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The Effect of Aged Garlic Supplementation on Blood Pressure and Lipid Profile: A Dose-Response Grade-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials.

1. Phytother Res. 2025 Dec;39(12):5669-5694. doi: 10.1002/ptr.70032. Epub 2025 Jul 8. The Effect of Aged Garlic Supplementation on Blood Pressure and Lipid Profile: A Dose-Response Grade-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials. Bashiri S(1), TaghipourSheshde

Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

2. Nutr Rev. 2026 Jan 1;84(1):1-35. doi: 10.1093/nutrit/nuaf090. Effects of Garlic Supplementation on Cardiovascular Risk Factors in Adults: A Comprehensive Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. Behrouz V(1)(2), Zahroodi M(3), Clark CCT(4), Mir E(3), Atashi

Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials.

3. Prostaglandins Other Lipid Mediat. 2024 Dec;175:106914. doi: 10.1016/j.prostaglandins.2024.106914. Epub 2024 Oct 20. Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials. Saadh MJ(1), Kariem M(2), Shuk

Effects of garlic supplementation on components of metabolic syndrome: a systematic review, meta-analysis, and meta-regression of randomized controlled trials.

4. BMC Complement Med Ther. 2023 Jul 22;23(1):260. doi: 10.1186/s12906-023-04038-0. Effects of garlic supplementation on components of metabolic syndrome: a systematic review, meta-analysis, and meta-regression of randomized controlled trials. Fu Z(#)(1)(2), Lv J(#)(1), Gao X(#)(1)(2), Zheng H(1

Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses.

5. Br J Clin Pharmacol. 2017 Jan;83(1):163-171. doi: 10.1111/bcp.12902. Epub 2016 Mar 15. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses. Borghi C(1), Cicero AF(1). Author information: (1)Depar

Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review.

6. J Nutr. 2016 Feb;146(2):389S-396S. doi: 10.3945/jn.114.202192. Epub 2016 Jan 13. Garlic Lowers Blood Pressure in Hypertensive Individuals, Regulates Serum Cholesterol, and Stimulates Immunity: An Updated Meta-analysis and Review. Ried K(1). Author information: (1)National Institute of Integra

Effect of garlic on blood pressure: a meta-analysis.

7. J Clin Hypertens (Greenwich). 2015 Mar;17(3):223-31. doi: 10.1111/jch.12473. Epub 2015 Jan 5. Effect of garlic on blood pressure: a meta-analysis. Wang HP(1), Yang J, Qin LQ, Yang XJ. Author information: (1)Department of Cardiovascular, The First Affiliated Hospital of Soochow University, Su

Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial.

8. J Health Popul Nutr. 2025 Aug 6;44(1):282. doi: 10.1186/s41043-025-01025-8. Efficacy of garlic (Allium sativum) on metabolic syndrome components in women with polycystic ovary syndrome: randomized controlled trial. Hesari NG(1), Sadatmahalleh SJ(2), Mohebbi P(3), Nasiri M(4), Khosravi A(5). A

LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers.

9. Nutrients. 2024 Aug 22;16(16):2811. doi: 10.3390/nu16162811. LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers. Vezza T(1)(2), Guillamón E(3), García-García J(2)(4), Baños A(3), Mut-Salud N(3), García-López JD(3), Gómez-Fer

Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension.

10. Horm Mol Biol Clin Investig. 2024 Jul 15;45(4):139-147. doi: 10.1515/hmbci-2024-0019. eCollection 2024 Dec 1. Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk

Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.

11. Nutrients. 2023 Aug 23;15(17):3691. doi: 10.3390/nu15173691. Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial. Serrano JCE(1), Castro-Boqué E(2), García-Carrasco A

Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial.

12. Nutrients. 2022 Dec 8;14(24):5238. doi: 10.3390/nu14245238. Effects of Fermented Garlic Extract Containing Nitric Oxide Metabolites on Blood Flow in Healthy Participants: A Randomized Controlled Trial. Baik JS(1), Min JH(2), Ju SM(3), Ahn JH(4), Ko SH(2)(5), Chon HS(6), Kim MS(7), Shin YI(2)

Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial.

13. Eur J Nutr. 2022 Oct;61(7):3357-3366. doi: 10.1007/s00394-022-02895-y. Epub 2022 May 4. Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial. Leitão R(1), de Oli

Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.

14. Nutrients. 2022 Jan 18;14(3):405. doi: 10.3390/nu14030405. Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study. Valls RM(1), Companys J(2), Calderón-

Evaluating the effects of dark chocolate formulated with micro-encapsulated fermented garlic extract on cardio-metabolic indices in hypertensive patients: A crossover, triple-blind placebo-controlled randomized clinical trial.

15. Phytother Res. 2022 Apr;36(4):1785-1796. doi: 10.1002/ptr.7421. Epub 2022 Mar 9. Evaluating the effects of dark chocolate formulated with micro-encapsulated fermented garlic extract on cardio-metabolic indices in hypertensive patients: A crossover, triple-blind placebo-controlled randomized c

The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial.

36. Phytother Res. 2021 Nov;35(11):6335-6342. doi: 10.1002/ptr.7282. Epub 2021 Sep 8. The effect of garlic (Allium sativum) supplementation on the lipid parameters and blood pressure levels in women with polycystic ovary syndrome: A randomized controlled trial. Zadhoush R(1), Alavi-Naeini A(1),

Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial.

14. Phytother Res. 2021 Aug;35(8):4433-4441. doi: 10.1002/ptr.7146. Epub 2021 May 11. Effects of garlic powder supplementation on metabolic syndrome components, insulin resistance, fatty liver index, and appetite in subjects with metabolic syndrome: A randomized clinical trial. Sangouni AA(1)(2

Clinical herbal interactions with conventional drugs: from molecules to maladies.

24. Curr Med Chem. 2011;18(31):4836-50. doi: 10.2174/092986711797535317. Clinical herbal interactions with conventional drugs: from molecules to maladies. Chen XW(1), Serag ES, Sneed KB, Liang J, Chew H, Pan SY, Zhou SF. Author information: (1)Department of General Surgery, Shunde First People’s

Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril.

21. Phytomedicine. 2010 Nov;17(13):1016-26. doi: 10.1016/j.phymed.2010.07.012. Epub 2010 Aug 23. Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril. Asdaq SM(1), Inamdar MN. Author information: (1)Department of Pha

The potential for interaction of hydrochlorothiazide with garlic in rats.

34. Chem Biol Interact. 2009 Oct 30;181(3):472-9. doi: 10.1016/j.cbi.2009.07.022. Epub 2009 Aug 4. The potential for interaction of hydrochlorothiazide with garlic in rats. Asdaq SM(1), Inamdar MN. Author information: (1)Department of Pharmacology, Krupanidhi College of Pharmacy, Varthur Hobli,

Aged garlic extract may be safe for patients on warfarin therapy.

32. J Nutr. 2006 Mar;136(3 Suppl):793S-795S. doi: 10.1093/jn/136.3.793S. Aged garlic extract may be safe for patients on warfarin therapy. Macan H(1), Uykimpang R, Alconcel M, Takasu J, Razon R, Amagase H, Niihara Y. Author information: (1)Department of Medicine, Harbor-UCLA Medical Center, UCLA

What's cooking with garlic: is this complementary and alternative medicine for hypertension?

19. J Am Acad Nurse Pract. 2005 Sep;17(9):381-5. doi: 10.1111/j.1745-7599.2005.00065.x. What's cooking with garlic: is this complementary and alternative medicine for hypertension? Edwards QT(1), Colquist S, Maradiegue A. Author information: (1)Family Nurse Practitioner Program, Howard Universi

Health effects of garlic.

25. Am Fam Physician. 2005 Jul 1;72(1):103-6. Health effects of garlic. Tattelman E(1). Author information: (1)Department of Family and Social Medicine, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York 10467, USA. etattelm@montefiore.org Garlic has long been used medic

Herb-drug interactions: a literature review.

9. Drugs. 2005;65(9):1239-82. doi: 10.2165/00003495-200565090-00005. Herb-drug interactions: a literature review. Hu Z(1), Yang X, Ho PC, Chan SY, Heng PW, Chan E, Duan W, Koh HL, Zhou S. Author information: (1)Department of Pharmacy, Faculty of Science, National University of Singapore, Singapo

Trends in use of herbal and nutritional supplements in cardiovascular patients.

12. Clin Cardiol. 2004 Feb;27(2):87-90. doi: 10.1002/clc.4960270208. Trends in use of herbal and nutritional supplements in cardiovascular patients. Stys T(1), Stys A, Kelly P, Lawson W. Author information: (1)Division of Cardiology, State University of New York at Stony Brook, New York 11790, U

Use of alternative pharmacotherapy in management of cardiovascular diseases.

47. Am J Manag Care. 2002 Mar;8(3):270-85; quiz 286-8. Use of alternative pharmacotherapy in management of cardiovascular diseases. Chagan L(1), Ioselovich A, Asherova L, Cheng JW. Author information: (1)Shore Health System, Easton, MD, USA. OBJECTIVES: To review use of alternative pharmacothera

Interactions between herbal medicines and prescribed drugs: a systematic review.

49. Drugs. 2001;61(15):2163-75. doi: 10.2165/00003495-200161150-00002. Interactions between herbal medicines and prescribed drugs: a systematic review. Izzo AA(1), Ernst E. Author information: (1)Department of Experimental Pharmacology, University of Naples 'Federico II', Naples, Italy. Despite