지실 (비터 오렌지)

Effect of Moro orange juice extract supplementation in weight management in adults: A systematic review and meta-analysis.

1. Nutr Health. 2026 Mar;32(2):455-464. doi: 10.1177/02601060251374379. Epub 2025 Sep 16. Effect of Moro orange juice extract supplementation in weight management in adults: A systematic review and meta-analysis. Campos CM(1), Gallo Ruelas M(2), Silva GHD(1), Lima FR(3), Holanda DF(4). Author i

A meta-analysis on use of agro-industrial by-products rich in polyphenols in dairy small ruminant nutrition.

2. Animal. 2025 Jul;19 Suppl 2:101522. doi: 10.1016/j.animal.2025.101522. Epub 2025 Apr 21. A meta-analysis on use of agro-industrial by-products rich in polyphenols in dairy small ruminant nutrition. Nudda A(1), Carta S(2), Correddu F(1), Caratzu MF(1), Cesarani A(3), Hidalgo J(4), Pulina G(1)

The effects of citrus flavonoids supplementation on endothelial function: A systematic review and dose-response meta-analysis of randomized clinical trials.

3. Phytother Res. 2024 Jun;38(6):2847-2859. doi: 10.1002/ptr.8190. Epub 2024 Apr 1. The effects of citrus flavonoids supplementation on endothelial function: A systematic review and dose-response meta-analysis of randomized clinical trials. Jalili F(1), Moradi S(2), Talebi S(3)(4), Mehrabani S(5)

Orange juice intake and lipid profile: a systematic review and meta-analysis of randomised controlled trials.

4. J Nutr Sci. 2023 Mar 17;12:e37. doi: 10.1017/jns.2023.22. eCollection 2023. Orange juice intake and lipid profile: a systematic review and meta-analysis of randomised controlled trials. Amini MR(1), Sheikhhossein F(2), Bazshahi E(3), Rahimi H(4), Ghalandari H(4), Ghaedi E(2), Askarpour M(5).

A review of citrus plants as functional foods and dietary supplements for human health, with an emphasis on meta-analyses, clinical trials, and their chemical composition.

5. Clin Nutr ESPEN. 2023 Apr;54:311-336. doi: 10.1016/j.clnesp.2023.02.001. Epub 2023 Feb 7. A review of citrus plants as functional foods and dietary supplements for human health, with an emphasis on meta-analyses, clinical trials, and their chemical composition. Pasdaran A(1), Hamedi A(2), Sh

The Safety and Efficacy of Citrus aurantium (Bitter Orange) Extracts and p-Synephrine: A Systematic Review and Meta-Analysis.

6. Nutrients. 2022 Sep 28;14(19):4019. doi: 10.3390/nu14194019. The Safety and Efficacy of Citrus aurantium (Bitter Orange) Extracts and p-Synephrine: A Systematic Review and Meta-Analysis. Koncz D(1), Tóth B(1)(2), Bahar MA(1)(3), Roza O(4), Csupor D(1)(2)(4). Author information: (1)Institute o

Effects of hesperidin on anti-inflammatory and antioxidant response in healthy people: a meta-analysis and meta-regression.

7. Int J Environ Health Res. 2023 Dec;33(12):1390-1405. doi: 10.1080/09603123.2022.2093841. Epub 2022 Jun 28. Effects of hesperidin on anti-inflammatory and antioxidant response in healthy people: a meta-analysis and meta-regression. Buzdağlı Y(1), Eyipınar CD(2), Kacı FN(3)(4), Tekin A(5). Aut

Effects of chronic consumption of specific fruit (berries, cherries and citrus) on cognitive health: a systematic review and meta-analysis of randomised controlled trials.

8. Eur J Clin Nutr. 2023 Jan;77(1):7-22. doi: 10.1038/s41430-022-01138-x. Epub 2022 Apr 20. Effects of chronic consumption of specific fruit (berries, cherries and citrus) on cognitive health: a systematic review and meta-analysis of randomised controlled trials. Wang Y(1), Haskell-Ramsay C(2),

Effects of orange juice intake on cardiovascular risk factors: A systematic review and meta-analysis of randomized controlled clinical trials.

9. Phytother Res. 2021 Oct;35(10):5427-5439. doi: 10.1002/ptr.7173. Epub 2021 May 31. Effects of orange juice intake on cardiovascular risk factors: A systematic review and meta-analysis of randomized controlled clinical trials. Motallaei M(1)(2), Ramezani-Jolfaie N(3), Mohammadi M(3), Shams-Rad

The effects of hesperidin supplementation or orange juice consumption on anthropometric measures in adults: A meta-analysis of randomized controlled clinical trials.

10. Clin Nutr ESPEN. 2021 Jun;43:148-157. doi: 10.1016/j.clnesp.2021.03.036. Epub 2021 Apr 17. The effects of hesperidin supplementation or orange juice consumption on anthropometric measures in adults: A meta-analysis of randomized controlled clinical trials. Djafari F(1), Shahavandi M(1), Ami

Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability.

11. Food Funct. 2026 Mar 9;17(5):2292-2310. doi: 10.1039/d5fo04536c. Impact of the orange juice fruit matrix on postprandial glycemia: a crossover randomized trial in healthy young men with post hoc analysis of interindividual response variability. García-Conesa MT(1), García-Villalba R(1), Frut

Assessment of the Intestinal CYP3A Contribution to Drug Interactions with Extended-Release Tacrolimus (LCPT) Using Grapefruit Juice.

12. Clin Pharmacol Drug Dev. 2026 Jan;15(1):e70016. doi: 10.1002/cpdd.70016. Assessment of the Intestinal CYP3A Contribution to Drug Interactions with Extended-Release Tacrolimus (LCPT) Using Grapefruit Juice. Alabi A(1), Kerr JS(2), Shah M(3), Khan A(3), Ma JD(4), Suhandynata RT(4), Momper JD(5

Lime-based supplement reduces calcium oxalate stone recurrence: A multicenter randomized controlled trial.

13. PLoS One. 2025 Dec 5;20(12):e0336892. doi: 10.1371/journal.pone.0336892. eCollection 2025. Lime-based supplement reduces calcium oxalate stone recurrence: A multicenter randomized controlled trial. Dissayabutra T(1)(2), Anegkamol W(1), Ratchanon S(3), Ungjaroenwathana W(4), Klinhom T(4), Sa

Transcutaneous Peripheral Nerve Stimulation for Essential Tremor: A Randomized Clinical Trial.

14. JAMA Neurol. 2025 Dec 1;82(12):1235-1242. doi: 10.1001/jamaneurol.2025.3905. Transcutaneous Peripheral Nerve Stimulation for Essential Tremor: A Randomized Clinical Trial. Ondo WG(1), Lv W(2), Zhu X(3), Hu Y(4), Isaacson SH(5), Yuan Y(6), Espay AJ(7), Kreitzman D(8), Kuo SH(9), Brillman S(10

The effect of Citrus aurantium inhalation aromatherapy on chemotherapy-induced nausea and vomiting in breast cancer patients: a randomized controlled trial.

15. BMC Complement Med Ther. 2025 Oct 7;25(1):359. doi: 10.1186/s12906-025-05052-0. The effect of Citrus aurantium inhalation aromatherapy on chemotherapy-induced nausea and vomiting in breast cancer patients: a randomized controlled trial. Tabei P(1), Molazem Z(2), Rivaz M(3), Maghami PG(1), Ahm

Multi-omics analysis of a prebiotic intervention with pectin in lipid transfer proteins (LTPs) allergic patients.

49. Carbohydr Polym. 2025 Dec 1;369:124236. doi: 10.1016/j.carbpol.2025.124236. Epub 2025 Aug 14. Multi-omics analysis of a prebiotic intervention with pectin in lipid transfer proteins (LTPs) allergic patients. Gómez F(1), Pérez-Sánchez N(2), Macías-Camero A(3), Núñez R(4), Contreras N(3), Cañ

Single-dose Versus 3-day Antimicrobial Prophylaxis in Transurethral Resection or Photoselective Vaporization of the Prostate: A Multicenter, Randomized, Placebo Controlled Trial (CITrUS Trial).

15. Eur Urol Focus. 2026 Mar;12(2):174-181. doi: 10.1016/j.euf.2025.08.009. Epub 2025 Sep 12. Single-dose Versus 3-day Antimicrobial Prophylaxis in Transurethral Resection or Photoselective Vaporization of the Prostate: A Multicenter, Randomized, Placebo Controlled Trial (CITrUS Trial). Bausch

Acute glycaemic response of orange juice consumption with breakfast in individuals with type 2 diabetes: a randomized cross-over trial.

3. Nutr Diabetes. 2025 Jul 9;15(1):31. doi: 10.1038/s41387-025-00385-8. Acute glycaemic response of orange juice consumption with breakfast in individuals with type 2 diabetes: a randomized cross-over trial. Verboven K(1)(2), Van Ryckeghem L(3)(4), Schweiggert R(5), Steingass CB(5), Gojevic T(3)

Effect of Citrus Aurantium L. on pain and blood pressure in patients undergoing hand reconstructive surgery.

36. Pain Manag. 2025 Aug;15(8):491-500. doi: 10.1080/17581869.2025.2515814. Epub 2025 Jul 6. Effect of Citrus Aurantium L. on pain and blood pressure in patients undergoing hand reconstructive surgery. Askari F(1), Ghaffari F(2), Alaee N(1)(3), Naseri M(3)(4)(5), Tayanloo-Beik A(6). Author inf

Effects of a flavonoid-enriched orange juice on antioxidant capacity, lipid profile, and inflammation in obese patients: A randomized placebo-controlled trial.

43. Food Res Int. 2025 Oct;217:116759. doi: 10.1016/j.foodres.2025.116759. Epub 2025 Jun 10. Effects of a flavonoid-enriched orange juice on antioxidant capacity, lipid profile, and inflammation in obese patients: A randomized placebo-controlled trial. Navajas-Porras B(1), Bosch-Sierra N(2), Va

Diosmetin overcomes resistance to cisplatin in ovarian cancer by suppressing the MAPK signaling pathway.

41. Med Oncol. 2026 Apr 20;43(5):181. doi: 10.1007/s12032-026-03293-8. Diosmetin overcomes resistance to cisplatin in ovarian cancer by suppressing the MAPK signaling pathway. Nie J(#)(1), Jiang H(#)(2), Zhou R(3), Gong R(1), Xu W(1), Zhang P(1), Lu L(4), Lyu L(5). Author information: (1)Depart

TRPM2 Channel Involvement in the Hesperidin-Mediated Potentiation of Cisplatin's Antitumor Action in Laryngeal Carcinoma Cells.

1. Int J Mol Sci. 2026 Jan 23;27(3):1141. doi: 10.3390/ijms27031141. TRPM2 Channel Involvement in the Hesperidin-Mediated Potentiation of Cisplatin's Antitumor Action in Laryngeal Carcinoma Cells. Çınar R(1), Yıldızhan K(2), Altıner Hİ(3), Yağcı T(3). Author information: (1)Department of Biophys

Investigation of the Anticancer Effects and Senescence Induction of Hesperetin Combined with Cisplatin in Hepatocellular Carcinoma and Embryonic Fibroblast Cell Lines.

11. Asian Pac J Cancer Prev. 2026 Feb 1;27(2):557-568. doi: 10.31557/APJCP.2026.27.2.557. Investigation of the Anticancer Effects and Senescence Induction of Hesperetin Combined with Cisplatin in Hepatocellular Carcinoma and Embryonic Fibroblast Cell Lines. Artanti AN(1)(2)(3), Jenie RI(3)(4),

Assessment of co-toxicity and synergistic action mechanism of essential oils derived from Citrus plants against Anopheles stephensi and Culex quinquefasciatus.

44. Parasitol Int. 2026 Aug;113:103241. doi: 10.1016/j.parint.2026.103241. Epub 2026 Jan 23. Assessment of co-toxicity and synergistic action mechanism of essential oils derived from Citrus plants against Anopheles stephensi and Culex quinquefasciatus. Sharma S(1), Gupta S(1), Chaudhary M(1), L

p-Synephrine, synergistically with Gastrodin, alleviates reserpine-induced depressive pathologies by binding to MT(1) receptor and activating ERK/CREB/BDNF pathway.

5. Phytomedicine. 2026 Jan;150:157757. doi: 10.1016/j.phymed.2025.157757. Epub 2026 Jan 2. p-Synephrine, synergistically with Gastrodin, alleviates reserpine-induced depressive pathologies by binding to MT(1) receptor and activating ERK/CREB/BDNF pathway. Gao HL(1), Chen H(2), Zhang XY(3), Xu T

Synergistic Anticancer and Certain Biochemical Events Impact ER+ MCF-7 Breast Cancer Cells by Local "Citrullus colocynthis-Lemon Fruit" Hydroethanolic Extract Combination.

35. Asian Pac J Cancer Prev. 2025 Dec 1;26(12):4617-4622. doi: 10.31557/APJCP.2025.26.12.4617. Synergistic Anticancer and Certain Biochemical Events Impact ER+ MCF-7 Breast Cancer Cells by Local "Citrullus colocynthis-Lemon Fruit" Hydroethanolic Extract Combination. Sabbar AG(1), Mohsin AA(1).

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans.

9. Clin Pharmacol Ther. 2026 Apr;119(4):953-963. doi: 10.1002/cpt.70165. Epub 2025 Dec 14. Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans. Aurinsalo L(1)(2)(3), Lapatto-Reiniluoto O(1)(2)(3)(4)

In vitro synergy analysis of the combination of Citrus aurantium bergamia (Risso & Poiteau, 1826), ivermectin, and nitroxinil against gastrointestinal nematodes of sheep.

27. Vet Parasitol Reg Stud Reports. 2025 Nov;66:101384. doi: 10.1016/j.vprsr.2025.101384. Epub 2025 Nov 15. In vitro synergy analysis of the combination of Citrus aurantium bergamia (Risso & Poiteau, 1826), ivermectin, and nitroxinil against gastrointestinal nematodes of sheep. Garbin VP(1), Yo

Combined Hesperidin and Doxorubicin Treatment Induces Apoptosis and Modulates Inflammatory Cytokines in HeLa Cervical Cancer Cells.

38. Int J Mol Sci. 2025 Sep 8;26(17):8753. doi: 10.3390/ijms26178753. Combined Hesperidin and Doxorubicin Treatment Induces Apoptosis and Modulates Inflammatory Cytokines in HeLa Cervical Cancer Cells. Özdemir İ(1), Afşin Y(2), Tuncer MC(3), Öztürk Ş(4). Author information: (1)IVF Center, Privat

Efficacy of Crataegus Extract Mixture on Body Fat and Lipid Profiles in Overweight Adults: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial.

43. Nutrients. 2024 Feb 8;16(4):494. doi: 10.3390/nu16040494. Efficacy of Crataegus Extract Mixture on Body Fat and Lipid Profiles in Overweight Adults: A 12-Week, Randomized, Double-Blind, Placebo-Controlled Trial. Song J(1), Kim DY(2), Lee HS(2), Rhee SY(3)(4), Lim H(2)(5). Author information