히비스커스

Efficacy and safety of Hibiscus sabdariffa in cardiometabolic health: An overview of reviews and updated dose-response meta-analysis.

1. Complement Ther Med. 2025 May;89:103135. doi: 10.1016/j.ctim.2025.103135. Epub 2025 Jan 25. Efficacy and safety of Hibiscus sabdariffa in cardiometabolic health: An overview of reviews and updated dose-response meta-analysis. Norouzzadeh M(1), Hasan Rashedi M(1), Azizi MH(2), Teymoori F(3), M

Effect of Hibiscus sabdariffa (Roselle) supplementation in regulating blood lipids among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis.

2. Phytother Res. 2020 May;34(5):1083-1095. doi: 10.1002/ptr.6592. Epub 2019 Dec 12. Effect of Hibiscus sabdariffa (Roselle) supplementation in regulating blood lipids among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis. Zhang B(1), Yue R(1), Wang

Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials.

3. J Hypertens. 2015 Jun;33(6):1119-27. doi: 10.1097/HJH.0000000000000585. Effect of sour tea (Hibiscus sabdariffa L.) on arterial hypertension: a systematic review and meta-analysis of randomized controlled trials. Serban C(1), Sahebkar A, Ursoniu S, Andrica F, Banach M. Author information: (1)

Lactobacillus, vitamin C, cranberry and hibiscus versus placebo for prolonging the latency period of premature rupture of membranes: a double-blind randomized clinical trial.

4. Eur J Obstet Gynecol Reprod Biol. 2026 Feb 20;318:114938. doi: 10.1016/j.ejogrb.2026.114938. Epub 2026 Jan 3. Lactobacillus, vitamin C, cranberry and hibiscus versus placebo for prolonging the latency period of premature rupture of membranes: a double-blind randomized clinical trial. Portill

Standardized Hibiscus-Inulin Shot Lowers Lipid-Glucose Indices in Adults with Overweight and Obesity: 8-Week Randomized Trial.

5. Nutrients. 2025 Nov 14;17(22):3556. doi: 10.3390/nu17223556. Standardized Hibiscus-Inulin Shot Lowers Lipid-Glucose Indices in Adults with Overweight and Obesity: 8-Week Randomized Trial. Mendivil EJ(1), Rivera-Iñiguez I(2), Arellano-Gómez LP(3), Martínez-López E(4), Hernández-Guerrero C(1),

Anti-TNF Therapies Promote a Proximal-to-Distal Healing Pattern in Moderate-to-Severe Ulcerative Colitis.

6. Inflamm Bowel Dis. 2026 Jan 1;32(1):87-96. doi: 10.1093/ibd/izaf199. Anti-TNF Therapies Promote a Proximal-to-Distal Healing Pattern in Moderate-to-Severe Ulcerative Colitis. Wong ECL(1), Dulai PS(2), Marshall JK(1), Jairath V(3), Reinisch W(4), Narula N(1). Author information: (1)Division o

Hibiscus Collagen Alternative (VC-H1) as an Oral Skin Rejuvenating Agent: A 12-Week Pilot Study.

7. Int J Mol Sci. 2025 Jul 28;26(15):7291. doi: 10.3390/ijms26157291. Hibiscus Collagen Alternative (VC-H1) as an Oral Skin Rejuvenating Agent: A 12-Week Pilot Study. Baek Y(1), Nguyen NH(1)(2), Lee YI(1)(3), Jung MJ(4), Kim IA(4), Lee SJ(5), Kim HM(6), Lee JH(1)(3). Author information: (1)Depa

Efficacy of Hibiscus sabdariffa L. extract on metabolic parameters in participants with abdominal obesity and mild metabolic syndrome in Bangkok, Thailand: A double-blind, randomized, placebo-controlled trial.

8. Complement Ther Med. 2025 Aug;91:103185. doi: 10.1016/j.ctim.2025.103185. Epub 2025 May 5. Efficacy of Hibiscus sabdariffa L. extract on metabolic parameters in participants with abdominal obesity and mild metabolic syndrome in Bangkok, Thailand: A double-blind, randomized, placebo-controlled

Acute effects of Hibiscus sabdariffa on blood pressure and cognitive function.

9. Nutr Neurosci. 2025 Sep;28(9):1093-1103. doi: 10.1080/1028415X.2025.2462944. Epub 2025 Feb 26. Acute effects of Hibiscus sabdariffa on blood pressure and cognitive function. Ellis L(1)(2), Aragón-Rojas S(2), Dye L(2)(3), Boesch C(2). Author information: (1)School of Psychology, University of

Effect of dietary supplementation with Diuripres® on blood pressure, vascular health, and metabolic parameters in individuals with high-normal blood pressure or stage I hypertension: The CONDOR randomized clinical study.

10. Phytother Res. 2023 Oct;37(10):4851-4861. doi: 10.1002/ptr.7951. Epub 2023 Jul 14. Effect of dietary supplementation with Diuripres® on blood pressure, vascular health, and metabolic parameters in individuals with high-normal blood pressure or stage I hypertension: The CONDOR randomized clin

Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial.

11. Oxid Med Cell Longev. 2022 Sep 21;2022:4631983. doi: 10.1155/2022/4631983. eCollection 2022. Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomi

Improvement on blood pressure and skin using roselle drink: A clinical trial.

12. J Food Biochem. 2022 Oct;46(10):e14287. doi: 10.1111/jfbc.14287. Epub 2022 Jun 27. Improvement on blood pressure and skin using roselle drink: A clinical trial. Chiu HF(1), Liao YR(2), Shen YC(3), Han YC(4), Golovinskaia O(2), Venkatakrishnan K(2), Hung CC(5), Wang CK(2). Author information

Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials.

13. Lancet Gastroenterol Hepatol. 2022 Jan;7(1):17-27. doi: 10.1016/S2468-1253(21)00338-1. Epub 2021 Nov 17. Etrolizumab versus adalimumab or placebo as induction therapy for moderately to severely active ulcerative colitis (HIBISCUS): two phase 3 randomised, controlled trials. Rubin DT(1), Dot

Effect of Hibiscus sabdariffa and Zingiber officinale on pharmacokinetics and pharmacodynamics of amlodipine.

14. J Pharm Pharmacol. 2021 Aug 12;73(9):1151-1160. doi: 10.1093/jpp/rgaa062. Effect of Hibiscus sabdariffa and Zingiber officinale on pharmacokinetics and pharmacodynamics of amlodipine. Alam MA(1), Bin Jardan YA(1), Alzenaidy B(1), Raish M(1), Al-Mohizea AM(1), Ahad A(1), Al-Jenoobi FI(1). Au

Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats.

15. Xenobiotica. 2020 Jul;50(7):847-857. doi: 10.1080/00498254.2020.1729446. Epub 2020 Mar 5. Effect of Hibiscus sabdariffa and Zingiber officinale on the antihypertensive activity and pharmacokinetic of losartan in hypertensive rats. Ahad A(1), Raish M(1), Bin Jardan YA(1), Alam MA(1), Al-Mohiz

Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics.

10. BMC Complement Altern Med. 2019 May 6;19(1):98. doi: 10.1186/s12906-019-2505-9. Hibiscus flower extract selectively induces apoptosis in breast cancer cells and positively interacts with common chemotherapeutics. Nguyen C(1), Baskaran K(1), Pupulin A(1), Ruvinov I(1), Zaitoon O(1), Grewal S(

In vitro modulation of cytochrome P450 isozymes and pharmacokinetics of caffeine by extracts of Hibiscus sabdariffa Linn calyx.

17. J Basic Clin Physiol Pharmacol. 2019 Apr 5;30(3). doi: 10.1515/jbcpp-2018-0206. In vitro modulation of cytochrome P450 isozymes and pharmacokinetics of caffeine by extracts of Hibiscus sabdariffa Linn calyx. Showande JS(1), Igbinoba SI(2), Kajula M(3), Hokkanen J(3), Tolonen A(3), Adegbolagu

In vivo pharmacodynamic and pharmacokinetic interactions of Hibiscus sabdariffa calyces extracts with simvastatin.

1. J Clin Pharm Ther. 2017 Dec;42(6):695-703. doi: 10.1111/jcpt.12629. Epub 2017 Sep 18. In vivo pharmacodynamic and pharmacokinetic interactions of Hibiscus sabdariffa calyces extracts with simvastatin. Showande SJ(1), Adegbolagun OM(2), Igbinoba SI(3), Fakeye TO(1). Author information: (1)Dep

Herbal products containing Hibiscus sabdariffa L., Crataegus spp., and Panax spp.: Labeling and safety concerns.

17. Food Res Int. 2017 Oct;100(Pt 1):529-540. doi: 10.1016/j.foodres.2017.07.031. Epub 2017 Jul 19. Herbal products containing Hibiscus sabdariffa L., Crataegus spp., and Panax spp.: Labeling and safety concerns. Nunes MA(1), Rodrigues F(1), Alves RC(2), Oliveira MBPP(1). Author information: (1

Cutaneous Toxicity Induced by Hibiscus Tea in a Patient Treated with Erlotinib.

9. J Thorac Oncol. 2017 May;12(5):e47-e48. doi: 10.1016/j.jtho.2017.01.010. Cutaneous Toxicity Induced by Hibiscus Tea in a Patient Treated with Erlotinib. Jacquin-Porretaz C(1), Gérard B(2), Nardin C(1), Drobacheff-Thiebaut C(3), Blanc D(1), Jacoulet P(4), Westeel V(4), Aubin F(5). Author infor

Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B(12) deficiency with neurological symptoms.

45. Fundam Clin Pharmacol. 2016 Dec;30(6):568-576. doi: 10.1111/fcp.12220. Epub 2016 Sep 30. Hibiscus sabdariffa increases hydroxocobalamin oral bioavailability and clinical efficacy in vitamin B(12) deficiency with neurological symptoms. Souirti Z(1)(2), Loukili M(1), Soudy ID(3)(4), Rtibi K(3)

Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast cancer cell lines.

24. J Colloid Interface Sci. 2016 May 15;470:142-152. doi: 10.1016/j.jcis.2016.02.043. Epub 2016 Feb 18. Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast cancer cell lines. Nayak

In vitro synergistic effect of Hibiscus sabdariffa aqueous extract in combination with standard antibiotics against Helicobacter pylori clinical isolates.

18. Pharm Biol. 2016 Sep;54(9):1736-40. doi: 10.3109/13880209.2015.1126618. Epub 2016 Jan 5. In vitro synergistic effect of Hibiscus sabdariffa aqueous extract in combination with standard antibiotics against Helicobacter pylori clinical isolates. Hassan ST(1)(2), Berchová K(2), Majerová M(1),

Protocol for a randomized controlled trial evaluating the effect of Hibiscus syriacus L. flower extract on sleep quality.

36. Front Nutr. 2023 Apr 20;10:1169193. doi: 10.3389/fnut.2023.1169193. eCollection 2023. Protocol for a randomized controlled trial evaluating the effect of Hibiscus syriacus L. flower extract on sleep quality. Choi Y(1), Park YH(2), Yang C(1), Kim DH(2), Lee KW(2), Lee MY(3). Author informati

Pharmacological effects of aqueous-ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion.

44. Asian Pac J Trop Med. 2011 Nov;4(11):883-8. doi: 10.1016/S1995-7645(11)60213-7. Pharmacological effects of aqueous-ethanolic extract of Hibiscus rosasinensis on volume and acidity of stimulated gastric secretion. Mandade RJ(1), Sreenivas SA, Sakarkar DM, Choudhury A. Author information: (1)P

Revolutionising shift in advanced wound healing therapies: nanoengineered herbal gels.

37. Nat Prod Res. 2025 Dec;39(23):6900-6915. doi: 10.1080/14786419.2024.2436111. Epub 2024 Dec 3. Revolutionising shift in advanced wound healing therapies: nanoengineered herbal gels. Singh R(1)(2), Kumar J(1), Rajput SK(1), Bhardwaj R(1), Ranjan G(2). Author information: (1)Department of Phar

Clinical effects of Hibiscus sabdariffa Linn. on obesity treatment: A systematic review and meta-analysis of randomized controlled trials.

26. Complement Ther Med. 2024 Sep;84:103063. doi: 10.1016/j.ctim.2024.103063. Epub 2024 Jun 13. Clinical effects of Hibiscus sabdariffa Linn. on obesity treatment: A systematic review and meta-analysis of randomized controlled trials. Dilokthornsakul P(1), Rattanachaisit N(2), Thimkorn P(3), Pon

Medicinal plants with anti-colorectal cancer bioactive compounds: Potential game-changers in colorectal cancer management.

32. Biomed Pharmacother. 2022 Sep;153:113383. doi: 10.1016/j.biopha.2022.113383. Epub 2022 Jul 9. Medicinal plants with anti-colorectal cancer bioactive compounds: Potential game-changers in colorectal cancer management. Macharia JM(1), Mwangi RW(2), Rozmann N(3), Zsolt K(3), Varjas T(3), Uchech

A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers.

9. Nutr Rev. 2022 May 9;80(6):1723-1737. doi: 10.1093/nutrit/nuab104. A systematic review and meta-analysis of the effects of Hibiscus sabdariffa on blood pressure and cardiometabolic markers. Ellis LR(1), Zulfiqar S(2), Holmes M(2), Marshall L(2), Dye L(1), Boesch C(2). Author information: (1)S

Roselle for hypertension in adults.

15. Cochrane Database Syst Rev. 2021 Nov 27;11(11):CD007894. doi: 10.1002/14651858.CD007894.pub3. Roselle for hypertension in adults. Pattanittum P(1), Ngamjarus C(1), Buttramee F(2), Somboonporn C(3). Author information: (1)Department of Epidemiology and Biostatistics, Faculty of Public Health,