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Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates.

1. Cochrane Database Syst Rev. 2006 Oct 18;2006(4):CD004869. doi: 10.1002/14651858.CD004869.pub2. Cysteine, cystine or N-acetylcysteine supplementation in parenterally fed neonates. Soghier LM(1), Brion LP. Author information: (1)Albert Einstein College of Medicine, Children's Hospital at Monte

N-Acetylcysteine is associated with changes in functional connectivity in patients with Parkinson's disease.

2. Parkinsonism Relat Disord. 2026 Mar;144:108216. doi: 10.1016/j.parkreldis.2026.108216. Epub 2026 Jan 27. N-Acetylcysteine is associated with changes in functional connectivity in patients with Parkinson's disease. Monti DA(1), Zabrecky G(1), Kremens D(2), Liang TW(2), Wintering NA(1), Vedaei

Efficacy and safety of the immunomodulator spleen aminopeptide combined with bismuth in the treatment of Helicobacter pylori infection: A randomized controlled trial.

3. Medicine (Baltimore). 2025 Oct 17;104(42):e44911. doi: 10.1097/MD.0000000000044911. Efficacy and safety of the immunomodulator spleen aminopeptide combined with bismuth in the treatment of Helicobacter pylori infection: A randomized controlled trial. Zhong W(1), Yang Y(2), Wang K(1), Luo LX(

A prospective randomized controlled trial of antioxidants in human IVF and embryo culture media.

4. Hum Reprod. 2025 Nov 1;40(11):2088-2100. doi: 10.1093/humrep/deaf183. A prospective randomized controlled trial of antioxidants in human IVF and embryo culture media. Kelley RL(1), Lee YSL(1), Agresta F(1), Pehrsson NG(2), Stevens JM(1), Huang A(1), Sgroi J(1), Rozen G(1)(3), Polyakov A(1)(4)

Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city.

5. Part Fibre Toxicol. 2025 Jul 8;22(1):18. doi: 10.1186/s12989-025-00638-5. Impacts of subway air particles on healthy adults: a randomized controlled trial in a Chinese city. Sun Y(1), Xiang Y(1), Chen Y(1), Xu D(1), Wang T(1), Zeng F(1), Bao Y(2), Zhao L(1), Li Y(1), Xia Q(1), Deng Y(1), Chen

Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators.

6. Free Radic Biol Med. 2023 Aug 1;204:347-358. doi: 10.1016/j.freeradbiomed.2023.05.013. Epub 2023 May 26. Longitudinal metabolomics analysis reveals the acute effect of cysteine and NAC included in the combined metabolic activators. Yang H(1), Li X(2), Jin H(3), Turkez H(4), Ozturk G(5), Dogan

Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation.

7. Am J Hematol. 2023 Jun;98(6):881-889. doi: 10.1002/ajh.26903. Epub 2023 Mar 23. Conditioning therapy with N-acetyl-L-cysteine, decitabine and modified BUCY regimen for myeloid malignancies patients prior to allogeneic hematopoietic stem cell transplantation. Tang Y(1)(2)(3), Zhang Z(1)(2)(3),

Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.

8. Transl Neurodegener. 2023 Jan 26;12(1):4. doi: 10.1186/s40035-023-00336-2. Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial. Yulug B(#)(1), Altay O(#)(2), Li X(#)(2), Hanoglu L(3), Cankaya

Use of N-acetylcysteine as treatment adjuvant regulates immune response in visceral leishmaniasis: Pilot clinical trial and in vitro experiments.

9. Front Cell Infect Microbiol. 2022 Nov 24;12:1045668. doi: 10.3389/fcimb.2022.1045668. eCollection 2022. Use of N-acetylcysteine as treatment adjuvant regulates immune response in visceral leishmaniasis: Pilot clinical trial and in vitro experiments. Magalhães LS(1)(2)(3), Melo EV(4), Damascen

Metabolomics strategy comprehensively unveils the effect of catechins intervention on the biomarkers of exposure to acrylamide and biomarkers of cardiometabolic risk.

10. Environ Int. 2022 Nov;169:107517. doi: 10.1016/j.envint.2022.107517. Epub 2022 Sep 12. Metabolomics strategy comprehensively unveils the effect of catechins intervention on the biomarkers of exposure to acrylamide and biomarkers of cardiometabolic risk. Wan X(1), Jia W(1), Wang Q(2), Chen X

Pilot Randomized Trial of a Three Times Weekly Heparin Flushing Intervention in Children, Adolescents, and Young Adults With Cancer With Tunneled Central Venous Catheters.

11. J Pediatr Hematol Oncol Nurs. 2023 Jan-Feb;40(1):24-33. doi: 10.1177/27527530221090479. Epub 2022 May 25. Pilot Randomized Trial of a Three Times Weekly Heparin Flushing Intervention in Children, Adolescents, and Young Adults With Cancer With Tunneled Central Venous Catheters. Adlard K(1)(2

Quercetin Enhances Topotecan Cytotoxicity in Retinoblastoma Cells Through ROS-Associated Stress and Apoptotic Signaling.

12. Biomolecules. 2026 Apr 17;16(4):597. doi: 10.3390/biom16040597. Quercetin Enhances Topotecan Cytotoxicity in Retinoblastoma Cells Through ROS-Associated Stress and Apoptotic Signaling. Maçin A(1), Duman E(2), Özdemir İ(3), Tuncer MC(4). Author information: (1)Department of Ophthalmology, Diy

Targeting the cysteine desulfhydrase-derived H(2)S: A phytochemical gallic acid as a synergistic agent against S. Typhimurium infection.

13. Microbiol Res. 2026 Jun;307:128482. doi: 10.1016/j.micres.2026.128482. Epub 2026 Feb 23. Targeting the cysteine desulfhydrase-derived H(2)S: A phytochemical gallic acid as a synergistic agent against S. Typhimurium infection. Lv H(1), Li S(1), Zhang H(1), Qiu J(1), Deng X(1), Ma H(2), Kong L

Synergistic effects of H(2)O(2), melatonin, and L-cysteine on biochemical traits and alkaloid accumulation in Catharanthus roseus L. "Ocellatus" in vitro plants.

14. BMC Plant Biol. 2026 Jan 28;26(1):361. doi: 10.1186/s12870-026-08230-5. Synergistic effects of H(2)O(2), melatonin, and L-cysteine on biochemical traits and alkaloid accumulation in Catharanthus roseus L. "Ocellatus" in vitro plants. Jafarpour E(1), Sanikhani M(2), Kheiry A(1), Razavi F(1).

Doxycycline Enhances Anticancer Activity of Zoledronic Acid via Inducing ROS and Autophagy in Osteosarcoma Cell Lines.

15. Int J Med Sci. 2025 May 9;22(11):2560-2569. doi: 10.7150/ijms.108086. eCollection 2025. Doxycycline Enhances Anticancer Activity of Zoledronic Acid via Inducing ROS and Autophagy in Osteosarcoma Cell Lines. Li YA(1)(2)(3)(4), Chen HY(5), Hsu CS(6), Tseng SC(4)(7), Hwang E(7)(8)(9)(10), Hsie

Enhanced tumor suppressive effect of a new HDAC inhibitor in bladder cancer in vitro and in vivo.

19. Biomed Pharmacother. 2025 Jun;187:118108. doi: 10.1016/j.biopha.2025.118108. Epub 2025 Apr 28. Enhanced tumor suppressive effect of a new HDAC inhibitor in bladder cancer in vitro and in vivo. Shen CH(1), Wu JY(2), Wang SC(3), Liu HT(2), Wu PX(2), Chan KW(4), Huang SW(4), Lee MY(5), Liu YW(

The cystathionine-γ-lyase inhibitor DL-propargylglycine augments the ability of L-cysteine ethyl ester to overcome the adverse effects of morphine on breathing.

30. Am J Physiol Lung Cell Mol Physiol. 2025 Jun 1;328(6):L809-L825. doi: 10.1152/ajplung.00003.2025. Epub 2025 Mar 18. The cystathionine-γ-lyase inhibitor DL-propargylglycine augments the ability of L-cysteine ethyl ester to overcome the adverse effects of morphine on breathing. Getsy PM(1), Co

NSC-3852 synergistically enhances the cytotoxicity of olaparib in oral squamous cell carcinoma.

34. Biochem Biophys Res Commun. 2025 Jan;744:151166. doi: 10.1016/j.bbrc.2024.151166. Epub 2024 Dec 11. NSC-3852 synergistically enhances the cytotoxicity of olaparib in oral squamous cell carcinoma. Sasaki Y(1), Inouchi T(2), Kise C(3), Nakatsuka R(4), Inoue A(5), Masutani M(6), Nozaki T(7).

Nimotuzumab and irinotecan synergistically induce ROS-mediated apoptosis by endoplasmic reticulum stress and mitochondrial-mediated pathway in cervical cancer.

9. Biotechnol Appl Biochem. 2025 Jun;72(3):730-742. doi: 10.1002/bab.2693. Epub 2024 Dec 3. Nimotuzumab and irinotecan synergistically induce ROS-mediated apoptosis by endoplasmic reticulum stress and mitochondrial-mediated pathway in cervical cancer. Teng F(1)(2), Zhao L(2). Author informatio

Phenylephrine Enhances the Mitogenic Effect of S-Allyl-L-cysteine on Primary Cultured Hepatocytes through Protein Kinase C-Induced B-Raf Phosphorylation.

1. Biol Pharm Bull. 2024;47(9):1565-1574. doi: 10.1248/bpb.b24-00157. Phenylephrine Enhances the Mitogenic Effect of S-Allyl-L-cysteine on Primary Cultured Hepatocytes through Protein Kinase C-Induced B-Raf Phosphorylation. Moteki H(1), Ogihara M(1), Kimura M(1). Author information: (1)Departmen

Inhibition of Autophagy Promotes Hemistepsin A-Induced Apoptosis via Reactive Oxygen Species-Mediated AMPK-Dependent Signaling in Human Prostate Cancer Cells.

1. Biomolecules. 2021 Dec 1;11(12):1806. doi: 10.3390/biom11121806. Inhibition of Autophagy Promotes Hemistepsin A-Induced Apoptosis via Reactive Oxygen Species-Mediated AMPK-Dependent Signaling in Human Prostate Cancer Cells. Kim KY(1), Yun UJ(2), Yeom SH(2)(3), Kim SC(3), Lee HJ(4), Ahn SC(5),

The efficacy and tolerability of pharmacologically active interventions for alcohol-induced hangover symptomatology: a systematic review of the evidence from randomised placebo-controlled trials.

9. Addiction. 2022 Aug;117(8):2157-2167. doi: 10.1111/add.15786. Epub 2022 Jan 24. The efficacy and tolerability of pharmacologically active interventions for alcohol-induced hangover symptomatology: a systematic review of the evidence from randomised placebo-controlled trials. Roberts E(1)(2)(3

Removal of acetaldehyde from saliva by a slow-release buccal tablet of L-cysteine.

31. Int J Cancer. 2002 Jan 20;97(3):361-4. doi: 10.1002/ijc.1620. Removal of acetaldehyde from saliva by a slow-release buccal tablet of L-cysteine. Salaspuro V(1), Hietala J, Kaihovaara P, Pihlajarinne L, Marvola M, Salaspuro M. Author information: (1)Research Unit of Substance Abuse Medicine,

Antibiofilm Effects of Novel Compounds in Otitis Media Treatment: Systematic Review.

32. Int J Mol Sci. 2024 Nov 29;25(23):12841. doi: 10.3390/ijms252312841. Antibiofilm Effects of Novel Compounds in Otitis Media Treatment: Systematic Review. Jotic A(1)(2), Savic Vujovic K(3), Cirkovic A(4), Božić DD(5), Brkic S(6), Subotic N(2), Bukurov B(1)(2), Korugic A(1)(2), Cirkovic I(7).

A systematic review: on the mercaptoacid metabolites of acrylamide, N-acetyl-S-(2-carbamoylethyl)-L-cysteine.

14. Environ Sci Pollut Res Int. 2023 Aug;30(38):88350-88365. doi: 10.1007/s11356-023-28714-3. Epub 2023 Jul 17. A systematic review: on the mercaptoacid metabolites of acrylamide, N-acetyl-S-(2-carbamoylethyl)-L-cysteine. Zhao FF(1), Wang XL(1), Lei YT(1), Li HQ(1), Li ZM(1), Hao XX(1), Ma WW(2)

Efficacy of management for obstruction caused by precipitated medication or lipids in central venous access devices: A systematic review and meta-analysis.

11. J Vasc Access. 2019 Nov;20(6):583-591. doi: 10.1177/1129729819836846. Epub 2019 Mar 28. Efficacy of management for obstruction caused by precipitated medication or lipids in central venous access devices: A systematic review and meta-analysis. Zheng LY(1), Xue H(2), Yuan H(1), Liu SX(1), Zha

Commercial products to preserve specimens for tuberculosis diagnosis: a systematic review.

3. Int J Tuberc Lung Dis. 2018 Jul 1;22(7):741-753. doi: 10.5588/ijtld.17.0816. Commercial products to preserve specimens for tuberculosis diagnosis: a systematic review. Reeve BWP(1), McFall SM(2), Song R(3), Warren R(1), Steingart KR(4), Theron G(1). Author information: (1)NRF/DST Centre of E

Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis.

10. Oral Oncol. 2015 Sep;51(9):805-18. doi: 10.1016/j.oraloncology.2015.06.010. Epub 2015 Jul 10. Diagnostic capability of salivary biomarkers in the assessment of head and neck cancer: A systematic review and meta-analysis. Guerra EN(1), Acevedo AC(2), Leite AF(2), Gozal D(3), Chardin H(4), De

Pre-medication to improve esophagogastroduodenoscopic visibility: a meta-analysis and systemic review.

47. Hepatogastroenterology. 2014 Sep;61(134):1642-8. Pre-medication to improve esophagogastroduodenoscopic visibility: a meta-analysis and systemic review. Chen HW, Hsu HC, Hsieh TY, Yeh MK, Chang WK. BACKGROUND/AIMS: The use of pre-medication to improve visibility in gastrointestinal endoscopy

Dietary supplements and prostate cancer: a systematic review of double-blind, placebo-controlled randomised clinical trials.

17. Maturitas. 2013 Jun;75(2):125-30. doi: 10.1016/j.maturitas.2013.03.006. Epub 2013 Apr 6. Dietary supplements and prostate cancer: a systematic review of double-blind, placebo-controlled randomised clinical trials. Posadzki P(1), Lee MS, Onakpoya I, Lee HW, Ko BS, Ernst E. Author information