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Efficacy evaluation of standardized Boswellia serrata extract (Aflapin(Ⓡ)) in osteoarthritis: A systematic review and sub-group meta-analysis study.

1. Explore (NY). 2024 Sep-Oct;20(5):102983. doi: 10.1016/j.explore.2024.02.001. Epub 2024 Feb 10. Efficacy evaluation of standardized Boswellia serrata extract (Aflapin(Ⓡ)) in osteoarthritis: A systematic review and sub-group meta-analysis study. Dubey V(1), Kheni D(2), Sureja V(2). Author info

Interventions for treating collagenous colitis.

2. Cochrane Database Syst Rev. 2017 Nov 11;11(11):CD003575. doi: 10.1002/14651858.CD003575.pub6. Interventions for treating collagenous colitis. Kafil TS(1), Nguyen TM, Patton PH, MacDonald JK, Chande N, McDonald JW. Author information: (1)Department of Medicine, University of Western Ontario, L

Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.

3. Br J Sports Med. 2018 Feb;52(3):167-175. doi: 10.1136/bjsports-2016-097333. Epub 2017 Oct 10. Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis. Liu X(1)(2), Machado GC(3), Eyles JP(1)(2)(4), Ravi V(1)(2), Hunter DJ(1)(2). Author information: (1)Departmen

Interventions for treating collagenous colitis.

4. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD003575. doi: 10.1002/14651858.CD003575.pub4. Interventions for treating collagenous colitis. Chande N(1), McDonald JW, MacDonald JK. Author information: (1)LHSC--South Street Hospital, Mailbox 55, 375 South Street, London, Ontario, CANADA. nchand

Efficacy and Safety of Boswellia serrata and Apium graveolens L. Extract Against Knee Osteoarthritis and Cartilage Degeneration: A Randomized, Double-blind, Multicenter, Placebo-Controlled Clinical Trial.

5. Pharm Res. 2025 Feb;42(2):249-269. doi: 10.1007/s11095-025-03818-2. Epub 2025 Jan 28. Efficacy and Safety of Boswellia serrata and Apium graveolens L. Extract Against Knee Osteoarthritis and Cartilage Degeneration: A Randomized, Double-blind, Multicenter, Placebo-Controlled Clinical Trial. V

Efficacy and safety evaluation of Boswellia serrata and Curcuma longa extract combination in the management of chronic lower back pain: A randomised, double-blind, placebo-controlled clinical study.

6. Explore (NY). 2025 Jan-Feb;21(1):103099. doi: 10.1016/j.explore.2024.103099. Epub 2024 Dec 18. Efficacy and safety evaluation of Boswellia serrata and Curcuma longa extract combination in the management of chronic lower back pain: A randomised, double-blind, placebo-controlled clinical study.

A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study.

7. J Am Nutr Assoc. 2025 Jul;44(5):375-386. doi: 10.1080/27697061.2024.2438894. Epub 2024 Dec 19. A Standardized Boswellia serrata Extract Improves Knee Joint Function and Cartilage Morphology in Human Volunteers with Mild to Moderate Osteoarthritis in a Randomized Placebo-Controlled Study. Kum

Investigating the Additive Effects of Loxacon(®) Food Supplement Capsules in Patients with Knee Osteoarthritis. A Multicenter, Randomized, Double-Blind, Controlled, Crossover, Follow-Up, Three-Arm Study.

8. J Med Food. 2024 Dec;27(12):1253-1258. doi: 10.1089/jmf.2024.0133. Epub 2024 Oct 24. Investigating the Additive Effects of Loxacon(®) Food Supplement Capsules in Patients with Knee Osteoarthritis. A Multicenter, Randomized, Double-Blind, Controlled, Crossover, Follow-Up, Three-Arm Study. Ben

Pharmacokinetics of a Natural Self-emulsifying Reversible Hybrid-Hydrogel (N'SERH) Formulation of Full-Spectrum Boswellia serrata Oleo-Gum Resin Extract: Randomised Double-Blinded Placebo-Controlled Crossover Study.

9. Biol Pharm Bull. 2024;47(9):1583-1593. doi: 10.1248/bpb.b24-00306. Pharmacokinetics of a Natural Self-emulsifying Reversible Hybrid-Hydrogel (N'SERH) Formulation of Full-Spectrum Boswellia serrata Oleo-Gum Resin Extract: Randomised Double-Blinded Placebo-Controlled Crossover Study. Joseph A(1

The role of nutraceuticals in the management of temporomandibular disorders.

10. J Complement Integr Med. 2024 Jul 4;21(4):540-547. doi: 10.1515/jcim-2023-0394. eCollection 2024 Dec 1. The role of nutraceuticals in the management of temporomandibular disorders. Di Giacomo P(1), Forte G(2), Capogna I(1), Casagrande M(2), Di Paolo C(1). Author information: (1)Department of

A Nutraceutical Combination of Bromelain and Boswellia Serrata Casperome® in Siben®: Effects on the Postoperative Course of Inguinal Hernioplasty with Mesh at One Year Follow up. A Randomized Multicentric Study.

11. Ann Ital Chir. 2024;95(3):347-352. doi: 10.62713/aic.3509. A Nutraceutical Combination of Bromelain and Boswellia Serrata Casperome® in Siben®: Effects on the Postoperative Course of Inguinal Hernioplasty with Mesh at One Year Follow up. A Randomized Multicentric Study. De Luca GM(1), De Luc

[Comparative efficacy of a combination of undenatured type II collagen, Boswellic acids, methylsulfonylmethane, vitamins C and D(3) and a combination of chondroitin sulfate and glucosamine hydrochloride in the treatment of primary osteoarthritis of the knee joint].

12. Ter Arkh. 2023 Dec 28;95(12):1141-1150. doi: 10.26442/00403660.2023.12.202540. [Comparative efficacy of a combination of undenatured type II collagen, Boswellic acids, methylsulfonylmethane, vitamins C and D(3) and a combination of chondroitin sulfate and glucosamine hydrochloride in the trea

Efficacy of Boswellia serrata Extract and/or an Omega-3-Based Product for Improving Pain and Function in People Older Than 40 Years with Persistent Knee Pain: A Randomized Double-Blind Controlled Clinical Trial.

13. Nutrients. 2023 Sep 3;15(17):3848. doi: 10.3390/nu15173848. Efficacy of Boswellia serrata Extract and/or an Omega-3-Based Product for Improving Pain and Function in People Older Than 40 Years with Persistent Knee Pain: A Randomized Double-Blind Controlled Clinical Trial. Pérez-Piñero S(1), M

Evaluation of the effectiveness of topical oily solution containing frankincense extract in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial.

14. BMC Res Notes. 2023 Mar 4;16(1):28. doi: 10.1186/s13104-023-06291-5. Evaluation of the effectiveness of topical oily solution containing frankincense extract in the treatment of knee osteoarthritis: a randomized, double-blind, placebo-controlled clinical trial. Mohsenzadeh A(1), Karimifar M(

A comprehensive review of Glycyrrhiza glabra in the management of rheumatoid arthritis: ethnopharmacology, pharmacological mechanisms and synergistic therapeutic strategies.

15. J Ethnopharmacol. 2026 Feb 10;356:120827. doi: 10.1016/j.jep.2025.120827. Epub 2025 Oct 31. A comprehensive review of Glycyrrhiza glabra in the management of rheumatoid arthritis: ethnopharmacology, pharmacological mechanisms and synergistic therapeutic strategies. Prajapati K(1), Mishra R(

Anti-proliferative, Pro-apoptotic, and Chemosensitizing Potential of 3-Acetyl-11-keto-β-boswellic Acid (AKBA) Against Prostate Cancer Cells.

33. Mol Biotechnol. 2025 Feb;67(2):746-761. doi: 10.1007/s12033-024-01089-7. Epub 2024 Mar 19. Anti-proliferative, Pro-apoptotic, and Chemosensitizing Potential of 3-Acetyl-11-keto-β-boswellic Acid (AKBA) Against Prostate Cancer Cells. Verma M(1), Fatima S(1), Saeed M(2), Ansari IA(3). Author i

A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee.

37. J Med Food. 2018 May;21(5):511-520. doi: 10.1089/jmf.2017.0065. Epub 2018 Apr 30. A Placebo-Controlled Double-Blind Study Demonstrates the Clinical Efficacy of a Novel Herbal Formulation for Relieving Joint Discomfort in Human Subjects with Osteoarthritis of Knee. Karlapudi V(1), Prasad Mun

Evaluation of Antimycobacterial and Synergistic Activity of Plants Selected Based on Cheminformatic Parameters.

41. Iran Biomed J. 2018 Nov;22(6):401-7. doi: 10.29252/.22.6.401. Epub 2018 Mar 7. Evaluation of Antimycobacterial and Synergistic Activity of Plants Selected Based on Cheminformatic Parameters. Rahgozar N(1)(2), Bakhshi Khaniki G(1), Sardari S(2). Author information: (1)Department of Agricultur

Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats.

28. Int J Mol Med. 2016 Jun;37(6):1501-10. doi: 10.3892/ijmm.2016.2571. Epub 2016 Apr 20. Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats. Chen M(1), Wang M(1), Yang Q(1), Wang M(2), Wang Z(2), Z

Co-administration of 3-Acetyl-11-Keto-Beta-Boswellic Acid Potentiates the Protective Effect of Celecoxib in Lipopolysaccharide-Induced Cognitive Impairment in Mice: Possible Implication of Anti-inflammatory and Antiglutamatergic Pathways.

33. J Mol Neurosci. 2016 May;59(1):58-67. doi: 10.1007/s12031-016-0734-7. Epub 2016 Mar 16. Co-administration of 3-Acetyl-11-Keto-Beta-Boswellic Acid Potentiates the Protective Effect of Celecoxib in Lipopolysaccharide-Induced Cognitive Impairment in Mice: Possible Implication of Anti-inflammato

Warfarin interactions with medicinal herbs.

34. Nat Prod Commun. 2014 Aug;9(8):1211-6. Warfarin interactions with medicinal herbs. Milić N, Milosević N, Golocorbin Kon S, Bozić T, Abenavoli L, Borrelli F. Recognition of the adverse effects of medicinal herbs is not routine and the reports on such effects are even less frequent in clinical

Caspase mediated synergistic effect of Boswellia serrata extract in combination with doxorubicin against human hepatocellular carcinoma.

35. Biomed Res Int. 2014;2014:294143. doi: 10.1155/2014/294143. Epub 2014 Aug 7. Caspase mediated synergistic effect of Boswellia serrata extract in combination with doxorubicin against human hepatocellular carcinoma. Khan MA(1), Singh M(2), Khan MS(2), Najmi AK(1), Ahmad S(2). Author informatio

Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers.

42. Planta Med. 2004 Dec;70(12):1155-60. doi: 10.1055/s-2004-835844. Effect of food intake on the bioavailability of boswellic acids from a herbal preparation in healthy volunteers. Sterk V(1), Büchele B, Simmet T. Author information: (1)Department of Pharmacology of Natural Products & Clinical

Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis.

33. Complement Ther Med. 2026 Mar;96:103256. doi: 10.1016/j.ctim.2025.103256. Epub 2025 Oct 12. Evaluating the efficacy and safety of Curcuma longa, Boswellia serrata, and their mixed formulation in treating knee osteoarthritis: A systematic review and network meta-analysis. Inprasit C(1), Buny

Chemical Constituents and Pharmacological Properties of Frankincense: Implications for Anticancer Therapy.

41. Chin J Integr Med. 2024 Aug;30(8):759-767. doi: 10.1007/s11655-024-4105-x. Epub 2024 May 31. Chemical Constituents and Pharmacological Properties of Frankincense: Implications for Anticancer Therapy. Wu YR(1), Xiong W(2), Dong YJ(1), Chen X(3), Zhong YY(1), He XL(1), Wang YJ(4), Lin QF(2),

Possible role of Unani Pharmacology in COVID-19 - a narrative review.

18. Rev Environ Health. 2020 Nov 9;36(3):391-396. doi: 10.1515/reveh-2020-0106. Print 2021 Sep 27. Possible role of Unani Pharmacology in COVID-19 - a narrative review. Alam MA(1), Gani MA(2), Shama G(3), Sofi G(2), Quamri MA(1). Author information: (1)Department of Medicine, National Institute

Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis.

36. BMC Complement Med Ther. 2020 Jul 17;20(1):225. doi: 10.1186/s12906-020-02985-6. Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis. Yu G(1), Xiang W(2)(3), Zhang T(4)(5), Zeng L(6), Yang K(7), Li J(8). Author information: (1)T

Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis.

49. Phytother Res. 2017 Nov;31(11):1676-1685. doi: 10.1002/ptr.5910. Epub 2017 Sep 5. Oral herbal medicines marketed in Brazil for the treatment of osteoarthritis: A systematic review and meta-analysis. Del Grossi Moura M(1), Lopes LC(1), Biavatti MW(2), Kennedy SA(3), de Oliveira E Silva MC(1)

Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases.

17. J Crohns Colitis. 2015 Jan;9(1):86-106. doi: 10.1093/ecco-jcc/jju007. Epub 2014 Nov 28. Systematic review of complementary and alternative medicine treatments in inflammatory bowel diseases. Langhorst J(1), Wulfert H(2), Lauche R(3), Klose P(2), Cramer H(3), Dobos GJ(2), Korzenik J(4). Aut