황련

Protoberberine alkaloids: A review of the gastroprotective effects, pharmacokinetics, and toxicity.

1. Phytomedicine. 2024 Apr;126:155444. doi: 10.1016/j.phymed.2024.155444. Epub 2024 Feb 10. Protoberberine alkaloids: A review of the gastroprotective effects, pharmacokinetics, and toxicity. Xiang ZD(1), Guan HD(1), Zhao X(1), Xie Q(1), Cai FJ(1), Xie ZJ(1), Dang R(1), Li ML(2), Wang CH(3). A

Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.

2. Drugs. 2023 Apr;83(5):403-427. doi: 10.1007/s40265-023-01841-4. Epub 2023 Mar 21. Overall and Sex-Specific Effect of Berberine for the Treatment of Dyslipidemia in Adults: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. Blais JE(1)(2), Huang X(1), Zhao JV(3).

Potential Therapeutic Effects of Natural Plant Compounds in Kidney Disease.

3. Molecules. 2021 Oct 9;26(20):6096. doi: 10.3390/molecules26206096. Potential Therapeutic Effects of Natural Plant Compounds in Kidney Disease. Avila-Carrasco L(1)(2), García-Mayorga EA(2), Díaz-Avila DL(2), Garza-Veloz I(1), Martinez-Fierro ML(1), González-Mateo GT(3)(4). Author information:

Mechanism and treatment of diarrhoea due to Vibrio cholerae and Escherichia coli: roles of drugs and prostaglandins.

4. Dan Med Bull. 1996 Apr;43(2):173-85. Mechanism and treatment of diarrhoea due to Vibrio cholerae and Escherichia coli: roles of drugs and prostaglandins. Rabbani GH(1). Author information: (1)International Centre for Diarrhoeal Disease Research, Clinical Sciences Division, Dhaka, Bangladesh.

Co-crystals of berberine with two natural polyphenols: synthesis, crystal structure and bacteriostasis on aquatic pathogens.

5. Bioorg Chem. 2026 Apr 21;177:109906. doi: 10.1016/j.bioorg.2026.109906. Online ahead of print. Co-crystals of berberine with two natural polyphenols: synthesis, crystal structure and bacteriostasis on aquatic pathogens. Chen ZC(1), Li JY(1), Teng JR(1), Wei HZ(1), Wen CC(1), Liu RX(2), Liu YC

Cost-effectiveness of statins, berberine, and combination for primary cardiovascular disease prevention in Scotland.

6. NPJ Cardiovasc Health. 2026 Apr 23;3(1):22. doi: 10.1038/s44325-026-00121-w. Cost-effectiveness of statins, berberine, and combination for primary cardiovascular disease prevention in Scotland. Xia Y(1), Leung K(2)(3)(4)(5), Zhao JV(6)(7). Author information: (1)School of Public Health, Li Ka

Potentiation of the antimycobacterial activity of bedaquiline, clofazimine, and doxycycline against Mycobacterium smegmatis by several natural product-based compounds is putatively via efflux inhibition.

7. Open Res Afr. 2026 Feb 22;8:23. doi: 10.12688/openresafrica.16071.2. eCollection 2025. Potentiation of the antimycobacterial activity of bedaquiline, clofazimine, and doxycycline against Mycobacterium smegmatis by several natural product-based compounds is putatively via efflux inhibition. C

Natural Alkaloids as Antimicrobial Agents: Mechanisms, Potentials and Challenges.

8. Molecules. 2026 Apr 5;31(7):1204. doi: 10.3390/molecules31071204. Natural Alkaloids as Antimicrobial Agents: Mechanisms, Potentials and Challenges. Zhang XZ(1)(2), Chen MX(1)(2), Hou R(3), Wang WQ(3), He ZD(1), You JS(1), Song X(1). Author information: (1)College of Pharmacy, Shenzhen Techno

Isolation, Identification and In Silico Evaluation of Novel Cholinesterase Inhibitors from Terminalia triptera Stapf.

9. Molecules. 2026 Mar 27;31(7):1113. doi: 10.3390/molecules31071113. Isolation, Identification and In Silico Evaluation of Novel Cholinesterase Inhibitors from Terminalia triptera Stapf. Phan TQ(1), Huang HT(2), Wang SL(3)(4), Nguyen DS(1), Doan MD(5), Pham THT(1), Phan TKT(1), Truong BP(1), Ng

Natural Products Targeting Angiogenesis and Tumor Microenvironment in Gastrointestinal Malignancies.

10. Cells. 2026 Mar 31;15(7):623. doi: 10.3390/cells15070623. Natural Products Targeting Angiogenesis and Tumor Microenvironment in Gastrointestinal Malignancies. Arslan I(1). Author information: (1)Faculty of Science, Molecular Biology and Genetics, Zonguldak Bülent Ecevit University, Zongulda

Retrospection of Argemone mexicana and its Derived Analogs as a Futuristic Approach Exhibiting Anticancer Potential.

11. Mini Rev Med Chem. 2026 Mar 16. doi: 10.2174/0113895575417548251208235008. Online ahead of print. Retrospection of Argemone mexicana and its Derived Analogs as a Futuristic Approach Exhibiting Anticancer Potential. Kulshrestha S(1), Saraswat I(1), Goel A(1). Author information: (1)Departmen

Pharmacological advances in multi-targeted strategies for type 2 diabetes mellitus: a systematic perspective based on traditional Chinese medicine.

12. Front Pharmacol. 2026 Feb 20;16:1732134. doi: 10.3389/fphar.2025.1732134. eCollection 2025. Pharmacological advances in multi-targeted strategies for type 2 diabetes mellitus: a systematic perspective based on traditional Chinese medicine. Zhao YL(#)(1), Liao JB(#)(1), Pang PP(2), Li JY(3),

Molecular landscape of Berberine's therapeutic potential in gastrointestinal disorders.

13. J Tradit Chin Med. 2026 Feb;46(1):245-256. doi: 10.19852/j.cnki.jtcm.2026.01.024. Molecular landscape of Berberine's therapeutic potential in gastrointestinal disorders. Wu Y(1), Yinghui LI(1), Heng L(1), Shangbin X(2). Author information: (1)Taihe Hospital Rehabilitation Center, Taihe Hosp

Natural compounds as immune checkpoint inhibitors in melanoma: a systematic review.

14. Naunyn Schmiedebergs Arch Pharmacol. 2026 Feb 20. doi: 10.1007/s00210-026-05120-3. Online ahead of print. Natural compounds as immune checkpoint inhibitors in melanoma: a systematic review. Samieefar S(1), Arasteh O(2), Yeganeh Khorasanii N(1), Abedi F(2), Hosseinzadeh HR(3), Hosseinzadeh H

Medication targeting to subcellular organelles: Emphasizing mitochondria as a therapeutic marvel-Current situation and future prospects.

15. Exp Cell Res. 2025 Jul 15;450(2):114647. doi: 10.1016/j.yexcr.2025.114647. Epub 2025 Jun 13. Medication targeting to subcellular organelles: Emphasizing mitochondria as a therapeutic marvel-Current situation and future prospects. Alzhrani RF(1), Alhowyan AA(1), Taha EI(1), Attia SM(2), Salam

Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development.

23. Pharmacol Res. 2023 Oct;196:106925. doi: 10.1016/j.phrs.2023.106925. Epub 2023 Sep 14. Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development. Wang L(1), Yan Y(1), Wu L(1), Peng J(2). Author information: (1)School of Pharmacy, Anhui Universi

Evaluation of berberine efficacy in reducing the effects of aflatoxin B1 and ochratoxin A added to male broiler rations.

43. Poult Sci. 2021 Feb;100(2):797-809. doi: 10.1016/j.psj.2020.10.040. Epub 2020 Nov 5. Evaluation of berberine efficacy in reducing the effects of aflatoxin B1 and ochratoxin A added to male broiler rations. Malekinezhad P(1), Ellestad LE(2), Afzali N(3), Farhangfar SH(4), Omidi A(5), Mohamma

Effects of sulforaphane in the central nervous system.

12. Eur J Pharmacol. 2019 Jun 15;853:153-168. doi: 10.1016/j.ejphar.2019.03.010. Epub 2019 Mar 8. Effects of sulforaphane in the central nervous system. Huang C(1), Wu J(2), Chen D(3), Jin J(3), Wu Y(1), Chen Z(4). Author information: (1)Department of Pharmacology, School of Pharmacy, Nantong Un

Maxillary palp odorant-binding proteins as key mediators of bitter taste and molecular targets for cockroach control.

17. J Adv Res. 2026 Apr 27:S2090-1232(26)00366-8. doi: 10.1016/j.jare.2026.04.063. Online ahead of print. Maxillary palp odorant-binding proteins as key mediators of bitter taste and molecular targets for cockroach control. Feng HY(1), Zhao YQ(1), Tao-Yang(1), Liu XY(1), Wang J(1), Wu C(1), Zhao

Drug-Loaded Extracellular Vesicle-Based Drug Delivery: Advances, Loading Strategies, Therapeutic Applications, and Clinical Challenges.

8. Pharmaceutics. 2025 Dec 29;18(1):45. doi: 10.3390/pharmaceutics18010045. Drug-Loaded Extracellular Vesicle-Based Drug Delivery: Advances, Loading Strategies, Therapeutic Applications, and Clinical Challenges. Dieu LL(1), Kazsoki A(1), Zelkó R(1). Author information: (1)University Pharmacy Dep

[Determination of moistening endpoint of Phellodendri Chinensis Cortex based on multi-source data fusion].

20. Zhongguo Zhong Yao Za Zhi. 2025 Sep;50(18):5159-5167. doi: 10.19540/j.cnki.cjcmm.20250513.303. [Determination of moistening endpoint of Phellodendri Chinensis Cortex based on multi-source data fusion]. [Article in Chinese] Hua ST(1), He SF(2), Dai SQ(1), Liu W(3), Zhang AL(2), Liu LF(1), Lu

The advancements in targeted therapeutic strategies for breast cancer via intervention of natural molecules: An insight into cellular and molecular mechanisms.

12. Pathol Res Pract. 2026 Feb;278:156338. doi: 10.1016/j.prp.2025.156338. Epub 2025 Dec 23. The advancements in targeted therapeutic strategies for breast cancer via intervention of natural molecules: An insight into cellular and molecular mechanisms. Kaleem M(1), Gangane P(2), Mujtaba MA(3),

A comprehensive compendium of berberine: sources, chemistry, and pharmacological activities.

28. J Sci Food Agric. 2025 Dec 19. doi: 10.1002/jsfa.70394. Online ahead of print. A comprehensive compendium of berberine: sources, chemistry, and pharmacological activities. Mohapatra N(1), Singh TG(1), Kumar M(1), Awasthi A(1). Author information: (1)Chitkara College of Pharmacy, Chitkara Uni

Comparative efficacy of diverse therapeutic regimens for small intestinal bacterial overgrowth: a systematic network meta-analysis.

44. Ther Adv Gastroenterol. 2025 Dec 11;18:17562848251399033. doi: 10.1177/17562848251399033. eCollection 2025. Comparative efficacy of diverse therapeutic regimens for small intestinal bacterial overgrowth: a systematic network meta-analysis. Zhang Q(1), Li H(2), Chen C(2), Li M(2), Song J(2),

Discovering bioactive pharmaceuticals from natural products for type 2 diabetes mellitus using network pharmacology, molecular docking, and molecular dynamics.

1. Sci Rep. 2025 Dec 5;15(1):43205. doi: 10.1038/s41598-025-27173-9. Discovering bioactive pharmaceuticals from natural products for type 2 diabetes mellitus using network pharmacology, molecular docking, and molecular dynamics. Rahmani B(1)(2)(3), Akbari H(4), Esmaeili H(5), Solaimanian S(6), Mo