L-세린

Potential benefits of l-serine in children with GRIN2B loss-of-function variants: Randomized n-of-1 trials.

1. Mol Genet Metab. 2025 Dec;146(4):109268. doi: 10.1016/j.ymgme.2025.109268. Epub 2025 Oct 30. Potential benefits of l-serine in children with GRIN2B loss-of-function variants: Randomized n-of-1 trials. den Hollander B(1), Rothuizen-Lindenschot M(2), Le HL(3), Ramautar JR(4), Müller AR(1), Gee

Effect of a low-volume exercise intervention on the plasma lipidome in people with normal glucose, prediabetes or type 2 diabetes: a randomized controlled trial.

2. Am J Physiol Endocrinol Metab. 2025 Nov 1;329(5):E679-E691. doi: 10.1152/ajpendo.00171.2025. Epub 2025 Sep 29. Effect of a low-volume exercise intervention on the plasma lipidome in people with normal glucose, prediabetes or type 2 diabetes: a randomized controlled trial. Marian OC(1)(2), Mi

Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city.

3. Part Fibre Toxicol. 2025 Jul 8;22(1):18. doi: 10.1186/s12989-025-00638-5. Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city. Sun Y(1), Xiang Y(1), Chen Y(1), Xu D(1), Wang T(1), Zeng F(1), Bao Y(2), Zhao L(1), Li Y(1), Xia Q(1), Deng Y(1), Chen

Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems.

4. Nutrients. 2023 May 19;15(10):2377. doi: 10.3390/nu15102377. Analysis of the Effects of Known Sleep-Support Supplements in Relation to Life Habits, Sleep Conditions, and Sleep Problems. Imafuku F(1), Yamamoto K(1), Tanaka E(1), Aoki R(1), Nishino S(2). Author information: (1)Ezaki Glico Co.,

Mechanism of Guilu Erxian ointment based on targeted metabolomics in intervening in vitro fertilization and embryo transfer outcome in older patients with poor ovarian response of kidney-qi deficiency type.

5. Front Endocrinol (Lausanne). 2023 Jan 20;14:1045384. doi: 10.3389/fendo.2023.1045384. eCollection 2023. Mechanism of Guilu Erxian ointment based on targeted metabolomics in intervening in vitro fertilization and embryo transfer outcome in older patients with poor ovarian response of kidney-qi

Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.

6. Transl Neurodegener. 2023 Jan 26;12(1):4. doi: 10.1186/s40035-023-00336-2. Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial. Yulug B(#)(1), Altay O(#)(2), Li X(#)(2), Hanoglu L(3), Cankaya

Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study.

7. Cannabis Cannabinoid Res. 2024 Feb;9(1):188-198. doi: 10.1089/can.2022.0174. Epub 2022 Dec 9. Effects of Cannabidiol and Delta-9-Tetrahydrocannabinol on Plasma Endocannabinoid Levels in Healthy Volunteers: A Randomized Double-Blind Four-Arm Crossover Study. Chester LA(1), Englund A(2), Chesn

Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.

8. Adv Sci (Weinh). 2021 Sep;8(17):e2101222. doi: 10.1002/advs.202101222. Epub 2021 Jun 28. Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19. Altay O(1)(2), Arif M(1), Li X(1), Yang H(1), Aydın M(3), Alkurt G(4), Kim W(1), Akyol D(4), Zhang C(1)(5), Dinler-Doganay

Potential combinations of endocannabinoid/endocannabinoid-like compounds and antibiotics against methicillin-resistant Staphylococcus aureus.

9. PLoS One. 2020 Apr 15;15(4):e0231583. doi: 10.1371/journal.pone.0231583. eCollection 2020. Potential combinations of endocannabinoid/endocannabinoid-like compounds and antibiotics against methicillin-resistant Staphylococcus aureus. Feldman M(1), Smoum R(2), Mechoulam R(2), Steinberg D(1). A

Critical Synergistic Concentration of Lecithin Phospholipids Improves the Antimicrobial Activity of Eugenol against Escherichia coli.

10. Appl Environ Microbiol. 2017 Oct 17;83(21):e01583-17. doi: 10.1128/AEM.01583-17. Print 2017 Nov 1. Critical Synergistic Concentration of Lecithin Phospholipids Improves the Antimicrobial Activity of Eugenol against Escherichia coli. Zhang H(1), Dudley EG(1)(2), Harte F(3). Author informatio

l-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactive oxygen species production.

11. J Antimicrob Chemother. 2016 Aug;71(8):2192-9. doi: 10.1093/jac/dkw114. Epub 2016 Apr 26. l-Serine potentiates fluoroquinolone activity against Escherichia coli by enhancing endogenous reactive oxygen species production. Duan X(1), Huang X(1), Wang X(1), Yan S(1), Guo S(2), Abdalla AE(3), Hu

Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat.

12. Drug Metab Dispos. 2014 Jun;42(6):996-1007. doi: 10.1124/dmd.113.055194. Epub 2014 Apr 1. Aspirin and probenecid inhibit organic anion transporter 3-mediated renal uptake of cilostazol and probenecid induces metabolism of cilostazol in the rat. Wang C(1), Wang C, Liu Q, Meng Q, Cang J, Sun H

Improvement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemia.

13. PLoS One. 2013 Jun 25;8(6):e67044. doi: 10.1371/journal.pone.0067044. Print 2013. Improvement in regional CBF by L-serine contributes to its neuroprotective effect in rats after focal cerebral ischemia. Ren TJ(1), Qiang R, Jiang ZL, Wang GH, Sun L, Jiang R, Zhao GW, Han LY. Author informati

Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species.

14. J Neurosci Res. 2012 Jun;90(6):1218-29. doi: 10.1002/jnr.22832. Epub 2012 Feb 22. Cross-linking of serine racemase dimer by reactive oxygen species and reactive nitrogen species. Wang W(1), Barger SW. Author information: (1)Department of Geriatrics, University of Arkansas for Medical Scienc

Peptide cotransporter 1 in intestine and organic anion transporters in kidney are targets of interaction between JBP485 and lisinopril in rats.

15. Drug Metab Pharmacokinet. 2012;27(2):232-41. doi: 10.2133/dmpk.dmpk-11-rg-089. Epub 2011 Nov 29. Peptide cotransporter 1 in intestine and organic anion transporters in kidney are targets of interaction between JBP485 and lisinopril in rats. Guo X(1), Meng Q, Liu Q, Wang C, Mao Q, Sun H, Peng

Pharmacokinetic interaction between JBP485 and cephalexin in rats.

39. Drug Metab Dispos. 2010 Jun;38(6):930-8. doi: 10.1124/dmd.110.032060. Epub 2010 Mar 10. Pharmacokinetic interaction between JBP485 and cephalexin in rats. Zhang J(1), Wang C, Liu Q, Meng Q, Cang J, Sun H, Gao Y, Kaku T, Liu K. Author information: (1)Department of Clinical Pharmacology, Colle

N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels.

12. Br J Pharmacol. 2010 Jun;160(3):594-603. doi: 10.1111/j.1476-5381.2009.00622.x. Epub 2010 Feb 5. N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels. Parmar N(1), Ho WS. Author information: (1)Di

N-arachidonoyl L-serine, a putative endocannabinoid, alters the activation of N-type Ca2+ channels in sympathetic neurons.

29. J Neurophysiol. 2008 Aug;100(2):1147-51. doi: 10.1152/jn.01204.2007. Epub 2008 Jan 30. N-arachidonoyl L-serine, a putative endocannabinoid, alters the activation of N-type Ca2+ channels in sympathetic neurons. Guo J(1), Williams DJ, Ikeda SR. Author information: (1)Laboratory of Molecular P

Integrated proteomic and single-cell transcriptomic profiling elucidates immunomodulatory effects of L-serine in autism spectrum disorder.

45. Sci Rep. 2026 Mar 19. doi: 10.1038/s41598-026-43467-y. Online ahead of print. Integrated proteomic and single-cell transcriptomic profiling elucidates immunomodulatory effects of L-serine in autism spectrum disorder. Jang J(#)(1), Yeo S(#)(2), Kim JP(3), Baek S(1), Jung HJ(1), Hwang SK(4)(5),

AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism.

37. Biomedicines. 2023 Dec 12;11(12):3283. doi: 10.3390/biomedicines11123283. AST-001 Improves Social Deficits and Restores Dopamine Neuron Activity in a Mouse Model of Autism. Um KB(1), Kwak S(1), Cheon SH(1), Kim J(1), Hwang SK(1)(2). Author information: (1)Astrogen Inc., 440, Hyeoksin-daero,

Targeted Therapies for Hereditary Peripheral Neuropathies: Systematic Review and Steps Towards a 'treatabolome'.

27. J Neuromuscul Dis. 2021;8(3):383-400. doi: 10.3233/JND-200546. Targeted Therapies for Hereditary Peripheral Neuropathies: Systematic Review and Steps Towards a 'treatabolome'. Jennings MJ(1), Lochmüller A(2), Atalaia A(3), Horvath R(1). Author information: (1)Department of Clinical Neuroscie