락토바실러스 크리스파투스

Impact of oral administration of four Lactobacillus strains on Nugent score - systematic review and meta-analysis.

1. Benef Microbes. 2019 May 28;10(5):483-496. doi: 10.3920/BM2018.0129. Epub 2019 Apr 23. Impact of oral administration of four Lactobacillus strains on Nugent score - systematic review and meta-analysis. de Vrese M(1), Laue C(2), Papazova E(2), Petricevic L(3), Schrezenmeir J(2)(4). Author inf

Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial.

2. Cell Host Microbe. 2026 Apr 8;34(4):734-750.e10. doi: 10.1016/j.chom.2026.03.003. Epub 2026 Mar 27. Vaginal microbiota impacts of a Lactobacillus crispatus live biotherapeutic and predictors of colonization in randomized controlled trial. Bloom SM(1), Symul L(2), Elsherbini J(3), Xu J(3), Hus

VIBRANT: A phase 1 randomized trial of multi-strain vaginal L. crispatus live biotherapeutic products in people with bacterial vaginosis.

3. Cell Host Microbe. 2026 Apr 8;34(4):751-760.e5. doi: 10.1016/j.chom.2026.02.016. Epub 2026 Mar 18. VIBRANT: A phase 1 randomized trial of multi-strain vaginal L. crispatus live biotherapeutic products in people with bacterial vaginosis. Potloane D(1), Symul L(2), Ngcapu S(3), Lewis L(1), Fran

Efficacy and Safety of CO(2) Laser Therapy Combined with Collagen Cream in Managing Vulvo-Vaginal Atrophy: A Randomized, Controlled Study on Symptom Relief and Microbiome Modulation.

4. Medicina (Kaunas). 2026 Feb 3;62(2):314. doi: 10.3390/medicina62020314. Efficacy and Safety of CO(2) Laser Therapy Combined with Collagen Cream in Managing Vulvo-Vaginal Atrophy: A Randomized, Controlled Study on Symptom Relief and Microbiome Modulation. Filippini M(1), Sozzi J(1), de Góis Sp

Vaginal chlorhexidine gluconate versus fluconazole for recurrent vulvovaginal candidiasis: A randomized noninferiority trial.

5. PLoS One. 2026 Jan 20;21(1):e0340862. doi: 10.1371/journal.pone.0340862. eCollection 2026. Vaginal chlorhexidine gluconate versus fluconazole for recurrent vulvovaginal candidiasis: A randomized noninferiority trial. Alvendal C(1), Hasselrot T(2), Balduck M(2), Edfeldt G(3), Schuppe-Koistinen

Impact of a multi-strain L. crispatus-based vaginal synbiotic on the vaginal microbiome: a randomized placebo-controlled trial.

6. NPJ Biofilms Microbiomes. 2025 Aug 9;11(1):158. doi: 10.1038/s41522-025-00788-6. Impact of a multi-strain L. crispatus-based vaginal synbiotic on the vaginal microbiome: a randomized placebo-controlled trial. Ravel J(1), Simmons S(2), Jaswa EG(3), Gottfried S(4), Greene M(5), Kellogg-Spadt S(

Lactobacillus gasseri CECT 30648 shows probiotic characteristics and colonizes the vagina of healthy women after oral administration.

7. Microbiol Spectr. 2025 Sep 2;13(9):e0021125. doi: 10.1128/spectrum.00211-25. Epub 2025 Aug 7. Lactobacillus gasseri CECT 30648 shows probiotic characteristics and colonizes the vagina of healthy women after oral administration. Perez M(#)(1), Armengol E(#)(1)(2), Del Casale A(3), Campedelli I

Efficacy of clindamycin and LACTIN-V for in vitro fertilization patients with vaginal dysbiosis: a randomised double-blind, placebo-controlled multicentre trial.

8. Nat Commun. 2025 Jun 4;16(1):5166. doi: 10.1038/s41467-025-60205-6. Efficacy of clindamycin and LACTIN-V for in vitro fertilization patients with vaginal dysbiosis: a randomised double-blind, placebo-controlled multicentre trial. Haahr T(1)(2), Freiesleben NC(3)(4), Jensen MB(5), Elbaek HO(5)

Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a phase 2, randomised, placebo-controlled trial.

9. Lancet Microbe. 2025 Jun;6(6):101037. doi: 10.1016/j.lanmic.2024.101037. Epub 2025 Apr 4. Effect of the vaginal live biotherapeutic LACTIN-V (Lactobacillus crispatus CTV-05) on vaginal microbiota and genital tract inflammation among women at high risk of HIV acquisition in South Africa: a pha

Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parallel-group study.

10. Nutr Res. 2025 Feb;134:99-112. doi: 10.1016/j.nutres.2024.12.004. Epub 2024 Dec 26. Supplementation with heat-sterilized Lactobacillus crispatus strain KT-11 stimulates the T cell-related immune function of healthy Japanese adults: A pilot randomized, placebo-controlled, double-blind, parall

Vaginal microbiota stability over 18 months in young student women in France.

11. Eur J Clin Microbiol Infect Dis. 2024 Dec;43(12):2277-2292. doi: 10.1007/s10096-024-04943-3. Epub 2024 Sep 20. Vaginal microbiota stability over 18 months in young student women in France. Tamarelle J(1)(2), Thiébaut ACM(3), de Barbeyrac B(4), Bébéar C(4)(5), Bourret A(6)(7), Fauconnier A(8)

Synergistic antibacterial mechanism of the Lactobacillus crispatus surface layer protein and nisin on Staphylococcus saprophyticus.

12. Sci Rep. 2017 Mar 21;7(1):265. doi: 10.1038/s41598-017-00303-8. Synergistic antibacterial mechanism of the Lactobacillus crispatus surface layer protein and nisin on Staphylococcus saprophyticus. Sun Z(1), Li P(1), Liu F(2), Bian H(1), Wang D(3)(4), Wang X(1), Zou Y(1), Sun C(1), Xu W(1)(5).

Protease-Sensitive Inhibitory Activity of Cell-free Supernatant of Lactobacillus crispatus 156 Synergizes with Ciprofloxacin, Moxifloxacin and Streptomycin Against Pseudomonas aeruginosa: An In Vitro Study.

13. Probiotics Antimicrob Proteins. 2015 Jun;7(2):172-80. doi: 10.1007/s12602-015-9188-4. Protease-Sensitive Inhibitory Activity of Cell-free Supernatant of Lactobacillus crispatus 156 Synergizes with Ciprofloxacin, Moxifloxacin and Streptomycin Against Pseudomonas aeruginosa: An In Vitro Study.

Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment.

14. BMC Microbiol. 2025 Jan 28;25(1):52. doi: 10.1186/s12866-025-03767-1. Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment. Zhang Z(1), Zong X(1), Liu Z(2), Dong X(3), Bai H(4), Fan L(1), Li T(1). Author information

Microbiota composition of the female reproductive tract and miscarriage: a systematic review and meta-analysis.

15. NPJ Biofilms Microbiomes. 2026 Jan 8;12(1):78. doi: 10.1038/s41522-025-00901-9. Microbiota composition of the female reproductive tract and miscarriage: a systematic review and meta-analysis. Black N(1)(2), Henderson I(3), Quenby S(4)(5), Odendaal J(#)(4)(5), MacIntyre DA(#)(6)(7)(8)(9). Au

Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies.

24. Int J Mol Sci. 2025 Apr 30;26(9):4258. doi: 10.3390/ijms26094258. Association Between Vaginal Microbiota and Cervical Dysplasia Due to Persistent Human Papillomavirus Infection: A Systematic Review of Evidence from Shotgun Metagenomic Sequencing Studies. Žukienė G(1), Narutytė R(2), Rudaitis

The Vaginal Microbiota, Human Papillomavirus Infection, and Cervical Carcinogenesis: A Systematic Review in the Latina Population.

21. J Epidemiol Glob Health. 2024 Jun;14(2):480-497. doi: 10.1007/s44197-024-00201-z. Epub 2024 Feb 26. The Vaginal Microbiota, Human Papillomavirus Infection, and Cervical Carcinogenesis: A Systematic Review in the Latina Population. Mancilla V(1), Jimenez NR(2), Bishop NS(3), Flores M(4), Herb

Relationship of Lactobacillus Vaginal Microbiota Changes and the Risk of Preterm Birth: A Systematic Review and Meta-Analysis.

3. J Womens Health (Larchmt). 2024 Feb;33(2):228-238. doi: 10.1089/jwh.2023.0393. Epub 2023 Dec 8. Relationship of Lactobacillus Vaginal Microbiota Changes and the Risk of Preterm Birth: A Systematic Review and Meta-Analysis. Zhou Q(1), Yu Y(1), Zhou J(1), Liu J(1), Gao J(1). Author information

Can vaginal lactobacillus suppositories help reduce urinary tract infections?

6. Int Urogynecol J. 2023 Nov;34(11):2713-2718. doi: 10.1007/s00192-023-05568-4. Epub 2023 Jul 1. Can vaginal lactobacillus suppositories help reduce urinary tract infections? Shoureshi PS(1), Niino C(2), Eilber KS(3). Author information: (1)Department of Urology, Cedars-Sinai Medical Center, Lo

The vaginal microbiome and the risk of preterm birth: a systematic review and network meta-analysis.

6. Sci Rep. 2022 May 13;12(1):7926. doi: 10.1038/s41598-022-12007-9. The vaginal microbiome and the risk of preterm birth: a systematic review and network meta-analysis. Gudnadottir U(1), Debelius JW(2), Du J(2), Hugerth LW(2)(3), Danielsson H(2)(4), Schuppe-Koistinen I(2)(3), Fransson E(2)(5),

The Role of Genital Tract Microbiome in Fertility: A Systematic Review.

12. Int J Mol Sci. 2021 Dec 24;23(1):180. doi: 10.3390/ijms23010180. The Role of Genital Tract Microbiome in Fertility: A Systematic Review. Vitale SG(1), Ferrari F(2), Ciebiera M(3), Zgliczyńska M(3), Rapisarda AMC(1), Vecchio GM(4), Pino A(5)(6), Angelico G(7), Knafel A(3), Riemma G(8), De Fra

Associations of Cervicovaginal Lactobacilli With High-Risk Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia, and Cancer: A Systematic Review and Meta-Analysis.

14. J Infect Dis. 2019 Sep 13;220(8):1243-1254. doi: 10.1093/infdis/jiz325. Associations of Cervicovaginal Lactobacilli With High-Risk Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia, and Cancer: A Systematic Review and Meta-Analysis. Wang H(1), Ma Y(1), Li R(1), Chen X(1), Wa

The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta-analysis.

21. BJOG. 2020 Jan;127(2):171-180. doi: 10.1111/1471-0528.15854. Epub 2019 Jul 17. The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta-analysis. Norenhag J(1), Du J(2)(3), Olovsson M(1), Verstraelen H(4), Engstrand L(2)(3), Brusselaers N(2)(3