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Effect of kava (Piper methysticum) on peripheral gene expression among individuals with generalized anxiety disorder: A post hoc analysis of a randomized controlled trial.

1. Phytother Res. 2023 Dec;37(12):5897-5903. doi: 10.1002/ptr.7999. Epub 2023 Sep 28. Effect of kava (Piper methysticum) on peripheral gene expression among individuals with generalized anxiety disorder: A post hoc analysis of a randomized controlled trial. Cribb L(1), Sarris J(2)(3), Savage KM

Kava (Piper methysticum) in the United States: the quiet rise of a substance with often subtle effects.

2. Am J Drug Alcohol Abuse. 2023 Jan 2;49(1):85-96. doi: 10.1080/00952990.2022.2140292. Epub 2022 Nov 21. Kava (Piper methysticum) in the United States: the quiet rise of a substance with often subtle effects. Pont-Fernandez S(1), Kheyfets M(1), Rogers JM(1), Smith KE(1), Epstein DH(1). Author

Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism.

3. PLoS One. 2016 Jun 22;11(6):e0157700. doi: 10.1371/journal.pone.0157700. eCollection 2016. Kavain, the Major Constituent of the Anxiolytic Kava Extract, Potentiates GABAA Receptors: Functional Characteristics and Molecular Mechanism. Chua HC(1), Christensen ET(1)(2), Hoestgaard-Jensen K(2), H

Clinically Relevant Pharmacokinetic Herb-drug Interactions in Antiretroviral Therapy.

4. Curr Drug Metab. 2015;17(1):52-64. doi: 10.2174/1389200216666151103115053. Clinically Relevant Pharmacokinetic Herb-drug Interactions in Antiretroviral Therapy. Fasinu PS(1), Gurley BJ, Walker LA. Author information: (1)National Center for Natural products Research, School of Pharmacy, Univer

Tradition and toxicity: evidential cultures in the kava safety debate.

5. Soc Stud Sci. 2011 Jun;41(3):361-84. doi: 10.1177/0306312710395341. Tradition and toxicity: evidential cultures in the kava safety debate. Baker JD(1). Author information: (1)Department of Anthropology, University of Hawai'i at Mānoa, Honolulu, HI 96822, USA. bakerjon@hawaii.edu This paper e

Kava (Piper methysticum).

6. J Soc Integr Oncol. 2009 Fall;7(4):170-2. Kava (Piper methysticum). [No authors listed] PMID: 19883532 [Indexed for MEDLINE]

Interactions between herbal medicines and prescribed drugs: an updated systematic review.

7. Drugs. 2009;69(13):1777-98. doi: 10.2165/11317010-000000000-00000. Interactions between herbal medicines and prescribed drugs: an updated systematic review. Izzo AA(1), Ernst E. Author information: (1)Department of Experimental Pharmacology, University of Naples Federico II, via D Montesano

Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.

8. Mol Nutr Food Res. 2008 Jul;52(7):755-63. doi: 10.1002/mnfr.200600300. Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea. Gurley BJ(1), Swain A, Hubbard MA, Williams DK, Barone

Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo.

9. Clin Pharmacol Ther. 2008 Jan;83(1):61-9. doi: 10.1038/sj.clpt.6100222. Epub 2007 May 9. Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivo. Gurley BJ(1), Swain A, Hubbard MA, Hartsfield F, Thaden J, Williams DK

Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans.

10. Drug Metab Dispos. 2007 Feb;35(2):240-5. doi: 10.1124/dmd.106.012708. Epub 2006 Nov 1. Effect of goldenseal (Hydrastis canadensis) and kava kava (Piper methysticum) supplementation on digoxin pharmacokinetics in humans. Gurley BJ(1), Swain A, Barone GW, Williams DK, Breen P, Yates CR, Stuart

Kavalactones fail to inhibit alcohol dehydrogenase in vitro.

11. Phytomedicine. 2006 Feb;13(3):192-5. doi: 10.1016/j.phymed.2004.07.005. Epub 2005 Jun 28. Kavalactones fail to inhibit alcohol dehydrogenase in vitro. Anke J(1), Fu S, Ramzan I. Author information: (1)Faculty of Pharmacy, University of Sydney, NSW, Australia. In recent years, Kava kava (Pip

The protective effects of Kava (Piper Methysticum) constituents in cancers: A systematic review.

12. J Oral Pathol Med. 2019 Aug;48(7):510-529. doi: 10.1111/jop.12900. Epub 2019 Jul 8. The protective effects of Kava (Piper Methysticum) constituents in cancers: A systematic review. Celentano A(1), Tran A(1), Testa C(1), Thayanantha K(1), Tan-Orders W(1), Tan S(1), Syamal M(1), McCullough MJ

Kava for Generalized Anxiety Disorder: A Review of Current Evidence.

13. J Altern Complement Med. 2018 Aug;24(8):770-780. doi: 10.1089/acm.2018.0001. Epub 2018 Apr 11. Kava for Generalized Anxiety Disorder: A Review of Current Evidence. Ooi SL(1), Henderson P(2), Pak SC(2). Author information: (1)1 Centre for Complementary and Alternative Medicine , Singapore, Si

Complementary and Alternative Medicine Treatments for Generalized Anxiety Disorder: Systematic Review and Meta-analysis of Randomized Controlled Trials.

14. Adv Ther. 2018 Mar;35(3):261-288. doi: 10.1007/s12325-018-0680-6. Epub 2018 Mar 5. Complementary and Alternative Medicine Treatments for Generalized Anxiety Disorder: Systematic Review and Meta-analysis of Randomized Controlled Trials. Barić H(1), Đorđević V(2), Cerovečki I(3), Trkulja V(4).

Neurocognitive effects of kava (Piper methysticum): a systematic review.

15. Hum Psychopharmacol. 2011 Mar;26(2):102-11. doi: 10.1002/hup.1180. Epub 2011 Mar 16. Neurocognitive effects of kava (Piper methysticum): a systematic review. LaPorte E(1), Sarris J, Stough C, Scholey A. Author information: (1)Brain Sciences Institute, University of Technology, Melbourne, Vic

Kava and St. John's Wort: current evidence for use in mood and anxiety disorders.

27. J Altern Complement Med. 2009 Aug;15(8):827-36. doi: 10.1089/acm.2009.0066. Kava and St. John's Wort: current evidence for use in mood and anxiety disorders. Sarris J(1), Kavanagh DJ. Author information: (1)School of Medicine, The University of Queensland, Royal Brisbane and Women's Hospita

Safety review of kava (Piper methysticum) by the Natural Standard Research Collaboration.

44. Expert Opin Drug Saf. 2005 Jul;4(4):779-94. doi: 10.1517/14740338.4.4.779. Safety review of kava (Piper methysticum) by the Natural Standard Research Collaboration. Ulbricht C(1), Basch E, Boon H, Ernst E, Hammerness P, Sollars D, Tsourounis C, Woods J, Bent S. Author information: (1)Natura

A systematic review of the safety of kava extract in the treatment of anxiety.

50. Drug Saf. 2002;25(4):251-61. doi: 10.2165/00002018-200225040-00003. A systematic review of the safety of kava extract in the treatment of anxiety. Stevinson C(1), Huntley A, Ernst E. Author information: (1)Department of Complementary Medicine, University of Exeter, Exeter, United Kingdom. T

Interactions between herbal medicines and prescribed drugs: a systematic review.

49. Drugs. 2001;61(15):2163-75. doi: 10.2165/00003495-200161150-00002. Interactions between herbal medicines and prescribed drugs: a systematic review. Izzo AA(1), Ernst E. Author information: (1)Department of Experimental Pharmacology, University of Naples 'Federico II', Naples, Italy. Despite