멜라토닌 (초저용량 0.3mg)

A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED.

1. Am J Emerg Med. 2017 Aug;35(8):1095-1100. doi: 10.1016/j.ajem.2017.03.004. Epub 2017 Mar 3. A prospective randomized, double-dummy trial comparing IV push low dose ketamine to short infusion of low dose ketamine for treatment of  pain in the ED. Motov S(1), Mai M(2), Pushkar I(2), Likourezos

Pharmacokinetics and pharmacodynamics of two different landiolol formulations in a healthy Caucasian group.

2. Eur J Pharm Sci. 2016 Sep 20;92:64-73. doi: 10.1016/j.ejps.2016.06.022. Epub 2016 Jun 29. Pharmacokinetics and pharmacodynamics of two different landiolol formulations in a healthy Caucasian group. Krumpl G(1), Ulc I(2), Trebs M(3), Kadlecová P(4), Hodisch J(3). Author information: (1)MRN Me

A Phase 1 clinical trial of a DNA vaccine for Venezuelan equine encephalitis delivered by intramuscular or intradermal electroporation.

3. Vaccine. 2016 Jun 30;34(31):3607-12. doi: 10.1016/j.vaccine.2016.04.077. Epub 2016 May 17. A Phase 1 clinical trial of a DNA vaccine for Venezuelan equine encephalitis delivered by intramuscular or intradermal electroporation. Hannaman D(1), Dupuy LC(2), Ellefsen B(1), Schmaljohn CS(3). Auth

Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial.

4. Am J Emerg Med. 2015 Mar;33(3):402-8. doi: 10.1016/j.ajem.2014.12.058. Epub 2015 Jan 7. Low-dose ketamine vs morphine for acute pain in the ED: a randomized controlled trial. Miller JP(1), Schauer SG(2), Ganem VJ(3), Bebarta VS(4). Author information: (1)Department of Emergency Medicine, San

Efficacy and safety of high dose versus low dose furosemide with or without dopamine infusion: the Dopamine in Acute Decompensated Heart Failure II (DAD-HF II) trial.

5. Int J Cardiol. 2014 Mar 1;172(1):115-21. doi: 10.1016/j.ijcard.2013.12.276. Epub 2014 Jan 10. Efficacy and safety of high dose versus low dose furosemide with or without dopamine infusion: the Dopamine in Acute Decompensated Heart Failure II (DAD-HF II) trial. Triposkiadis FK(1), Butler J(2)

Use of low-dose clinical pharmacodynamic and pharmacokinetic data to establish an occupational exposure limit for dapagliflozin, a potent inhibitor of the renal sodium glucose co-transporter 2.

6. Regul Toxicol Pharmacol. 2013 Oct;67(1):89-97. doi: 10.1016/j.yrtph.2013.07.002. Epub 2013 Jul 11. Use of low-dose clinical pharmacodynamic and pharmacokinetic data to establish an occupational exposure limit for dapagliflozin, a potent inhibitor of the renal sodium glucose co-transporter 2.

Clinical results from a randomized, double-blind, dose-ranging study of pantoprazole in children aged 1 through 5 years with symptomatic histologic or erosive esophagitis.

7. Clin Pediatr (Phila). 2010 Sep;49(9):852-65. doi: 10.1177/0009922810369253. Epub 2010 Jun 3. Clinical results from a randomized, double-blind, dose-ranging study of pantoprazole in children aged 1 through 5 years with symptomatic histologic or erosive esophagitis. Baker R(1), Tsou VM, Tung J

Effects of low-dose, continuous combined hormone replacement therapy on sleep in symptomatic postmenopausal women.

8. Maturitas. 2005 Feb 14;50(2):91-7. doi: 10.1016/j.maturitas.2004.04.006. Effects of low-dose, continuous combined hormone replacement therapy on sleep in symptomatic postmenopausal women. Gambacciani M(1), Ciaponi M, Cappagli B, Monteleone P, Benussi C, Bevilacqua G, Vacca F, Genazzani AR. A

High- versus low-dose ketamine for analgesia in older adults in the emergency department.

9. Am J Emerg Med. 2024 Dec;86:120-124. doi: 10.1016/j.ajem.2024.10.015. Epub 2024 Oct 12. High- versus low-dose ketamine for analgesia in older adults in the emergency department. Ginsburg AD(1), Heaton HA(2), Beaudrie-Nunn A(3), E Silva LOJ(4), Canterbury E(5), Brown CS(6), Palmer AK(7), Cole

Buprenorphine reduces somatic withdrawal in a mouse model of early-life morphine exposure.

10. Drug Alcohol Depend. 2023 Jul 1;248:109938. doi: 10.1016/j.drugalcdep.2023.109938. Epub 2023 May 22. Buprenorphine reduces somatic withdrawal in a mouse model of early-life morphine exposure. Lepore G(1), Morley-McLaughlin T(2), Davidson N(2), Han C(2), Masese C(2), Reynolds G(2), Saltz V(2

Benign thyroid nodules respond to a single administration of 0.3mg recombinant human thyrotropin with highly variable volume increase.

11. Front Endocrinol (Lausanne). 2023 Jan 6;13:1066379. doi: 10.3389/fendo.2022.1066379. eCollection 2022. Benign thyroid nodules respond to a single administration of 0.3mg recombinant human thyrotropin with highly variable volume increase. Bountouris P(1), Markantes GK(1), Mamali I(1), Markou

The Effect of Low-Dose Ketamine in Treating Acute Asthma Attack; a Randomized Clinical Trial.

12. Emerg (Tehran). 2018;6(1):e21. Epub 2018 Apr 10. The Effect of Low-Dose Ketamine in Treating Acute Asthma Attack; a Randomized Clinical Trial. Esmailian M(1), Koushkian Esfahani M(1), Heydari F(1). Author information: (1)Emergency Medicine Research Center, Al-Zahra Research Institute, Isfaha

Effectiveness of low dose of rapamycin in preventing seizure-induced anxiety-like behaviour, cognitive impairment, and defects in neurogenesis in developing rats.

13. Int J Neurosci. 2020 Jan;130(1):9-18. doi: 10.1080/00207454.2018.1486827. Epub 2019 Oct 10. Effectiveness of low dose of rapamycin in preventing seizure-induced anxiety-like behaviour, cognitive impairment, and defects in neurogenesis in developing rats. Liu F(1)(2), Wu M(1)(2), Kai J(1)(2)

Dose-dependent effects of peroxisome proliferator-activated receptors β/δ agonist on systemic inflammation after haemorrhagic shock.

14. Cytokine. 2018 Mar;103:127-132. doi: 10.1016/j.cyto.2017.09.021. Epub 2017 Sep 30. Dose-dependent effects of peroxisome proliferator-activated receptors β/δ agonist on systemic inflammation after haemorrhagic shock. Yin L(1), Busch D(2), Qiao Z(3), van Griensven M(4), Teuben M(5), Hildebrand

Cannabinoids prevent the differential long-term effects of exposure to severe stress on hippocampal- and amygdala-dependent memory and plasticity.

15. Hippocampus. 2017 Oct;27(10):1093-1109. doi: 10.1002/hipo.22755. Epub 2017 Jul 14. Cannabinoids prevent the differential long-term effects of exposure to severe stress on hippocampal- and amygdala-dependent memory and plasticity. Shoshan N(1), Segev A(1), Abush H(1), Mizrachi Zer-Aviv T(1),

Methylphenidate has nonlinear dose effects on cued response inhibition in adults but not adolescents.

31. Brain Res. 2017 Jan 1;1654(Pt B):171-176. doi: 10.1016/j.brainres.2016.07.027. Epub 2016 Jul 16. Methylphenidate has nonlinear dose effects on cued response inhibition in adults but not adolescents. Simon NW(1), Moghaddam B(2). Author information: (1)University of Pittsburgh, Department of

Thyroxine administration prevents matrilineal intergenerational consequences of in utero ethanol exposure in rats.

8. Horm Behav. 2016 Jun;82:1-10. doi: 10.1016/j.yhbeh.2016.04.002. Epub 2016 Apr 16. Thyroxine administration prevents matrilineal intergenerational consequences of in utero ethanol exposure in rats. Tunc-Ozcan E(1), Harper KM(1), Graf EN(1), Redei EE(2). Author information: (1)The Asher Center

Low Dose, Low Cost Estradiol Pellets Can Support MCF-7 Tumour Growth in Nude Mice without Bladder Symptoms.

4. J Cancer. 2015 Oct 29;6(12):1331-6. doi: 10.7150/jca.10890. eCollection 2015. Low Dose, Low Cost Estradiol Pellets Can Support MCF-7 Tumour Growth in Nude Mice without Bladder Symptoms. Dall G(1), Vieusseux J(2), Unsworth A(2), Anderson R(3), Britt K(3). Author information: (1)1. Prostate Can

Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats.

33. Toxicol Appl Pharmacol. 2015 Aug 1;286(3):224-33. doi: 10.1016/j.taap.2015.05.004. Epub 2015 May 14. Osilodrostat (LCI699), a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats. Li L(1), Vash