benefiting various internal organs and overall well-being. It is also celebrated as a culinary delicacy in East Asia, prized for its fleshy, meat-like texture and mild, seafood-like flavor. High concentrations of glutamic and aspartic acids generate a pronounced umami taste, enhancing its culinary appeal and supporting its use as a natural flavor enhancer. Nutritionally, it provides dietary fiber, essential minerals, and high protein content, notably in the mycelial biomass (up to 42.5% dry weight), making it especially suitable as a protein source in meat alternative applications. The mushroom's therapeutic potential is rooted in its novel bioactive constituents. Hericenones (in fruiting bodies) and erinacines (in mycelia) are diterpenoids that stimulate nerve growth factor (NGF) synthesis, supporting neuronal function. Furthermore, immunomodulatory β-glucans, antioxidant phenolic compounds, and ergothioneine contribute to its overall health benefits. However, these functional properties are predominantly supported by in vitro and animal studies. Despite growing interest in its medicinal properties, integrated evaluations of the nutritional composition, bioactive profile, and technological potential of H. erinaceus for modern food applications remain limited. By leveraging both its sensory attributes and scientifically validated functional value, H. erinaceus can be incorporated into beverages, staple foods, and meat substitutes. This comprehensive review examines its dual role as a medicinal and culinary mushroom, to hopefully enhance understanding of the mushroom and inspire its future applications in food technology. © 2026 Institute of Food Technologists. DOI: 10.1111/1750-3841.71026 PMID: 41906431 [Indexed for MEDLINE]
8. Animals (Basel). 2026 Mar 18;16(6):946. doi: 10.3390/ani16060946. Dose-Dependent Effects of Replacing Soybean Meal with Cottonseed Protein: Key to Optimizing Gut Health in Weaned Piglets. Jin H(1), Zhang A(2), Xu L(2), Tang D(1), Qin S(1). Author information: (1)College of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China. (2)Gansu Provincial Livestock Technology Promotion Station, Lanzhou 730000, China. This study aims to systematically assess the comprehensive, dose-dependent effects of substituting soybean meal with cottonseed protein at various ratios on weaned piglets. In total, 28-day-old weaned piglets (Duroc × Landrace × Large White crossbred; n = 45) were selected and then randomly categorized into three groups: 100% soybean meal (CON), 50% soybean meal +50% cottonseed protein (CSP50), and 100% CSP (CSP100) groups. After a 7-day adaptation period, the experiment continued for an additional 28 days. The results showed no significant differences among groups in growth performance, organ indices, most carcass traits, or meat quality indicators. The CSP50 group showed significantly reduced levels of diamine oxidase (DAO) and D-lactate and increased complexity of the colonic microbial network, with improved abundance of beneficial bacterial genera such as g_Blautia and g_Eubacterium. The CSP100 group showed elevated intestinal permeability, a decreased villus height, a villus-to-crypt ratio, specific digestive enzymes, a reduced Firmicutes/Bacteroidetes (F/B) ratio and abundant inflammation-associated bacteria, including g_Streptococcus. Furthermore, correlation analysis suggested that specific gut microorganisms and metabolic pathways may be potentially related to average daily gain (ADG), average daily feed intake (ADFI), the feed conversion ratio (F/G), DAO, and D-lactic acid. These findings suggest that dietary inclusion of 50% cottonseed protein (CSP50) is associated with sustained growth performance and enhanced gut health in weaned piglets, concurrent with shifts in the composition and predicted function of the gut microbiota. DOI: 10.3390/ani16060946 PMCID: PMC13023351 PMID: 41897923 Conflict of interest statement: The authors declare no conflicts of interest.
9. Food Res Int. 2026 May 31;232:118945. doi: 10.1016/j.foodres.2026.118945. Epub 2026 Mar 11. Microbiome crosstalk and nutrition: the interplay between gut microbiota-organ axis and dietary factors. Çelik MN(1), Dazıroğlu MEÇ(2), Pınar BA(3), Nanì MF(4), Romano B(5), Ağagündüz D(6), Capasso R(7). Author information: (1)Department of Nutrition and Dietetics, Faculty of Health Sciences, Ondokuz Mayis University, 55200 Samsun, Turkey. Electronic address: mensurenur.celik@omu.edu.tr. (2)Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University, 06490 Ankara, Turkey. (3)Department of Nutrition and Dietetics, Faculty of Health Sciences, Karamanoğlu Mehmetbey University, 70100 Karaman, Turkey. (4)Department of Pharmacy, University of Naples Federico II, Naples, 80131 Naples, Italy. Electronic address: mariafrancesca.nani@unina.it. (5)Department of Pharmacy, University of Naples Federico II, Naples, 80131 Naples, Italy. Electronic address: barbara.romano@unina.it. (6)Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University, 06490 Ankara, Turkey. Electronic address: duyguturkozu@gazi.edu.tr. (7)Department of Agricultural Sciences, University of Naples Federico II, Portici, 80055 Naples, Italy. Electronic address: rafcapas@unina.it. The gut microbiota (GM) is referred to as the central organ due to its dynamic and adaptable contact network with other organs through humoral, immunological, metabolic, endocrine, and neurological pathways. Recent studies have emphasized the concept of the "gut-organ axis", which shows that the effects of GM go beyond the gastrointestinal system (GIS) and encompass the reciprocal interactions between other organs. Communication along these axis occurs mainly through mediators such as short-chain fatty acids (SCFAs), microbial metabolites, neurotransmitters, cytokines, and hormonal signals. Therefore, imbalances in GM may surpass gut problems and be linked to diseases affecting the brain, liver, lungs, heart, mouth, skin, and many other organs. Understanding these reciprocal interactions can inform strategies for disease prevention and treatment. Emerging evidence suggests that interactions between the GM and other organ-specific metabolites it secretes are dynamic and influenced by various environmental and lifestyle factors, particularly diet. The gut and other organ microbiomes are maintained in balance with the help of nutritional supplements like probiotics, prebiotics, symbiotic, vitamins, omega-3 fatty acids, and dietary fiber. Consuming processed or red meat, high-fat, high-sugar, high-glycemic index foods, and excessive salt can upset this balance and raise the risk of systemic inflammation and disease. The purpose of this review is to examine the interactions between various organ-specific microbiomes in the human body, to elucidate the effects of these interactions on health, and to highlight how microbiome-targeted nutritional interventions can modulate these interactions, potentially affecting disease risk and overall metabolic homeostasis. Copyright © 2026 The Authors. Published by Elsevier Ltd.. All rights reserved. DOI: 10.1016/j.foodres.2026.118945 PMID: 41895994 [Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
10. Mar Drugs. 2026 Mar 20;24(3):116. doi: 10.3390/md24030116. Marine Bioactive Compounds from Functional Seafoods: Pharmacological Mechanisms and Health Applications. Davran Bulut S(1)(2), Yaktubay Döndaş N(1)(3)(4), Koçhan S(1), Arslan BN(3)(5), Tamer MA(1), Osmani M(6), Baraketi S(7), Khwaldia K(7), Zhang Z(8), Döndaş HA(1)(5)(9), Esatbeyoglu T(10), Katikou P(11), Ozogul F(12). Author information: (1)Department of Biotechnology, Institute of Natural and Applied Sciences, Çukurova University, Balcalı, 01330 Adana, Türkiye. (2)Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Türkiye. (3)Department of Medical Pharmacology, Faculty of Medicine, Çukurova University, Balcalı, 01330 Adana, Türkiye. (4)Department of Translational Medicine, Institute of Health Sciences, Çukurova University, Balcalı, 01330 Adana, Türkiye. (5)Department of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Çukurova University, Balcalı, 01330 Adana, Türkiye. (6)Faculty of Food Technology, University of Mitrovica "Isa Boletini", Str. Ukshin Kovacica, 40000 Mitrovica, Kosovo. (7)Laboratory of Natural Substances (LSN), National Institute of Research and Physicochemical Analysis (INRAP), BiotechPole Sidi Thabet, Sidi Thabet 2020, Tunisia. (8)State Key Laboratory of Marine Food Processing & Safety Control, College of Food Science and Engineering, Ocean University of China, Qingdao 266404, China. (9)Department of Advanced Materials and Nanotechnology, Institute of Natural and Applied Sciences, Çukurova University, Balcalı, 01330 Adana, Türkiye. (10)Department of Molecular Food Chemistry and Food Development, Institute of Food and One Health, Gottfried Wilhelm Leibniz University Hannover, Am Kleinen Felde 30, 30167 Hannover, Germany. (11)Veterinary Research Institute of Thessaloniki, Hellenic Agricultural Organization-DIMITRA, Ktima Thermis, 57001 Thessaloniki, Greece. (12)Department of Seafood Processing Technology, Faculty of Fisheries, Çukurova University, Balcalı, 01330 Adana, Türkiye. Functional seafoods derived from marine organisms, including fish, shellfish and algae, are gaining increasing attention due to their high content of bioactive compounds, such as omega-3 fatty acids, peptides, polysaccharides and antioxidants, which provide health benefits beyond basic nutrition. These marine-derived compounds exhibit a wide range of biological activities and have been investigated for their potential roles in the prevention and management of chronic diseases, including cardiovascular, neurodegenerative, cancer and gastrointestinal disorders. Their effects are largely mediated through anti-inflammatory, antioxidant and immunomodulatory mechanisms. Advances in biotechnology, including genetic engineering and improved extraction of bioactive compounds, have enhanced the nutritional quality and pharmacological relevance of functional seafoods. At the same time, sustainable aquaculture practices are being developed to reduce environmental impacts. Nevertheless, challenges such as regulatory inconsistencies, scalability issues and limited understanding of bioavailability and long-term effects still persist. These constraints should be considered when interpreting mechanistic and efficacy findings presented across different study designs and exposure conditions. Future perspectives highlight innovations in precision aquaculture, waste valorisation and traceability as key strategies to improve sustainability and strengthen consumer trust. This review summarizes current knowledge on functional seafoods, with emphasis on pharmacological mechanisms, clinical applications and the need for interdisciplinary research to optimize their health benefits and commercial potential. DOI: 10.3390/md24030116 PMCID: PMC13027525 PMID: 41892975 [Indexed for MEDLINE] Conflict of interest statement: Author Khaoula Khwaldia was employed by the company BiotechPole Sidi Thabet. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
11. Sci Rep. 2026 Mar 19;16(1):9536. doi: 10.1038/s41598-026-43600-x. Fish meal replacement with poultry byproduct and black soldier fly larvae proteins: effects on growth, flesh quality, bioactivity, and physiological responses of Nile tilapia. Aref SM(1), Alian HA(2), Khodary FM(3), Székács A(4), Saeed O(5), Eid MH(6)(7), Elwakeel AE(8), Alhumedi M(9), Ahmed AF(9), Moussa-Ayoub TE(1), Salem ME(10). Author information: (1)Food Technology Department, Faculty of Agriculture, Suez Canal University, Ismailia, 41522, Egypt. (2)Nutrition and Clinical Nutrition Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt. heba.alian@vet.suez.edu.eg. (3)Cytology and Histology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt. (4)Agro-Environmental Research Centre, Doctoral School of Environmental Science, Institute of Environmental Sciences, Hungarian University of Agriculture and Life Sciences (MATE), Páter Károly u. 1, Gödöllő, 2100, Hungary. (5)Agro-Environmental Research Centre, Doctoral School of Environmental Science, Institute of Environmental Sciences, Hungarian University of Agriculture and Life Sciences (MATE), Páter Károly u. 1, Gödöllő, 2100, Hungary. omar.almashreqi@gmail.com. (6)Institute of Environmental Management, Faculty of Earth Science, University of Miskolc, Egyetemváros, Miskolc, 3515, Hungary. (7)Geology Department, Faculty of Science, Beni-Suef University, Beni-Suef, 65211, Egypt. (8)Agricultural Engineering Department, Faculty of Agriculture and Natural Resources, Aswan University, Aswan, 81528, Egypt. (9)Department of Biology, College of Science, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia. (10)Food Technology Department, Faculty of Agriculture, Suez Canal University, Ismailia, 41522, Egypt. m.salm68@yahoo.com. The demand for fishmeal is increasing, but its supply is stagnating or even declining. There is an urgent need to find an eco-friendly and cost-effective alternative protein source. This study evaluated poultry by-product and insect meal as alternatives to fishmeal for the health performance and bioactivity of Nile tilapia. A Nile tilapia fry was divided into four groups with three replicates (No = 168). The first group was fed a basal diet containing 20% fishmeal (TFM). The second, third, and fourth groups received a basal diet where the fishmeal was substituted with poultry by-product meal (TPM), insect meal from Hermetia illucens (TIM), and a mixture of poultry by-product and insect meal (TMIX), respectively. The overall growth performance data indicated that TFM and TIM significantly achieved the highest growth rates and feed utilization (P < 0.05). The TIM diet significantly exhibited the highest total phenolic content, and both TIM and TFM showed superior antioxidant activity in fish muscle. There were no abnormal hematological or serum biochemical parameters observed in Nile tilapia fed insect meal and/or poultry by-product. The fish fillet samples from all groups were microbiologically safe for human consumption. Fish fed TIM displayed the lowest levels of TNF-α and the highest levels of IL-10 (P < 0.05). All the groups exhibited normal architecture of the internal organs. The significantly highest recorded absorption surface area was found in both TFM and TIM diets (P < 0.05). The NF-κB immunostaining showed no significant changes among experimental groups (P > 0.05). Based on this study, it can be suggested that the insect meal can be a sustainable and cost-effective substitute for conventional fishmeal in aquaculture feed formulations. © 2026. The Author(s). DOI: 10.1038/s41598-026-43600-x PMCID: PMC13004979 PMID: 41857126 [Indexed for MEDLINE] Conflict of interest statement: Declarations. Competing interests: The authors declare no competing interests.
12. Int J Mol Sci. 2026 Mar 4;27(5):2389. doi: 10.3390/ijms27052389. Cellular Senescence Triggered by Food and Environmental Genotoxins. Kaina B(1), Tomicic MT(1), Christmann M(1). Author information: (1)Institute of Toxicology, University Medical Center of the Johannes Gutenberg University Mainz, Obere Zahlbacher Str. 67, D-55131 Mainz, Germany. Cellular senescence (CSEN) is caused by a variety of factors that trigger complex molecular pathways. These include telomere shortening, oncogene activation and replicative stress, as well as DNA damage caused by genotoxic anticancer drugs and endogenous and exogenous genotoxins. Here, we review the induction of CSEN by exogenous genotoxic insults resulting from food and environmental exposures. The available data show that genotoxins/carcinogens in tobacco smoke and smokeless tobacco, in the environment, in food, beverages and life-style products induce CNS. The exposures include N-nitroso compounds, polycyclic aromatic hydrocarbons, heterocyclic aromatic amines, acrylamide, heavy metals, fine dust, mycotoxins, phytotoxins, and phycotoxins. Also, heme in red meat contributes to CSEN as it catalyzes the formation of genotoxic species in the colon. Induction of CSEN by external genotoxins/carcinogens is bound on the DNA damage response pathway (DDR), which relies on activation of the ATM/ATR-CHK2/CHK1-p53-p21 axis and the p53-independent p16/p14 axis, eliciting cyclin-dependent kinase inhibition and permanent cell cycle arrest. Other factors that can be involved are DREAM, MAPK, cGAS/Sting, and NF-κB. The accumulation of non-repaired DNA damage triggering CSEN following external genotoxic exposures may contribute significantly to the amelioration of senescent cells and organ failure with age in humans. Senescent cells drive, via the senescence-associated secretory phenotype (SASP), inflammation that is involved in many diseases, including cancer. Although most of the studies were performed with in vitro cell systems, the consequences of CSEN induction by genotoxic nutritional components and environmental exposures seem to be underestimated. Since CSEN correlates with aging, it is reasonable to conclude that exogenous genotoxic pollutants contribute significantly to the aging process through CSEN induction. In light of these findings, it is deduced that reducing genotoxin exposures and using "rejuvenation" supplements (senotherapeutics) are reasonable strategies to counteract cellular senescence and the aging process. DOI: 10.3390/ijms27052389 PMCID: PMC12986306 PMID: 41828605 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest.
13. J Anim Sci Biotechnol. 2026 Mar 13;17(1):48. doi: 10.1186/s40104-026-01376-0. New insights into the skeletal muscle circadian clock in ruminants. Wang Q(#)(1), Chen Y(#)(1), Chen Y(1), Ling Y(1), Gao S(2), Zhang Z(3), Ren D(4). Author information: (1)College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. (2)College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China. (3)College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. zhangzijun@ahau.edu.cn. (4)College of Animal Science and Technology, Anhui Agricultural University, Hefei, 230036, China. rendl@ahau.edu.cn. (#)Contributed equally Circadian rhythms are endogenous oscillations with a period of approximately 24 h. They enable organisms to anticipate and adapt to daily environmental changes, such as light and temperature. As the largest metabolic and motor organ in the body, skeletal muscle plays a decisive role in determining meat production efficiency in ruminants. Skeletal muscle development is largely governed by the proliferation and myogenic differentiation capacity of skeletal muscle satellite cells (SMSCs). More than 2,300 genes in skeletal muscle exhibit circadian oscillatory expression and are extensively involved in myogenesis, transcriptional regulation, and metabolic processes. The rhythmic expression of these genes is modulated by external factors including the photoperiod, feeding behavior, gut microbiota, and physical activity. Disruption of the endogenous circadian timing system can inhibit SMSC proliferation and myogenic differentiation, thereby impairing normal muscle development. Therefore, this review focuses on key management aspects of ruminant production-such as environmental control, nutritional regulation, and exercise management-and systematically elaborates on how these husbandry strategies may influence SMSC fate by modulating the circadian clock, along with the underlying molecular mechanisms. © 2026. The Author(s). DOI: 10.1186/s40104-026-01376-0 PMCID: PMC12983946 PMID: 41821117 Conflict of interest statement: Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: All the authors have approved the final manuscript. Competing interests: The authors declare no competing interests.
14. Trop Anim Health Prod. 2026 Mar 12;58(2):166. doi: 10.1007/s11250-026-04979-x. Harnessing the dietary potential of cassava leaf and peel meals as novel feed resources in broiler nutrition. Mbajiorgu CA(1), Ogbuewu IP(2)(3). Author information: (1)Department of Agriculture and Animal Health, University of South Africa, Florida Science Campus, Private Bag X6, Florida, 1710, South Africa. (2)Department of Agriculture and Animal Health, University of South Africa, Florida Science Campus, Private Bag X6, Florida, 1710, South Africa. dr.ogbuewu@gmail.com. (3)Department of Animal Science and Technology, Federal University of Technology, P.M.B. 1526, Owerri, Imo State, Nigeria. dr.ogbuewu@gmail.com. Energy and protein are important in chicken diets, with maize and soybeans traditionally serving as primary sources. Rising costs of maize and soybean meal have necessitated the search for sustainable alternatives, such as abundant cassava peel meal (CPM) and cassava leaf meal (CLM). CPM is rich in carbohydrates, minerals, and fibre, while CLM has high levels of amino acids, vitamins, and carotenoids. Both are deficient in sulphur-amino acids (cysteine and methionine) but rich in lysine, an amino acid often lacking in cereal grains. Low inclusion levels (≤ 12.5% CPM or ≤ 5% CLM) improve broiler growth performance compared to conventional diets without negative effects on carcass yield, meat quality, organ weights, or blood parameters, while lowering feed costs and increasing gross margins. In contrast, higher inclusion levels (> 20% CPM or > 15% CLM) impair growth and blood indices, due to high fibre content, residual hydrogen cyanide (HCN), and other antinutritional factors (ANFs) like condensed tannins and phytates. Enzyme supplementation alleviates these adverse impacts and enhances nutrient utilisation, though outcomes vary with processing method, plant part used, diet composition, and inclusion rate. The practical implication of these findings is that diets containing cassava by-products require careful formulation, especially to balance the limiting sulphur-containing amino acids. Future research should optimise processing techniques and enzyme combinations to support higher inclusion levels and maximising the potential of these abundant resources. DOI: 10.1007/s11250-026-04979-x PMCID: PMC12982263 PMID: 41817879 Conflict of interest statement: Declarations. Ethical approval: Not applicable. Consent to participate: Not applicable. Consent for publication: Not applicable. Conflict of interest: Authors have no conflict interest to state.
15. Medicine (Baltimore). 2026 Mar 6;105(10):e47741. doi: 10.1097/MD.0000000000047741. The causality between dietary intake and allergic diseases: A two-sample Mendelian randomization analysis. Liu W(1)(2), Mao C(1)(2), Ji H(1)(2), Cheng F(1), Li T(1)(2), Li Q(1)(2), Zhao C(1)(2), An Y(1)(2). Author information: (1)Department of Otolaryngology-Head and Neck Surgery, the Second Hospital, Taiyuan, Shanxi, China. (2)Shanxi Medical University, Taiyuan, Shanxi, China. Allergic diseases are common chronic inflammatory conditions, which can affect multiple organs in severe cases, resulting in complex and varied clinical manifestations. Therefore, their management requires a more comprehensive and long-term strategy. A well-balanced diet is crucial in this context, as it regulates the immune system and improves atopic constitution, making it a key measure in preventing and controlling allergic diseases. Unlike observational studies prone to confounding and reverse causality, Mendelian randomization uses genetic variants as instrumental variables for stronger causal inference. This study employed the two-sample Mendelian randomization to investigate the potential causal relationships between 22 dietary factors and allergic diseases. The primary methods used were the weighted median method, MR-Egger regression, and inverse-variance weighted. To ensure the robustness and accuracy of the results, a series of sensitivity analyses, heterogeneity tests, and pleiotropy assessments were conducted. The study identified 7 dietary factors associated with allergic asthma, atopic dermatitis, and allergic rhinitis. The oily fish (OR: 0.666; 95% CI: 0.468-0.949; P = .024), dried fruit (OR: 0.463; 95% CI: 0.307-0.697; P = .00023), and cereal intake (OR: 0.595; 95% CI: 0.355-0.998; P = .049) was found to have a protective effect against asthma. The fresh fruit (OR: 0.592; 95% CI: 0.384-0.913; P = .018), tea (OR: 0.774; 95% CI: 0.603-0.995; P = .046), cereal (OR: 0.635; 95% CI: 0.430-0.939; P = .023), and processed meat intake (OR: 0.481; 95% CI: 0.294-0.787; P = .0036) were protective factors against atopic dermatitis. No significant causal relationships were observed between other dietary factors and these 3 diseases. These findings underscore the critical role of a balanced diet in the prevention and management of allergic diseases and highlight the potential of nutritional interventions in the future control and treatment of these conditions. Copyright © 2026 the Author(s). Published by Wolters Kluwer Health, Inc. DOI: 10.1097/MD.0000000000047741 PMCID: PMC12975205 PMID: 41790686 [Indexed for MEDLINE] Conflict of interest statement: The authors have no conflicts of interest to disclose.
16. Vet Sci. 2026 Feb 13;13(2):188. doi: 10.3390/vetsci13020188. Effects of Dietary Black Cumin Seed (Nigella sativa L.) Meal on Performance, Gut Health, and Meat Quality of Japanese Quail. Çakır K(1), Çayan H(2). Author information: (1)Graduate School of Natural and Applied Sciences, Kırşehir Ahi Evran University, 40100 Kırşehir, Türkiye. (2)Department of Animal Science, Faculty of Agriculture, Kırşehir Ahi Evran University, 40100 Kırşehir, Türkiye. This study investigated the effects of dietary black cumin seed meal (BCSM) supplementation on growth performance, carcass traits, intestinal histomorphology, cecal microbiota, meat quality, and breast meat malondialdehyde (MDA) levels in Japanese quail. A total of 200 one-week-old quail were randomly allocated to four dietary treatments containing 0, 5, 10, or 20 g/kg BCSM for a 35-day experimental period, with five replicates per treatment. Dietary BCSM supplementation did not significantly affect body weight, body weight gain, feed intake, or conversion ratio (p > 0.05). However, carcass weight was significantly increased in birds fed 20 g/kg BCSM (p < 0.05), while carcass yield and relative internal organ weight remained unchanged. Intestinal histomorphology was markedly influenced by dietary treatments (p < 0.05), with improved villus height and villus height-to-crypt depth ratio in the jejunum and ileum of BCSM-fed birds. In addition, cecal microbiota analysis revealed a dose-dependent increase in Lactobacillus spp. (p < 0.05), whereas Escherichia coli counts were numerically reduced but not statistically affected (p > 0.05). Meat quality evaluation showed that BCSM supplementation significantly increased breast meat lightness (L*) and water-holding capacity and reduced post-slaughter pH values (p < 0.05). Lipid oxidation, as assessed by malondialdehyde (MDA) concentrations, was observed to be significantly lower in breast meat during refrigerated storage, suggesting a potential improvement in oxidative stability and a possible contribution to extended shelf life (p < 0.05). In conclusion, dietary inclusion of black cumin seed meal, particularly at 20 g/kg, positively modulated intestinal health, cecal microbiota composition, and meat oxidative stability without compromising growth performance. Owing to its high nutritional value and rich bioactive compound profile, BCSM can be considered a functional and sustainable feed ingredient for quail nutrition. DOI: 10.3390/vetsci13020188 PMCID: PMC12945143 PMID: 41745982 Conflict of interest statement: The authors declare no conflicts of interest.
17. Poult Sci. 2026 May;105(5):106608. doi: 10.1016/j.psj.2026.106608. Epub 2026 Feb 10. Synergistic impacts of garlic and curcumin on growth performance, carcass characteristics, immunity, antioxidant status, and gut histology of broiler chickens. Saber HS(1), Khalil HA(1), El-Kashef MMA(2), Elsayed DAA(3), Anas H(4), Alharbi HM(5), Alwutayd KM(5), Khan MMH(6), Abd El-Hack ME(7), Youssef IM(8). Author information: (1)Animal Production Department, Faculty of Agriculture, Suez Canal University, Ismailia 41522, Egypt. (2)Animal and Poultry Production Department, Faculty of Environmental Agricultural Sciences, Arish University, Arish, Egypt. (3)Department of Poultry Breeding, Animal Production Research Institute, Agricultural Research Center, Dokki, Giza 12618, Egypt. (4)Animal Production Department, Faculty of Agriculture, Al-Azhar University, Assiut branch 71524, Egypt. (5)Department of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia. (6)Department of Biochemistry and Chemistry, Faculty of Biotechnology and Genetic Engineering, Sylhet Agricultural University, 3100 Sylhet, Bangladesh. Electronic address: mehedi2001dbdb@gmail.com. (7)Department of Industrial Pharmacy, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology (MUST), P.O. Box 77, Giza, Egypt. (8)Animal Production Systems Research Department, Animal Production Research Institute, Agricultural Research Center, Dokki, Giza 12618, Egypt. This investigation estimated the synergistic influences of garlic (Ga) and curcumin (Cu) supplementation on the growth performance, carcass features, immunity, antioxidant capacity, and gut histology of broiler chickens. A total of 300 Cobb 500 chicks were assigned to five dietary treatments: T1 (control) fed only basal diet; T2 fed basal diet supplemented with 0.25% Ga+0.25% Cu, T3: fed basal diet supplemented with 0.25% Ga+0.50% Cu, T4: fed basal diet supplemented with 0.50% Ga+0.25% Cu, and T5: fed basal diet supplemented with 0.50% Ga+0.50% Cu. The maximum inclusion level (0.50% Ga + 0.50% Cu, equivalent to 5 g/kg diet each) produced the greatest final body weight, weight gain and feed conversion ratio despite no change in feed intake according to the results which demonstrated a significant enhancement in growth performance with supplementation. While intramuscular fat dropped in the supplemented groups carcass yield and breast protein content increased significantly suggesting improved nutrient utilization and lean tissue accretion. Furthermore, birds given garlic and curcumin had improved mineral content in their breast meat and higher serum calcium and phosphorus concentrations. As evidenced by increased albumin levels and decreased serum AST and creatinine supplementation improved liver and kidney function indicators. IgG and IgM concentrations were highest in T5 birds, indicating an improvement in immune status. Superoxide dismutase activity was higher and malondialdehyde levels were lower, indicating a reduction in oxidative stress and an improvement in antioxidant defenses. Histologically supplemented birds-especially those in T5-showed longer healthier intestinal villi and well-preserved bursal follicles suggesting enhanced immune organ development and gut integrity. T5 achieved the greatest net revenue and efficiency according to economic evaluation. The results showed that curcumin and garlic work in concert to improve broiler performance, health and profitability. This is a natural substitute for antibiotics. Copyright © 2026. Published by Elsevier Inc. DOI: 10.1016/j.psj.2026.106608 PMCID: PMC12945627 PMID: 41723958 [Indexed for MEDLINE] Conflict of interest statement: Disclosures The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
18. Poult Sci. 2026 May;105(5):106648. doi: 10.1016/j.psj.2026.106648. Epub 2026 Feb 16. Effects of dietary supplementation with encapsulated capsaicinoids on growth performance and cecal microbiota in broiler chickens. Hou K(1), Li J(2), Wang Y(3), He M(4), Wang H(5). Author information: (1)College of Animal Science, Zhejiang University, The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, Hangzhou 310058, China. (2)College of Animal Science and Technology, Zhejiang Agriculture & Forestry University, Hangzhou, Zhejiang 311300, China. (3)College of Animal Science and Technology, Zhejiang Agriculture & Forestry University, Hangzhou, Zhejiang 311300, China. Electronic address: rationalwang@163.com. (4)Innovation Division, Lucta (Guangzhou) Flavours Co. Ltd, Guangzhou 510530, China. (5)College of Animal Science, Zhejiang University, The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, Hangzhou 310058, China. Electronic address: haifengwang@zju.edu.cn. Capsaicinoids (CAPs) are widely investigated as natural alternatives to antibiotic growth promoters; however, most studies have examined capsaicin (CAP) alone, and the combined effects of CAP and dihydrocapsaicin (DHC) in encapsulated form remain largely unexplored in broilers. This study evaluated dietary encapsulated capsaicinoids (E-CAPs; 0.47% CAP and 0.22% DHC w/w) on growth performance, meat quality, serum biochemistry, antioxidant status, organ indices, intestinal morphology, and gut microbiota in Arbor Acres broilers. A total of 384 broilers were randomly assigned to a basal diet (CON) or diets supplemented with 150 mg/kg (LDC) or 450 mg/kg (HDC) E-CAPs. Compared with CON, HDC increased average daily gain and reduced the feed-to-gain ratio during the grower and overall periods (P < 0.05), whereas LDC showed limited effects. HDC also decreased serum alanine aminotransferase and total bile acid levels relative to CON (P < 0.05), without differences in other biochemical or antioxidant parameters or in organ indices and intestinal morphology, indicating good metabolic safety. Both LDC and HDC reduced crude fat content and thiobarbituric acid reactive substances levels in breast meat during refrigerated storage, without affecting meat color, compared with the CON group (P < 0.05). Relative to CON, HDC reduced the relative abundance of Actinomycetota and increased the relative abundances of Clostridium_innocuum, Alistipes, and Turicimonas (q < 0.05), accompanied by predicted enrichment of pathways related to bacterial secretion systems and antimicrobial resistance. Overall, supplementation with 450 mg E-CAPs/kg diet (≈3.1 mg total CAPs/kg) enhanced growth performance, improved meat quality, and beneficially modulated gut microbiota while maintaining metabolic and intestinal health, supporting the combined encapsulated CAP - DHC formulation as a safe and effective feed additive for broilers. Copyright © 2026. Published by Elsevier Inc. DOI: 10.1016/j.psj.2026.106648 PMCID: PMC12934302 PMID: 41722229 [Indexed for MEDLINE] Conflict of interest statement: Disclosures The authors declare that there are no conflicts of interest, financial or personal relationships with other people or organizations that could inappropriately influence or bias the content of this paper. All authors have reviewed and approved the final version of the manuscript.
19. Anim Nutr. 2026 Jan 3;24:291-302. doi: 10.1016/j.aninu.2025.11.004. eCollection 2026 Mar. Differential impacts of dietary distillers' dried grains with solubles levels on Cherry Valley ducks: Insights into meat quality and intestinal health. Liu Y(1), Deng J(1), Xie Y(1), Chang J(1), Zhao H(1), Chen X(1), Liu G(1), Tang J(1), Tian G(1), Cai J(1), Jia G(1). Author information: (1)Key Laboratory for Animal Disease-Resistance Nutrition China Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, Sichuan, China. This study evaluated the effects of dietary distillers' dried grains with solubles (DDGS) levels on nutrient digestibility, meat quality, and intestinal health in meat ducks. In a 28-d feeding trial (Exp. 1), 400 Cherry Valley ducks (average body weight [BW] = 658.73 ± 3.79 g, age = 14 d old) were randomly assigned to five groups receiving 0 (CON), 5%, 10%, 15%, or 20% DDGS. Each treatment had eight replicates (cages) with ten ducks per replicate. A subsequent metabolism trial (Exp. 2) was conducted using the same diets. At 42 d of age, two ducks per replicate were randomly selected and fed diets supplemented with 0.5% titanium dioxide for digestibility determination. Results showed that 20% DDGS significantly reduced the digestibility of gross energy (GE; P = 0.010) and crude protein (CP; P = 0.026) compared to the CON group. As DDGS increased, CP digestibility decreased linearly (P = 0.001) and quadratically (P = 0.049). Serum triglyceride levels were significantly increased in the 20% DDGS group (P = 0.034). For meat quality, DDGS decreased breast muscle lightness (L∗45 min, P = 0.031) and increased yellowness (b∗45 min, P = 0.028). Shear force of breast muscle increased significantly in the 20% DDGS group (P = 0.009) and increased linearly with DDGS (P = 0.015). Histologically, DDGS supplementation decreased muscle fiber density (P = 0.005) and jejunal villus height (P = 0.001), but increased muscle fiber diameter (P = 0.027). Both muscle fiber diameter and density showed significant linear relationships with increasing DDGS levels (P = 0.003 and P < 0.001, respectively). Cecal butyric acid level decreased at 15% and 20% inclusion (P < 0.05), and valeric acid level decreased at 20% inclusion (P < 0.001). Notably, 10% DDGS increased cecal microbial diversity and the abundance of beneficial Prevotellaceae (P < 0.05). In summary, dietary inclusion of 5%-20% DDGS did not adversely affect growth performance, carcass traits, and organ indices in ducks. While higher levels impaired some meat quality traits, 10% DDGS was identified as the optimal level, improving intestinal microbiota without compromising overall production performance. These findings support the partial replacement of corn-soybean meal with DDGS in duck diets. © 2026 The Authors. DOI: 10.1016/j.aninu.2025.11.004 PMCID: PMC12914444 PMID: 41716825 Conflict of interest statement: We declare that we have no financial and personal relationships with other people or organizations that can inappropriately influence our work, and there is no professional or other personal interest of any nature or kind in any product, service and/or company that could be construed as influencing the content of this paper.
20. J Poult Sci. 2026 Feb 12;63:2026006. doi: 10.2141/jpsa.2026006. eCollection 2026. Dampwood Termite Hodotermopsis sjostedti as a Dietary Source for Broiler Chickens. Tsukahara Y(1), Tomonaga N(1), Tasaki E(1)(2), Mitaka Y(1)(3), Tomonaga S(1), Kumagai H(1), Hirooka H(1), Matsuura K(1). Author information: (1)Graduate School of Agriculture, Kyoto University, Kyoto 606-8502, Japan. (2)Department of Life and Food Sciences, Graduate School of Science and Technology, Niigata University, Niigata 950-2181, Japan. (3)Applied Entomology Laboratory, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya 464-8601, Japan. Insects are commanding increasing attention as a sustainable and alternative nutritional source in animal feed. In this study, the safety and nutritional profile of the dampwood termite, Hodotermopsis sjostedti, were evaluated as a novel ingredient in chicken feed. Colonies were lab-reared, and individual termites were collected by carefully crushing the wood, freeze-drying, and grinding. The resulting termite meal contained 65.6% crude protein, 16.0% fat, and 5.2% ash, on a dry matter basis. No minerals were present at toxic concentrations. Two feeding experiments using Ross 308 female broilers were conducted to evaluate the effects of termite meal inclusion. In Experiment 1, 20 chickens (8-d-old) were assigned to four treatments consisting of a commercial diet plus: 5.0% fish meal, 4.5% fish meal + 0.5% termite meal, 2.5% fish meal + 2.5% termite meal, and 5.0% termite meal. In Experiment 2, 18 chickens (9-d-old) were assigned to three diets: control, control + 2.5% termite meal, and control + 2.5% fish meal. Body weight and feed intake were recorded daily, and samples were collected at 21 d of age. Growth performances, organ weights, and blood plasma profiles were generally comparable across treatments. Chickens receiving 5.0% termite meal had greater alanine aminotransferase values, suggesting a potential hepatic burden. No adverse effects on growth, meat, or organ weight were observed. In conclusion, H. sjostedti meal demonstrated strong potential as a novel dietary component for broiler chickens. However, further long-term studies with larger numbers of birds are necessary to ensure a safe and effective use in poultry diets. 2026 Japan Poultry Science Association. DOI: 10.2141/jpsa.2026006 PMCID: PMC12890253 PMID: 41685136 Conflict of interest statement: Conflicts of Interest: The authors declare no conflict of interest.
21. Front Nutr. 2026 Feb 12;13:1722802. doi: 10.3389/fnut.2026.1722802. eCollection 2026. Association between diet intake and trace elements concentrations in couples undergoing in vitro fertilization: a couple-based exploration. Wu C(1)(2), Wang X(2), Su L(2), Gao X(3), Sun Y(3), Tang Y(3), Ju W(3), Liu J(3), Ni F(2), Jiang H(1)(2). Author information: (1)Reproductive Medicine Center, Clinical College of People's Liberation Army Affiliated to Anhui Medical University, Hefei, China. (2)Reproductive Medicine Center, the 901th Hospital of the Joint Logistics Support Force of People's Liberation Army, Hefei, China. (3)School of Public Health, Anhui Medical University, Hefei, Anhui, China. OBJECTIVE: This study aimed to provide guidance for couples in dietary adjustments to optimize trace element concentrations for improved fertility and to offer a reference for formulating precise reproductive health policies. DESIGN: In this prospective cohort study, we analyzed 1,066 couples undergoing in vitro fertilization (IVF) from 2020 to 2023. Dietary intake was assessed using a Food Frequency Questionnaire, and 21 trace elements were measured. Multiple linear regression and factor analysis were used to evaluate associations. SETTING: Hefei City, Anhui Province, China. PARTICIPANTS: A total of 1,066 couples undergoing IVF treatment. RESULTS: In this study, we found significant associations between dietary intake and trace element concentrations in couples undergoing in vitro fertilization (IVF). Results showed that red meat consumption was inversely associated with Thallium (Tl) but positively correlated with Tin (Sn) and Cerium (Ce). Moderate intake of animal offal and processed meats showed significant associations with Aluminum (Al). Moderate sugar-sweetened beverage consumption was inversely linked to Tl levels. Furthermore, the moderate consumption of pickled and fried foods, as well as coffee, exhibited positive correlations with the trace elements Al and Manganese (Mn). Notably, as tea consumption increased, levels of Cobalt (Co), Gallium (Ga), and Strontium (Sr) also exhibited a significant rise. Even after False Discovery Rate (FDR) correction, the positive associations between Al levels and the moderate consumption of animal offal, pickled/fried foods, and coffee remained robust. Additionally, whole grain intake demonstrated a significant positive association with Sn, while tea consumption remained positively correlated with Rubidium (Rb). CONCLUSION: Our study emphasizes the significant impact of dietary intake on trace metal exposure in infertile couples. These insights can guide future research and help couples optimize trace elements through dietary modifications. Copyright © 2026 Wu, Wang, Su, Gao, Sun, Tang, Ju, Liu, Ni and Jiang. DOI: 10.3389/fnut.2026.1722802 PMCID: PMC12935679 PMID: 41769643 Conflict of interest statement: The author(s) declared that this work was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
22. Foods. 2025 Nov 19;14(22):3962. doi: 10.3390/foods14223962. Chicken Liver from Broilers Fed Wheat Germ Expeller: A Source of Minerals and Energy in the Human Diet. Goluch Z(1), Król B(2), Haraf G(1), Okruszek A(1), Sierżant K(2). Author information: (1)Department of Food Technology and Nutrition, Wroclaw University of Economics and Business, 53-345 Wroclaw, Poland. (2)Department of Animal Nutrition and Feed Science, Wroclaw University of Environmental and Life Sciences, 51-631 Wroclaw, Poland. In recent years, edible by-products (including the liver) have gained growing popularity among consumers. That is why the study aimed to assess the energy value, chemical composition, and mineral content of broiler chicken livers after including wheat germ expeller (WGE) in the feed of the broilers. Liver samples were obtained from 32 Ross-308 chickens (8 individuals per treatment). The control group received a basal diet, whereas the remaining treatments (EX5, EX10, and EX15) were characterized by a partial substitution of ground wheat with 5%, 10%, and 15% WGE. The WGE inclusion did not influence liver weight or chemical composition. However, livers from the CT group showed a higher energy value (p ≤ 0.05) than the EX15 group. Sodium and calcium contents were higher in CT and EX5 livers than in EX10 and EX15. No differences were observed in micronutrient levels between groups. A 100 g portion of EX15 livers provided the highest NRV coverage for phosphorus, iron, zinc, and copper, while EX5 livers were richest in calcium and magnesium, and CT livers in manganese. Total Hazard Quotients for Fe, Zn, Cu, and Mn in chicken livers were below 1, suggesting no potential health risk to consumers. These findings indicate that livers, also from WGE-fed broilers, may serve as a valuable dietary source of minerals for people. DOI: 10.3390/foods14223962 PMCID: PMC12651864 PMID: 41300118 Conflict of interest statement: The authors declare no conflicts of interest.
23. Food Chem. 2025 Dec 25;496(Pt 3):146938. doi: 10.1016/j.foodchem.2025.146938. Epub 2025 Nov 3. Vitamin D content of wild-caught traditional foods collected on Nyoongar Country in Western Australia. Dunlop E(1), Nannup N(2), Tilbrook D(3), Michie C(4), Prior C(4), Nannup G(5), Nannup A(6), Farrant B(7), Cunningham J(8), Adorno P(9), Dabos G(9), Jacky J(4), Whyman T(4), McNamara J(4), Bedford L(4), Shepherd CCJ(10), Begley A(8), Neo B(11), Black LJ(12). Author information: (1)Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia; Curtin School of Population Health, Curtin University, Bentley, Western Australia, Australia. (2)The Kids Research Institute Australia, The University of Western Australia, Nedlands, Western Australia, Australia; Indigenous Tours WA, Perth, Western Australia, Australia. (3)Maalinup Aboriginal Gallery, Caversham, Western Australia, Australia. (4)The Kids Research Institute Australia, The University of Western Australia, Nedlands, Western Australia, Australia. (5)Indigenous Tours WA, Perth, Western Australia, Australia. (6)Noongar Boodjar Language Cultural Aboriginal Corporation, Cannington, Western Australia, Australia. (7)The Kids Research Institute Australia, The University of Western Australia, Nedlands, Western Australia, Australia; Ngangk Yira Institute, Murdoch University, Murdoch, Western Australia, Australia. (8)Curtin School of Population Health, Curtin University, Bentley, Western Australia, Australia. (9)National Measurement Institute, Port Melbourne, Victoria, Australia. (10)The Kids Research Institute Australia, The University of Western Australia, Nedlands, Western Australia, Australia; Ngangk Yira Institute, Murdoch University, Murdoch, Western Australia, Australia; Curtin Medical School, Curtin University, Bentley, Western Australia, Australia. (11)Curtin Medical School, Curtin University, Bentley, Western Australia, Australia. (12)Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Victoria, Australia; Curtin School of Population Health, Curtin University, Bentley, Western Australia, Australia. Electronic address: Lucinda.black@deakin.edu.au. Low vitamin D status and intake are prevalent among the Australian population, including Aboriginal and Torres Strait Islander peoples. We hypothesised that some traditional foods could contain vitamin D, and measured vitamin D in foods from Nyoongar Country, Western Australia. Samples of kangaroo, emu, squid/calamari and lobster/crayfish were collected and prepared by Aboriginal people using traditional and contemporary methods. We measured vitamin D3, 25-hydroxyvitamin D3 (25(OH)D3), vitamin D2 and 25(OH)D2 using liquid chromatography-triple quadrupole mass spectrometry. Kangaroo meat and offal were largely devoid of vitamin D (no mean values >0.1 μg/100 g). Vitamin D3 was found in emu meat and calamari/squid (range 0.5-1.0 μg/100 g). No samples contained 25(OH)D3, vitamin D2 or 25(OH)D2 at mean values >0.1 μg/100 g. Modern food composition data can complement traditional knowledges in the promotion of traditional foods for healthy eating and social and emotional wellbeing among Aboriginal and Torres Strait Islander peoples. Copyright © 2025 The Authors. Published by Elsevier Ltd.. All rights reserved. DOI: 10.1016/j.foodchem.2025.146938 PMID: 41197327 [Indexed for MEDLINE] Conflict of interest statement: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have influenced the work reported in this paper. Declaration of interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
24. Nutrients. 2024 Dec 31;17(1):140. doi: 10.3390/nu17010140. Assessing the Nutrient Composition of a Carnivore Diet: A Case Study Model. Goedeke S(1), Murphy T(2), Rush A(3), Zinn C(1). Author information: (1)Human Potential Centre, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland 0632, New Zealand. (2)Nutrition Network, Cape Town, South Africa. (3)Type 1 Diabetes Family Centre, Stirling 6021, WA, Australia. BACKGROUND/OBJECTIVES: The rise in chronic metabolic diseases has led to the exploration of alternative diets. The carnivore diet, consisting exclusively of animal products, has gained attention, anecdotally, for imparting benefit for inflammatory conditions beyond that possible by other restrictive dietary approaches. The aim was to assess the micronutrient adequacy of four versions of the carnivore diet against national nutrient reference values (NRVs). METHODS: This study assessed the nutrient adequacy of the carnivore diet against national NRVs from the Australian National Health and Medical Research Council (NHMRC) and New Zealand Ministry of Health. Four meal plans for hypothetical average Australian adults were developed and analysed using Foodworks.online (Version 1, Xyris Pty Ltd., Brisbane, Australia, 2024), dietary software. Two female and two male plans were included; one set including dairy products and the other set including offal. RESULTS: The carnivore diet met several NRV thresholds for nutrients such as riboflavin, niacin, phosphorus, zinc, Vitamin B6, Vitamin B12, selenium, and Vitamin A, and exceeded the sodium threshold. However, it fell short in thiamin, magnesium, calcium, and Vitamin C, and in iron, folate, iodine and potassium in some cases. Fibre intake was significantly below recommended levels. CONCLUSION: The carnivore diet may offer benefits for managing certain chronic conditions. Whether the metabolic contexts from consuming such a diet facilitates a lower requirement of certain nutrients, or whether it poses risks of micronutrient inadequacies remains to be determined. Tailored nutritional guidance and supplementation strategies are recommended to ensure careful consideration of micronutrient intake to prevent deficiencies. DOI: 10.3390/nu17010140 PMCID: PMC11722875 PMID: 39796574 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest.
25. Open Vet J. 2024 Jan;14(1):154-163. doi: 10.5455/OVJ.2024.v14.i1.14. Epub 2024 Jan 31. Assessment of some toxic elements (Co, Cr, Mn, Se, and As) in muscle, offal, hair, and blood of camels (Camelus dromedaries) and their risk assessment. Meligy AMA(1)(2), El-Ghareeb WR(3)(4), Abdel-Raheem SM(3)(5), Ismail HAA(3)(6), Darwish WS(4), Kandeel M(7)(8), Alfifi AE(3), Al-Shokair SS(1), Hussein MA(4). Author information: (1)Department of Clinical Sciences, College of Veterinary Medicine, King Faisal University, P.O. Box 400, Al-Hofuf 31982, Al-Ahsa, Saudi Arabia. (2)Department of Physiology, PPRI Institute, Agriculture Research Center, Giza, Egypt. (3)Department of Public Health, College of Veterinary Medicine, King Faisal University, P.O. Box 400, Al-Hofuf 31982, Al-Ahsa, Saudi Arabia. (4)Food Control Department, Faculty of Veterinary Medicine, Zagazig University, Zagazig, Egypt. (5)Department of Animal Nutrition and Clinical Nutrition, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt. (6)Department of Food Hygiene, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt. (7)Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al Hofuf, Saudi Arabia. (8)Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt. BACKGROUND: Camel meat tainted with heavy metals or trace elements may pose a health risk to consumers. Heavy metal contamination poses a severe danger due to both their toxicity and bioaccumulation in the food chain. AIM: To estimate the residual levels of heavy metals (Co, Cr, Mn, Se, and As) in muscle, liver, kidney, hair, and serum of three camel breeds (Magaheem, Maghateer, and Wadha) collected from Al-Omran abattoir, Al-Ahsa, Saudi Arabia. METHODS: A total of 225 tissue samples (muscles, liver, kidney, serum, and hair) were taken and analyzed using an Atomic Absorption Spectrophotometer. Health risk assessment was assessed using the guidelines set by the US Environmental Protection Agency. RESULTS: Camel breed significantly (p < 0.05) influences Co, Cr, Mn, and Se accumulation and distribution in organs and muscle; however, arsenic accumulation was not significantly affected (p < 0.05) by camel breeds. The highest values of Co, Cr, Se, and Mn in all examined samples were detected in the liver samples of Maghateer and Magaheem breeds. Furthermore, significant strong positive correlation between serum and liver cobalt, chromium, manganese, and arsenic. The estimated daily intake owing to camel meat consumption was less than the tolerated daily intake. CONCLUSION: Heavy metals were distributed among different breeds of camel. Trace elements (Pb and Cd) in meat and offal were below the international maximum permissible limit. The correlation between samples reflects the role of hair as a good tool for the identification of heavy metal pollution. DOI: 10.5455/OVJ.2024.v14.i1.14 PMCID: PMC11018421 PMID: 38633180 [Indexed for MEDLINE] Conflict of interest statement: The authors declare that there is no conflict of interest.
26. Nutrients. 2024 Jan 30;16(3):405. doi: 10.3390/nu16030405. Maternal Diet Associates with Offspring Bone Mineralization, Fracture Risk and Enamel Defects in Childhood and Influences the Prenatal Effect of High-Dose Vitamin D Supplementation. Kim M(1)(2), Nørrisgaard PE(1), Vahman N(1), Cexus ONF(2), Townsend PA(2), Stokholm J(1)(3), Bønnelykke K(1), Chawes B(1), Brustad N(1). Author information: (1)COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, 2820 Copenhagen, Denmark. (2)Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. (3)Department of Food Science, University of Copenhagen, 1958 Copenhagen, Denmark. We previously demonstrated a beneficial effect of high-dose vitamin D in pregnancy on offspring bone and dental health. Here, we investigated the effect of maternal dietary patterns during pregnancy on the risk of bone fractures, bone mineralization and enamel defects until age 6 years in the offspring. Further, the influence of diet on the effect of high-dose vitamin D was analyzed in the COPSAC2010 mother-child cohort including 623 mother-child pairs. A weighted network analysis on FFQs revealed three specific maternal dietary patterns that associated (Bonferroni p < 0.05) with both offspring bone and dental health. The effect of prenatal high-dose (2800 IU/day) vs. standard-dose (400 IU/day) vitamin D on offspring bone mineral content (adjusted mean difference (aMD): 33.29 g, 95% CI: 14.48-52.09, p < 0.001), bone mineral density (aMD: 0.02 g/cm2 (0.01-0.04), p < 0.001), fracture risk (adjusted incidence rate ratio: 0.36 (0.16-0.84), p = 0.02), and enamel defects in primary (adjusted odds ratio (aOR): 0.13 (0.03-0.58), p < 0.01) and permanent molars (aOR: 0.25; (0.10-0.63), p < 0.01) was most pronounced when mothers had lower intake of fruit, vegetables, meat, eggs, sweets, whole grain, offal and fish. This study suggests that prenatal dietary patterns influence offspring bone and dental development, and should be considered in order to obtain the full benefits of vitamin D to enhance personalized supplementation strategy. DOI: 10.3390/nu16030405 PMCID: PMC10856831 PMID: 38337692 [Indexed for MEDLINE] Conflict of interest statement: All authors declare no potential, perceived, or real conflicts of interest regarding the content of this manuscript.
27. Vopr Pitan. 2023;92(3):93-99. doi: 10.33029/0042-8833-2023-92-3-93-99. Epub 2023 May 17. [The content of zinc and selenium in local food products of Yakutia]. [Article in Russian] Vasilyeva VT(1), Sleptsova TV(1), Lebedeva UM(2), Abramov AF(1), Bappagai EV(3). Author information: (1)M.G. Safronov Yakut Scientific Research Institute of Agriculture - Division of Federal Research Centre "The Yakut Scientific Centre of the Siberian Branch of the Russian Academy of Sciences", 677001, Yakutsk, Russian Federation. (2)M.K. Ammosov North-Eastern Federal University, 677000, Yakutsk, Russian Federation. (3)Federal Research Centre "The Yakut Scientific Centre of the Siberian Branch of the Russian Academy of Sciences", 677980, Yakutsk, Russian Federation. Deficiency of the necessary complex of micronutrients under abnormal nutrition structure creates a problem for the preservation of health and performance of the population. In this regard, it is very relevant to develop a science-based strategy for the consumption of traditional Yakut national food that have a high nutritional value and are able to satisfy the requirements of the human body in micronutrients. The purpose of the research was to investigate the content of selenium and zinc in the local foods which are most commonly consumed by the population of Yakutia. Material and methods. The objects of study were meat (7-9 cuts each) and offal (9-11 species each) of the Yakut cattle breed (2 bulls at the age of 2.5 years), of the Yakut horse foals (3 heads at the age of 6 months), northern domestic deer (3 heads), and whitefish (Coregonus muksun), Yakut crucian carp (Carassius carassius jacuticus), lake minnow [Phoxinus percnurus (Pallas)] (3 kg each). The trace elements, zinc and selenium, were determined by infrared spectroscopy. Results. The greatest amount of zinc in the meat of farm animals was noted in the meat of Yakut cattle (6.8±0.3 mg/100 g) and Yakut horse foals (6.7±0.2 mg/100 g), and the lowest - in the meat of domestic reindeer (1.5±0.1 mg/100 g). In terms of selenium content, the meat of domestic reindeer had the highest indicators (37.0±1.0 μg/100 g), and the meat of Yakut cattle had the lowest (19.0±0.8 μg/100g). The highest concentration of zinc and selenium was found in by-products of reindeer: zinc level in the heart and liver was 12.8 mg/100 g, in the small intestine and rennet - 19.0-20.4 mg/100 g, selenium level in the colon and rennet was 41.0-46.7 μg/100 g. The content of zinc and selenium in the fresh-water muksun belly (2.14±0.08 mg and 45.0±1.8 μg in 100 g) was 32.3-37.2% higher than in the fillet of muksun, and selenium level was 3 fold higher than in the Yakut carp and in the lake minnow. The consumption of 100-200 g of meat or by-products of Yakut cattle, Yakut horse foals, by-products of reindeer or Yakut crucian carp can fully cover the daily requirement of an adult in zinc. The consumption of 200 g of venison or muksun completely covers the daily need for selenium, while the portion of the other studied products contains about half or more of recommended daily intake of this trace element. Conclusion. The data presented in the article show that the population of Yakutia, with a rational diet with local products, can meet the requirements in selenium and zinc in accordance with physiological needs. Copyright© GEOTAR-Media Publishing Group. DOI: 10.33029/0042-8833-2023-92-3-93-99 PMID: 37432712 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest.
28. Int J Cancer. 2022 Dec 1;151(11):1935-1946. doi: 10.1002/ijc.34211. Epub 2022 Aug 4. Diet-wide association study of 92 foods and nutrients and lung cancer risk in the European Prospective Investigation into Cancer and Nutrition study and the Netherlands Cohort Study. Heath AK(1), Muller DC(1), van den Brandt PA(2), Critselis E(3)(4)(5), Gunter M(6), Vineis P(1), Weiderpass E(6), Boeing H(7), Ferrari P(6), Merritt MA(8), Rostgaard-Hansen AL(9), Tjønneland A(9), Overvad K(10), Katzke V(11), Srour B(11), Masala G(12), Sacerdote C(13), Ricceri F(14)(15), Pasanisi F(16), Bueno-de-Mesquita B(17), Downward GS(18)(19), Skeie G(20), Sandanger TM(20), Crous-Bou M(21)(22), Rodríguez-Barranco M(23)(24)(25), Amiano P(26)(27)(28), Huerta JM(25)(29), Ardanaz E(25)(30)(31), Drake I(32), Johansson M(33), Johansson I(34), Key T(35), Papadimitriou N(36), Riboli E(1), Tzoulaki I(1)(37), Tsilidis KK(1)(37). Author information: (1)Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK. (2)Department of Epidemiology, Maastricht University Medical Centre, Maastricht, The Netherlands. (3)Biomedical Research Foundation of the Academy of Athens, Athens, Greece. (4)Department of Nutrition and Dietetics, Harokopio University, Athens, Greece. (5)Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus. (6)International Agency for Research on Cancer, World Health Organization, Lyon, France. (7)Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke, Bergholz-Rehbrücke, Germany. (8)Cancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii, USA. (9)Danish Cancer Society Research Center, Copenhagen, Denmark. (10)Department of Public Health, Aarhus University, Aarhus, Denmark. (11)Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany. (12)Institute of Cancer Research, Prevention and Clinical Network (ISPRO), Florence, Italy. (13)Unit of Cancer Epidemiology, Città della Salute e della Scienza University-Hospital, Turin, Italy. (14)Department of Clinical and Biological Sciences, University of Turin, Turin, Italy. (15)Unit of Epidemiology, Regional Health Service ASL TO3, Grugliasco, Italy. (16)Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Naples, Italy. (17)Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. (18)Institute for Risk Assessment Sciences, Division of Environmental Epidemiology, Utrecht University, Utrecht, The Netherlands. (19)Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands. (20)Department of Community Medicine, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway. (21)Unit of Nutrition and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain. (22)Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. (23)Escuela Andaluza de Salud Pública (EASP), Granada, Spain. (24)Instituto de Investigación Biosanitaria ibs.Granada, Granada, Spain. (25)Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain. (26)Ministry of Health of the Basque Government, Sub-Directorate for Public Health and Addictions of Gipuzkoa, San Sebastián, Spain. (27)Biodonostia Health Research Institute, Epidemiology and Public Health Area, San Sebastián, Spain. (28)CIBER Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III (ISCIII), Madrid, Spain. (29)Department of Epidemiology, Murcia Regional Health Council, IMIB-Arrixaca, Murcia, Spain. (30)Navarra Public Health Institute, Pamplona, Spain. (31)IdiSNA, Navarra Institute for Health Research, Pamplona, Spain. (32)Department of Clinical Sciences in Malmö, Lund University, Malmö, Sweden. (33)Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden. (34)Department of Odontology, Section of Cardiology, Umeå University, Umeå, Sweden. (35)Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK. (36)Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France. (37)Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece. It is unclear whether diet, and in particular certain foods or nutrients, are associated with lung cancer risk. We assessed associations of 92 dietary factors with lung cancer risk in 327 790 participants in the European Prospective Investigation into Cancer and Nutrition (EPIC). Cox regression yielded adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) per SD higher intake/day of each food/nutrient. Correction for multiple comparisons was performed using the false discovery rate and identified associations were evaluated in the Netherlands Cohort Study (NLCS). In EPIC, 2420 incident lung cancer cases were identified during a median of 15 years of follow-up. Higher intakes of fibre (HR per 1 SD higher intake/day = 0.91, 95% CI 0.87-0.96), fruit (HR = 0.91, 95% CI 0.86-0.96) and vitamin C (HR = 0.91, 95% CI 0.86-0.96) were associated with a lower risk of lung cancer, whereas offal (HR = 1.08, 95% CI 1.03-1.14), retinol (HR = 1.06, 95% CI 1.03-1.10) and beer/cider (HR = 1.04, 95% CI 1.02-1.07) intakes were positively associated with lung cancer risk. Associations did not differ by sex and there was less evidence for associations among never smokers. None of the six associations with overall lung cancer risk identified in EPIC were replicated in the NLCS (2861 cases), however in analyses of histological subtypes, inverse associations of fruit and vitamin C with squamous cell carcinoma were replicated in the NLCS. Overall, there is little evidence that intakes of specific foods and nutrients play a major role in primary lung cancer risk, but fruit and vitamin C intakes seem to be inversely associated with squamous cell lung cancer. © 2022 The Authors. International Journal of Cancer published by John Wiley & Sons Ltd on behalf of UICC. DOI: 10.1002/ijc.34211 PMCID: PMC9804326 PMID: 35830197 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no potential conflicts of interest.
29. Environ Monit Assess. 2022 Jun 6;194(7):481. doi: 10.1007/s10661-022-10140-6. Spatio-temporal monitoring of mercury and other stable metal(loid)s and radionuclides in a Croatian terrestrial ecosystem around a natural gas treatment plant. Lazarus M(1), Orct T(2), Sekovanić A(3), Skoko B(3), Petrinec B(3), Zgorelec Ž(4), Kisić I(4), Prevendar Crnić A(5), Jurasović J(2), Srebočan E(5). Author information: (1)Analytical Toxicology and Mineral Metabolism Unit, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000, Zagreb, Croatia. mlazarus@imi.hr. (2)Analytical Toxicology and Mineral Metabolism Unit, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000, Zagreb, Croatia. (3)Radiation Protection Unit, Institute for Medical Research and Occupational Health, Ksaverska c. 2, 10000, Zagreb, Croatia. (4)Department of General Agronomy, Division of Agroecology, Faculty of Agriculture, University of Zagreb, Svetošimunska cesta 25, 10000, Zagreb, Croatia. (5)Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, University of Zagreb, Heinzelova 55, 10000, Zagreb, Croatia. The natural gas industry bears a certain contamination risk to human and biota due to, among others, mercury, arsenic, and naturally occurring radioactive material content in gas. We tracked multiple stabile metal(loid)s and radionuclides within the natural gas treatment plant Molve, Croatia, ecosystem during the last decade through a comprehensive monitoring of soil, earthworms, moss, livestock (blood, milk, hair, urine, and feces from cows), and wildlife animals (brain, muscle, liver, and kidney of European hare and pheasant). The level of mercury and other stable metal(loid)s has shown temporal variation, but without an obvious trend. The found spatial differences in soil and earthworms were based on the differing soil characteristics of the sampled locations and exceeded the maximal allowable concentration of arsenic and zinc for agricultural soil. The status of essential copper, selenium, and zinc in cows, hares, and pheasants inclined towards deficiency. The measured stable metal(loid) levels in soil and animal samples were generally in the same range of values reported in earlier decades from the same area or non-polluted areas across Europe. The consumption of local cow and game products (e.g., milk, meat) can be considered safe for human health, although game offal is advised to be avoided as a food item due to the low risk of lead and cadmium's adverse effects. Although the activity concentrations of some radionuclides in moss were higher than reported for pristine areas, transfer from soil to moss was assessed as average (except for lead-210). Radiological risk to human and biota around the gas treatment plant Molve was estimated as negligible. © 2022. The Author(s), under exclusive licence to Springer Nature Switzerland AG. DOI: 10.1007/s10661-022-10140-6 PMID: 35668141 [Indexed for MEDLINE]
30. Food Chem. 2020 Dec 15;333:127447. doi: 10.1016/j.foodchem.2020.127447. Epub 2020 Jul 4. Collaborative study: Quantification of total folate in food using an efficient single-enzyme extraction combined with LC-MS/MS. Ložnjak Švarc P(1), Oveland E(2), Strandler HS(3), Kariluoto S(4), Campos-Giménez E(5), Ivarsen E(6), Malaviole I(7), Motta C(8), Rychlik M(9), Striegel L(10), Jakobsen J(11). Author information: (1)National Food Institute, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark. Electronic address: petlon@food.dtu.dk. (2)Institute of Marine Research, P. O. Box 1870, Nordnes, N-5817 Bergen, Norway. Electronic address: Eystein.Oveland@hi.no. (3)Swedish Food Agency, P.O. Box 622, 751 26 Uppsala, Sweden. Electronic address: HannaSara.Strandler@slv.se. (4)University of Helsinki, Department of Food and Nutrition, Agnes Sjöbergin katu 2, FI-00790 Helsinki, Finland. Electronic address: susanna.kariluoto@helsinki.fi. (5)Nestle Research, Route du Jorat 57, Vers-chez-les-Blanc, 1000 Lausanne 26, Switzerland. Electronic address: esther.campos-gimenez@rdls.nestle.com. (6)Eurofins Vitamin Testing, Ladelundvej 85, 6600 Vejen, Denmark. Electronic address: EliseIvarsen@eurofins.dk. (7)Laboratoire Aquanal, 5 rue Marcel Dassault, 33600 Pessac, France. Electronic address: imalaviole@aquanal.fr. (8)National Health Institute, Dr. Ricardo Jorge, Av. Padre Cruz, 1649-016 Lisbon, Portugal. Electronic address: carla.motta@insa.min-saude.pt. (9)Chair of Analytical Food Chemistry, Technical University of Munich, Max-von-Imhof Forum 2, DE-85354 Freising, Germany; Centre for Nutrition and Food Sciences, University of Queensland, St Lucia QLD 4069, Australia. Electronic address: michael.rychlik@tum.de. (10)Chair of Analytical Food Chemistry, Technical University of Munich, Max-von-Imhof Forum 2, DE-85354 Freising, Germany. Electronic address: lisa.striegel@tum.de. (11)National Food Institute, Technical University of Denmark, Kemitorvet, 2800 Kgs. Lyngby, Denmark. Electronic address: jeja@food.dtu.dk. Quantification of the specific folate vitamers to estimate total folate in foods is not standardized. A collaborative study, including eight European laboratories, was conducted in order to determine the repeatability and reproducibility of the method for folate quantification in foods using the plant-origin γ-glutamyl hydrolase as part of the extraction procedure. The seven food samples analyzed represent the food groups; fruits, vegetables, dairy products, legumes, offal, fish, and fortified infant formula. The homogenization step was included, and six folate vitamers were analyzed using LC-MS/MS. Total folate content, expressed as folic acid equivalent, was 17-490 μg/100 g in all samples. Horwitz ratio values were within the acceptable range (0.60-1.94), except for fish. The results for fortified infant formula, a certified reference material (NIST 1869), confirmed the trueness of the method. The collaborative study is part of a standardization project within the Nordic Committee on Food Analysis (NMKL). Copyright © 2020 Elsevier Ltd. All rights reserved. DOI: 10.1016/j.foodchem.2020.127447 PMID: 32688304 [Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
31. Food Res Int. 2020 Jun;132:109123. doi: 10.1016/j.foodres.2020.109123. Epub 2020 Feb 21. Workflow towards the generation of bioactive hydrolysates from porcine products by combining in silico and in vitro approaches. Bechaux J(1), Ferraro V(2), Sayd T(2), Chambon C(3), Le Page JF(4), Drillet Y(4), Gatellier P(2), Santé-Lhoutellier V(5). Author information: (1)INRAE, UR 370, Qualité des produits animaux (QuaPA), Biochimie des protéines du muscle (BPM), Site de Theix, 63122 Saint Genès Champanelle, France; Cooperl Innovation, BU Ingrédients, Site de Lamballe, 22400 Lamballe, France. (2)INRAE, UR 370, Qualité des produits animaux (QuaPA), Biochimie des protéines du muscle (BPM), Site de Theix, 63122 Saint Genès Champanelle, France. (3)INRAE, UR 370, Qualité des produits animaux (QuaPA), Plateforme exploration du métabolisme (PFEM), Site de Theix, 63122 Saint Genès Champanelle, France. (4)Cooperl Innovation, BU Ingrédients, Site de Lamballe, 22400 Lamballe, France. (5)INRAE, UR 370, Qualité des produits animaux (QuaPA), Biochimie des protéines du muscle (BPM), Site de Theix, 63122 Saint Genès Champanelle, France. Electronic address: veronique.sante-lhoutellier@inra.fr. Food-derived bioactive peptides have generated an increasing interest in the field of health and well-being research. They can act either against the metabolic syndrome, participate in regulating the oxidation balance or act on the immune system. The aim of this study is to develop a workflow to generate bioactive peptides from three porcine offals namely, heart, liver, and lung and one muscle the Longissimus Dorsi, by combining in silico and in vitro approaches. Bioinformatics tools (e.i. BIOPEP and Uniprot) permitted to orientate the choice of enzymes for generating abundant bioactive peptides from the four studied porcine products. With papain and subtilisin, the main bioactivities potentially released were ACE inhibitors, DPP4 inhibitors and antioxidant peptides. An in vitro validation study using papain and subtilisin demonstrated high DPP4 inhibitors and antioxidant bioactivities for the generation of peptides. This work allowed: i) the identification of all proteins that composed porcine heart, liver, lung and LD muscle that could be useful for the scientific community, ii) the development of a workflow to select most abundant proteins in a product while considering abundance factors and iii) the potential of porcine meat and offals to generate DPP4 inhibitors and antioxidant peptides. However, there is still a need in developing new tools in order to face limitations of mass spectrometry for the identification of peptides with less than six amino acids. Such a work may contribute to the development of the circular economy and the innovative creation of value-added products from animal production. Copyright © 2020 Elsevier Ltd. All rights reserved. DOI: 10.1016/j.foodres.2020.109123 PMID: 32331690 [Indexed for MEDLINE] Conflict of interest statement: Declaration of Competing Interest There are no conflicts of interest.
32. J Food Sci. 2020 Feb;85(2):493-499. doi: 10.1111/1750-3841.15014. Epub 2020 Jan 27. Concentrations of heavy metals in muscle and edible offal of pork in Nanjing city of China and related health risks. Pei F(1), Wang Y(1), Fang Y(1), Li P(1), Yang W(1), Ma N(1), Ma G(1), Hu Q(1). Author information: (1)College of Food Science and Engineering/Collaborative Innovation Center for Modern Grain Circulation and Safety/Key Laboratory of Grains and Oils Quality Control and Processing, Nanjing Univ. of Finance and Economics, Nanjing, 210023, China. The concentrations of heavy metals, such as chromium (Cr), arsenic (As), cadmium (Cd), mercury (Hg), and lead (Pb), in different muscles and edible offal of consumed pork from the city of Nanjing and related health risks were evaluated. The results showed that the detected Hg concentrations from 6 of 80 samples exceeded the maximum allowable concentration (GB 2762-2017). Moreover, most of the edible offal, especially the kidneys, contained more heavy metals than the other parts, although the concentrations among the samples were significantly different (P < 0.05). In addition, the health risk evaluation revealed that the estimated daily intake of all the samples was far below the recommended limit, and all the target hazard quotients and total target hazard quotients were less than 1, which is considered safe for human health. Nevertheless, the Hg concentrations over the acceptable limit should receive sufficient attention, considering the long-term consumption of pork. PRACTICAL APPLICATION: Currently, no reports have been available on the heavy metal assessment of pork, though pork is widely consumed in many non-Muslim communities. In this study, the concentrations of heavy metals in different muscles and edible offal of consumed pork were determined and their related health risks were evaluated. This study will provide a significant reference to understand the quality and safety of pork in China or other similar developing countries. © 2020 Institute of Food Technologists®. DOI: 10.1111/1750-3841.15014 PMID: 31985835 [Indexed for MEDLINE]
33. Zoonoses Public Health. 2019 Sep;66(6):562-578. doi: 10.1111/zph.12611. Epub 2019 Jun 9. Infection, colonization and shedding of Campylobacter and Salmonella in animals and their contribution to human disease: A review. Rukambile E(1)(2)(3)(4), Sintchenko V(3)(5), Muscatello G(1), Kock R(6), Alders R(3)(7)(8). Author information: (1)School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, New South Wales, Australia. (2)Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia. (3)Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, New South Wales, Australia. (4)Tanzania Veterinary Laboratory Agency, Dar es Salaam, Tanzania. (5)Centre for Infectious Diseases and Microbiology-Public Health, Westmead Hospital and New South Wales Health Pathology, Sydney, New South Wales, Australia. (6)The Royal Veterinary College, University of London, London, UK. (7)Kyeema Foundation, Brisbane, Queensland, Australia. (8)Centre on Global Health Security, Chatham House, London, UK. Livestock meat and offal contribute significantly to human nutrition as sources of high-quality protein and micronutrients. Livestock products are increasingly in demand, particularly in low- and middle-income settings where economies are growing and meat is increasingly seen as an affordable and desirable food item. Demand is also driving intensification of livestock keeping and processing. An unintended consequence of intensification is increased exposure to zoonotic agents, and a contemporary emerging problem is infection with Campylobacter and Salmonella spp. from livestock (avian and mammalian), which can lead to disease, malabsorption and undernutrition through acute and chronic diarrhoea. This can occur at the farm, in households or through the food chain. Direct infection occurs when handling livestock and through bacteria shed into the environment, on food preparation surfaces or around the house and surroundings. This manuscript critically reviews Campylobacter and Salmonella infections in animals, examines the factors affecting colonization and faecal shedding of bacteria of these two genera as well as risk factors for human acquisition of the infection from infected animals or environment and analyses priority areas for preventive actions with a focus on resource-poor settings. © 2019 Blackwell Verlag GmbH. DOI: 10.1111/zph.12611 PMID: 31179637 [Indexed for MEDLINE]
34. Neuroimage. 2019 Oct 1;199:281-288. doi: 10.1016/j.neuroimage.2019.05.066. Epub 2019 May 30. Specific nutrient patterns are associated with higher structural brain integrity in dementia-free older adults. Prinelli F(1), Fratiglioni L(2), Kalpouzos G(3), Musicco M(4), Adorni F(4), Johansson I(5), Marseglia A(3), Xu W(6). Author information: (1)Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18A Floor 10, SE-171 65, Solna, Stockholm, Sweden; Institute of Biomedical Technologies - National Research Council, Via Fratelli Cervi 93, 20090, Segrate, Milan, Italy. Electronic address: federica.prinelli@ki.se. (2)Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18A Floor 10, SE-171 65, Solna, Stockholm, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden. (3)Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18A Floor 10, SE-171 65, Solna, Stockholm, Sweden. (4)Institute of Biomedical Technologies - National Research Council, Via Fratelli Cervi 93, 20090, Segrate, Milan, Italy. (5)Department of Odontology, Umeå University, Vårdvetarhuset, 901 85, Umeå, Sweden. (6)Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Tomtebodavägen 18A Floor 10, SE-171 65, Solna, Stockholm, Sweden; Department of Epidemiology & Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China. Electronic address: xuweili@tmu.edu.cn. Optimal nutrition may play a beneficial role in maintaining a healthy brain. However, the relationship between nutrient intake and brain integrity is largely unknown. We investigated the association of specific nutrient dietary patterns with structural characteristics of the brain. Within the population-based Swedish National study on Aging and Care-Kungsholmen (SNAC-K), a cross-sectional study of 417 dementia-free participants aged ≥60 years who underwent structural magnetic resonance imaging (MRI) scans during 2001-2003, was carried-out. Data on dietary intake were collected using a food frequency questionnaire, from which intake of 21 nutrients was estimated. By principal component analysis, five nutrient patterns were extracted: (1) NP1 was characterized by fiber, vitamin C, E, β-carotene, and folate [Fiber&Antioxidants], (2) NP2 by eicosapentaenoic (EPA, 20:5 ω-3) and docosahexaenoic (DHA, 22:6 ω-3) polyunsaturated fatty acids (PUFAs), proteins, cholesterol, vitamin B3, B12, and D [long chain (LC) ω-3PUFAs&Proteins], (3) NP3 by α-linoleic (18:2 ω-6) and α-linolenic (18:3 ω-3) PUFAs, monounsaturated fatty acids (MUFAs), and vitamin E [MUFAs&ω-3,6PUFAs], (4) NP4 by saturated fatty acids (SFAs), trans fats, MUFAs, and cholesterol [SFAs&Trans fats], (5) NP5 by B-vitamins, retinol, and proteins [B-Vitamins&Retinol]. Nutrient patterns scores were tertiled with the lowest tertile as reference, and were related to total brain volume (TBV) and white matter hyperintensities volume (WMHV) using linear regression models adjusting for potential confounders. In the multi-adjusted model, compared to the lowest intake for each pattern, the highest intake of NP1 (β = 11.11, P = 0.009), NP2 (β = 7.47, P = 0.052), and NP3 (β = 10.54, P = 0.005) was associated with larger TBV whereas NP5 was related to smaller TBV (β = -12.82, P = 0.001). The highest intake of NP1 was associated with lower WMHV (β = -0.32, P = 0.049), whereas NP4 was associated with greater WMHV (β = 0.31, P = 0.036). In sum, our results suggest that the identified brain-health specific nutrient combinations characterized by higher intake of fruit, vegetables, legumes, olive and seed oils, fish, lean red meat, poultry and low in milk and dairy products, cream, butter, processed meat and offal, were strongly associated with greater brain integrity among older adults. Copyright © 2019 Elsevier Inc. All rights reserved. DOI: 10.1016/j.neuroimage.2019.05.066 PMID: 31154046 [Indexed for MEDLINE]
35. Biol Trace Elem Res. 2019 Oct;191(2):338-347. doi: 10.1007/s12011-019-1637-6. Epub 2019 Feb 6. Dietary Intake of Cadmium, Chromium, Copper, Nickel, and Lead through the Consumption of Meat, Liver, and Kidney and Assessment of Human Health Risk in Birjand, Southeast of Iran. Zeinali T(1), Salmani F(2), Naseri K(3). Author information: (1)Social Determinants of Health Research Center, School of Health, Birjand University of Medical Sciences, Birjand, Iran. (2)Social Determinants of Health Research Center, Department of Epidemiology and Biostatistics, School of Health, Birjand University of Medical Sciences, Birjand, Iran. (3)Medical Toxicology and Drug Abuse Research center (MTDRC), School of Medicine, Birjand University of Medical Sciences, Birjand, Iran. naserik@bums.ac.ir. This study aimed to evaluate the mean concentration of cadmium (Cd), chromium (Cr), copper (Cu), nickel (Ni), and lead (Pb) in the meat and offal of cow and sheep. Also, the estimated daily intake (EDI) and health risk of these metals were calculated. Analysis of metals was undertaken by the use of an inductively coupled plasma-optic emission spectroscopy (ICP-OES). All samples were contaminated with all metals. Principal component analysis (PCA) showed a clear differentiation of cow and sheep in both the kidney and liver samples. In the liver and kidney, level of Cd, Cu, and Pb were positively correlated. The highest target hazard quotients (THQs) were calculated for Pb. Cd level in cow kidney had the highest carcinogenic rate (CR). Although, hazard index (HI) was lower than one, consumption of muscle especially in children should be noticed in both national and international consumers due to higher level of HI. DOI: 10.1007/s12011-019-1637-6 PMID: 30729389 [Indexed for MEDLINE]
36. Front Nutr. 2018 Jun 14;5:50. doi: 10.3389/fnut.2018.00050. eCollection 2018. Global Provisioning of Red Meat for Flexitarian Diets. Hicks TM(1), Knowles SO(2), Farouk MM(1). Author information: (1)Food Assurance and Meat Quality, Food and Bio-based Products Group, AgResearch Limited, Hamilton, New Zealand. (2)Food Nutrition and Health, Food and Bio-based Products Group, AgResearch Limited, Palmerston North, New Zealand. Although not always labeled as such, flexitarianism is the default lifestyle for much of the world, whereby meals based on plant materials provide the bulk of people's calories. The rich nutrition of meat and animal products is often the lynchpin of these diets, even when only consumed occasionally. It provides forms and concentrations of essential proteins, lipids, and micronutrients that are otherwise scarce. However, the production of this meat is resource intensive. It requires large quantities of arable land and water, and typically has lower conversion efficiency of farm inputs to edible outputs compared with crops, poultry, aquaculture, dairy, and eggs. An additional complication is that the quantity of ancillary products produced during slaughterhouse operations is large and underutilized. Each year, approximately 190 million metric tons (MMT) of red meat, including pork, lamb, sheep, veal, beef, and goats are produced globally, half of which will be consumed by less than 25% of the population living in developed countries. With demand for meat expected to exceed 376 MMT by 2030, an increase in the adoption of plant-based diets presents an opportunity for the world to re-evaluate how meat can be sustainably produced, with greater emphasis on animal welfare, nutritional value, product safety, better utilization, and distribution channels. In this article we consider the role meat plays in the modern diet, its production and consumption, opportunities to improve utilization of the animal, the benefits of incorporating a diverse range of red meat into diets, and the strategies that the meat industry should consider in response to flexitarianism. DOI: 10.3389/fnut.2018.00050 PMCID: PMC6010543 PMID: 29963555
37. Food Res Int. 2018 Feb;104:48-58. doi: 10.1016/j.foodres.2016.11.038. Epub 2016 Dec 1. Targeting the pains of food insecurity and malnutrition among internally displaced persons with nutrient synergy and analgesics in organ meat. Fayemi PO(1), Muchenje V(2), Yetim H(3), Ahhmed A(3). Author information: (1)Department of Livestock and Pasture Science, Faculty of Science & Agriculture, University of Fort Hare, Alice 5700, South Africa; Food Engineering Department, Faculty of Engineering, Erciyes University, Kayseri 38039, Turkey. Electronic address: pfayemi@ufh.ac.za. (2)Department of Livestock and Pasture Science, Faculty of Science & Agriculture, University of Fort Hare, Alice 5700, South Africa. (3)Food Engineering Department, Faculty of Engineering, Erciyes University, Kayseri 38039, Turkey. Living with pain is one of the distressing effects of food insecurity and malnutrition among millions of internally displaced persons (IDPs) worldwide. Vulnerability to emotional pain, metabolic imbalance, chronic illnesses and non-communicable diseases by IDPs are associated with stressed livelihood and restricted access to balanced diets in their camps. Tackling the complexity of issues related to internal displacement is challenging as 45% are globally trapped in protracted conditions. In this review, a diet-based intervention is proposed considering the potential benefits of nutrient synergy and analgesic constituents in organ meat. Providing an affordable, value added and well packaged nutrient dense diet is suggested to meet daily protein and micronutrient requirements from organ meat. Also, unlocking health-promoting bioactive substances and analgesics in restructured organ meat product is proposed as personalized dietary remedy to exert opioid bioactivity in food matrix. Exploiting the nutrient synergy of this animal by-product will not only improve the nutritional status or wellbeing but also raise the composite score of dietary diversity or food security index among IDPs by 2030. Copyright © 2016. Published by Elsevier Ltd. DOI: 10.1016/j.foodres.2016.11.038 PMID: 29433783 [Indexed for MEDLINE]
38. J Nutr Sci Vitaminol (Tokyo). 2017;63(2):85-95. doi: 10.3177/jnsv.63.85. Vitamin D Deficiency and Associated Factors in Patients with Mental Disorders Treated in Routine Practice. Ristic S(1), Zivanovic S(2), Milovanovic DR(3), Janjic V(4), Djokovic D(4), Jovicevic A(1), Pirkovic MS(5), Kocic S(6). Author information: (1)Institute for Oncology and Radiology of Serbia. (2)Department of Medicine, Faculty of Hotel Management and Tourism, University of Kragujevac. (3)Department of Clinical Pharmacology, Clinical Centre "Kragujevac", Faculty of Medical Science, University of Kragujevac. (4)Clinic for Psychiatry, Clinical Centre "Kragujevac", Faculty of Medical Sciences, University of Kragujevac. (5)Department of Biochemistry, Faculty of Medical Sciences, University of Kragujevac. (6)Public Health Institute Kragujevac, Faculty of Medical Sciences, University of Kragujevac. This research aimed to investigate factors associated with vitamin D deficiency and to provide data about its prevalence in patients suffering from different psychiatric illnesses. The study had a cross-sectional design and it included 220 patients of both genders, aged from 19-81 y, with a wide range of mental disorders (F00-F89), and treated in routine ambulatory and hospital practice. The researchers collected data from three sources: medical records, a study questionnaire and biochemical analysis of patients' serum samples (concentration of vitamin D measured as 25(OH)D, calcium, phosphorus, magnesium, sodium and potassium). Data were analyzed using descriptive statistics, methods for hypothesis testing and binary logistic regression, at the p≤0.05 level. A total of 140 patients (64%) had a deficiency of vitamin D (<12 ng/mL), and 45 (20%) had inadequate vitamin D serum levels (12-20 ng/mL), while 35 (16%) had sufficient vitamin D serum concentrations (>20 ng/mL). Among variables related to demographics, life style habits, mental illness, comorbid disorders and drugs, two of them, female gender (odds ratio (OR)=2.5, 95% confidence interval (CI)=1.3-4.9, p=0.006) and using clozapine (OR=15.6, 95% CI 1.7-144.7, p=0.02), were significantly associated with vitamin D deficiency. Physical activity (OR= 0.4, 95% CI 0.2-0.9, p=0.02), exercising (OR=0.2, 95% CI <0.1-0.7, p=0.02) and offal in the diet (OR=0.5, 95% CI 0.3-0.9, p=0.03) significantly aggregated in the patients who had a 25(OH)D serum concentration above the deficiency cut-off level. Patients with mental disorders are at high risk for vitamin D deficiency, particularly females and clozapine users as well as those having no adequate physical activity or dietary habits. DOI: 10.3177/jnsv.63.85 PMID: 28552881 [Indexed for MEDLINE]
39. Talanta. 2017 Jul 1;169:123-129. doi: 10.1016/j.talanta.2017.03.071. Epub 2017 Mar 24. Quantification of copper content with laser induced breakdown spectroscopy as a potential indicator of offal adulteration in beef. Casado-Gavalda MP(1), Dixit Y(2), Geulen D(3), Cama-Moncunill R(2), Cama-Moncunill X(2), Markiewicz-Keszycka M(2), Cullen PJ(4), Sullivan C(2). Author information: (1)School of Food Science and Environmental Health, Dublin Institute of Technology, Dublin 1, Ireland. Electronic address: maria.casado@dit.ie. (2)School of Food Science and Environmental Health, Dublin Institute of Technology, Dublin 1, Ireland. (3)Department of Food Technology, Trier University of Applied Sciences, Trier, Germany. (4)School of Food Science and Environmental Health, Dublin Institute of Technology, Dublin 1, Ireland; School of Chemical Engineering, University of New South Wales, Sydney, Australia. Laser induced breakdown spectroscopy (LIBS) is an emerging technique in the field of food analysis which provides various advantages such as minimal sample preparation, chemical free, rapid detection, provision of spatial information and portability. In this study, LIBS was employed for quantitative analysis of copper content in minced beef samples spiked with beef liver over three independent batches. Copper content was determined with graphite furnace atomic absorption spectroscopy (GFAAS) in order to obtain reference values for modelling. Partial least square regression (PLSR) was performed to build a calibration and validation model. A calibration model with a high Rcv2 of 0.85 and a RMSECV of 43.5ppm was obtained, confirming a good fit for the model. The validation model showed a good prediction accuracy with a high Rp2 of 0.85 and RMSEP of 36.8ppm. Moreover, on a further study to evaluate the spatial capabilities, LIBS was able to successfully map copper content within a pellet, indicating the suitability of LIBS to provide spatial information and therefore potential use on heterogeneous samples. Overall, it can be concluded that LIBS combined with chemometrics demonstrates potential as a quality monitoring tool for the meat processing industry. Copyright © 2017 Elsevier B.V. All rights reserved. DOI: 10.1016/j.talanta.2017.03.071 PMID: 28411800 [Indexed for MEDLINE]
40. Vet World. 2017 Feb;10(2):262-269. doi: 10.14202/vetworld.2017.262-269. Epub 2017 Feb 28. Evaluation of some heavy metals residues in batteries and deep litter rearing systems in Japanese quail meat and offal in Egypt. Ahmed AM(1), Hamed DM(2), Elsharawy NT(3). Author information: (1)Department of Food Hygiene, Faculty of Veterinary Medicine, Suez Canal University, Egypt. (2)Department of Poultry and Rabbit Medicine, Faculty of Veterinary Medicine, Suez Canal University, Egypt. (3)Department of Food Hygiene, Faculty of Veterinary Medicine, New Valley, Assiut University, Egypt. AIM: The main objectives of this study were for comparing the effect of batteries and deep litter rearing systems of domesticated Japanese quail, Coturnix coturnix japonica, on the concentration levels of cadmium, copper, lead, and zinc from the quail meat and offal in Ismailia, Egypt. MATERIALS AND METHODS: A total of 40 quail meat and their offal samples were randomly collected from two main quail rearing systems: Battery (Group I) and deep litter system (Group II) for determination of concentration levels of cadmium, copper, lead, and zinc. In addition, 80 water and feed samples were randomly collected from water and feeders of both systems in the Food Hygiene Laboratory, Faculty of Veterinary Medicine, Suez Canal University for heavy metals determination. RESULTS: The mean concentration levels of cadmium, copper, lead, and zinc in Group I were 0.010, 0.027, 1.137, and 0.516 ppm and for Group II were 0.093, 0.832, 0.601, and 1.651 ppm, respectively. The mean concentration levels of cadmium, copper, lead, and zinc in quail feed in Group I were 1.114, 1.606, 5.822, and 35.11 ppm and for Group II were 3.010, 2.576, 5.852, and 23.616 ppm, respectively. The mean concentration levels of cadmium, copper, lead, and zinc in quail meat for Group I were 0.058, 5.902, 10.244, and 290 ppm and for Group II were 0.086, 6.092, 0.136, and 1.280 ppm, respectively. The mean concentration levels of cadmium, copper, lead, and zinc for liver samples in Group I were 0.15, 8.32, 1.05, and 3.41 ppm and for Group II were 0.13, 8.88, 0.95, and 4.21 ppm, respectively. The mean concentration levels of cadmium, copper, lead, and zinc in kidney samples for the Group I were 0.24, 4.21, 1.96, and 4.03 ppm and for Group II were 0.20, 5.00, 1.56, and 3.78 ppm, respectively. Kidney had the highest concentration levels of heavy metals followed by liver then muscles. The highest concentration levels of copper were observed in liver samples. The order of the levels of these trace elements obtained from the four different quail organs is Ca > Pb > Zn > Cu. Lead and cadmium concentration levels in quail meat samples were exceeded the Egyptian standardization limits and suggesting a health threat from lead and cadmium to the quail consumers. CONCLUSION: Battery rearing system is more hygienic than deep litter system from the point of heavy metals pollution of water and feeds of quail. Feed samples from battery system had means concentration levels of lead not significantly higher (p>0.05) than those samples from deep litter system. Meanwhile, water samples from battery system had means concentration levels of cadmium, copper, and zinc significantly higher (p>0.05) than those samples from deep litter system. Quail may carry health risks to consumers. DOI: 10.14202/vetworld.2017.262-269 PMCID: PMC5352855 PMID: 28344413
⚠️ 면책 고지
이 정보는 일반 교육 목적이며 의료 진단/처방을 대체하지 않습니다.