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The Effect of Nigella sativa Supplementation on Cardiometabolic Health in Patients With Metabolic Diseases: A GRADE-Assessed Systematic Review and Meta-Analysis.

1. Endocrinol Diabetes Metab. 2026 Mar;9(2):e70207. doi: 10.1002/edm2.70207. The Effect of Nigella sativa Supplementation on Cardiometabolic Health in Patients With Metabolic Diseases: A GRADE-Assessed Systematic Review and Meta-Analysis. Musazadeh V(1)(2), Jahangir M(3), Mahmoudinezhad M(4)(5),

Systematic review of prophylactic antibacterial agents for radiation-induced oral mucositis in head and neck cancer.

2. Support Care Cancer. 2026 Feb 23;34(3):234. doi: 10.1007/s00520-026-10439-x. Systematic review of prophylactic antibacterial agents for radiation-induced oral mucositis in head and neck cancer. Alicea DS(1), Han M(2), Islam Z(3), Schwartz R(4), Ow TJ(5), Mehta V(5), Garg M(6), McLellan BN(3),

A holistic guide to effective prevention and treatment for kidney stones: a systematic review exploring anti-urolithiasis approaches.

3. Naunyn Schmiedebergs Arch Pharmacol. 2026 Feb;399(3):3235-3284. doi: 10.1007/s00210-025-04658-y. Epub 2025 Oct 20. A holistic guide to effective prevention and treatment for kidney stones: a systematic review exploring anti-urolithiasis approaches. Allam AT(1), El-Dessouki AM(2), El-Shiekh RA

The efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review.

4. BMC Complement Med Ther. 2025 Sep 30;25(1):341. doi: 10.1186/s12906-025-05059-7. The efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review. Li E(1), Maunder A(2), Liu J(2), Pandey C(2), Cave A(2), O'Fee A(2)

Effects of Nigella sativa and its constituents on inflammatory markers in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis.

5. Inflammopharmacology. 2025 Sep;33(9):5067-5083. doi: 10.1007/s10787-025-01911-x. Epub 2025 Aug 21. Effects of Nigella sativa and its constituents on inflammatory markers in ovalbumin-induced asthma model: a preclinical systematic review and meta-analysis. Ghobadi H(1), Mohammadzadeh E(1), As

Does Nigella sativa supplementation improve cardiovascular disease risk factors? A comprehensive GRADE-assessed systematic review and dose-response meta-analysis of 82 randomized controlled trials.

6. Pharmacol Res. 2025 Sep;219:107882. doi: 10.1016/j.phrs.2025.107882. Epub 2025 Jul 24. Does Nigella sativa supplementation improve cardiovascular disease risk factors? A comprehensive GRADE-assessed systematic review and dose-response meta-analysis of 82 randomized controlled trials. Jafari

Efficacy and safety of phytotherapy and anthroposophic medicine in bronchial asthma: A systematic review.

7. Respir Med. 2025 Aug-Sep;245:108202. doi: 10.1016/j.rmed.2025.108202. Epub 2025 Jun 7. Efficacy and safety of phytotherapy and anthroposophic medicine in bronchial asthma: A systematic review. Braunwalder C(1), Ertl J(2), Wullschleger M(2), Timm E(2), Wolf U(2). Author information: (1)Instit

Effects of black seed (Nigella sativa L.) on cardiometabolic indices in type 2 diabetic patients: A systematic review and meta-analysis of RCTs.

8. Complement Ther Med. 2025 Jun;90:103174. doi: 10.1016/j.ctim.2025.103174. Epub 2025 Apr 8. Effects of black seed (Nigella sativa L.) on cardiometabolic indices in type 2 diabetic patients: A systematic review and meta-analysis of RCTs. Karimi M(1), Pirzad S(2), Pourfaraji SMA(3), Sedgi FM(4),

Alleviating effects of Nigella sativa supplements on biomarkers of inflammation and oxidative stress: Results from an umbrella meta-analysis.

9. Prostaglandins Other Lipid Mediat. 2025 Jan;176:106945. doi: 10.1016/j.prostaglandins.2024.106945. Epub 2024 Dec 19. Alleviating effects of Nigella sativa supplements on biomarkers of inflammation and oxidative stress: Results from an umbrella meta-analysis. Lan X(1), Xia Y(2). Author inform

Meta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment.

10. Front Pharmacol. 2024 Sep 20;15:1417013. doi: 10.3389/fphar.2024.1417013. eCollection 2024. Meta-analysis of randomized controlled trials assessing the efficacy of nigella sativa supplementation for allergic rhinitis treatment. He Y(#)(1), Hu X(#)(2), Chang L(3), Liu S(4), Lv L(4), Qin G(4),

Comparative Efficacy of Nigella sativa and Chlorhexidine Mouthwashes in the Management of Gingivitis: A Randomized Controlled Trial.

11. J Integr Complement Med. 2026 Mar;32(3):277-283. doi: 10.1177/27683605251406898. Epub 2025 Dec 29. Comparative Efficacy of Nigella sativa and Chlorhexidine Mouthwashes in the Management of Gingivitis: A Randomized Controlled Trial. Arab Farashahi M(1), Vaziri F(1), Ramezani V(2), Moradi S(3)

Nigella sativa Seeds Ease Severity of Premenstrual Syndrome in Women: A Randomized, Double-Blinded, Placebo-Controlled Study.

12. Biomed Res Int. 2025 Nov 19;2025:9811666. doi: 10.1155/bmri/9811666. eCollection 2025. Nigella sativa Seeds Ease Severity of Premenstrual Syndrome in Women: A Randomized, Double-Blinded, Placebo-Controlled Study. Afrin F(1)(2), Neela MM(3), Islam A(4), Islam MR(5), Hossain MM(1). Author inf

Evaluating the cytotoxicity and efficacy of nanoemulsion containing propolis plus Nigella sativa nanoparticles for pulpotomy of primary teeth: randomised split-mouth clinical trial pilot study.

13. Eur Arch Paediatr Dent. 2025 Dec;26(6):1193-1200. doi: 10.1007/s40368-025-01091-w. Epub 2025 Sep 13. Evaluating the cytotoxicity and efficacy of nanoemulsion containing propolis plus Nigella sativa nanoparticles for pulpotomy of primary teeth: randomised split-mouth clinical trial pilot stud

Therapeutic Potential of Thymoquinone in Conjunction with Mechanical Debridement for Peri-Implantitis: A Prospective Clinical Evaluation.

14. J Long Term Eff Med Implants. 2025;35(3):37-43. doi: 10.1615/JLongTermEffMedImplants.2025058363. Therapeutic Potential of Thymoquinone in Conjunction with Mechanical Debridement for Peri-Implantitis: A Prospective Clinical Evaluation. Thanasekaran A(1), Rajasekar A(2). Author information: (

The effect of Nigella Sativa emulgel on episiotomy wound healing and pain intensity in primiparous women: A triple-blind randomized controlled trial.

15. PLoS One. 2025 Jun 4;20(6):e0325112. doi: 10.1371/journal.pone.0325112. eCollection 2025. The effect of Nigella Sativa emulgel on episiotomy wound healing and pain intensity in primiparous women: A triple-blind randomized controlled trial. Maghalian M(1)(2), Alizadeh A(2), Raphi F(3), Islamb

Effect of Nigella sativa seed extract on estradiol, FSH levels, and vaginal maturity index in menopausal women: A randomized controlled trial.

1. Narra J. 2025 Apr;5(1):e1399. doi: 10.52225/narra.v5i1.1399. Epub 2025 Feb 17. Effect of Nigella sativa seed extract on estradiol, FSH levels, and vaginal maturity index in menopausal women: A randomized controlled trial. Sukatendel K(1), Hasibuan RH(2), Siregar MF(3), Faradina D(4), Edianto D

Effect of Nigella sativa-L supplementation on glycemia in adolescent polycystic ovarian syndrome: secondary analysis of a randomized controlled trial study.

47. J Ovarian Res. 2025 Mar 7;18(1):46. doi: 10.1186/s13048-025-01634-1. Effect of Nigella sativa-L supplementation on glycemia in adolescent polycystic ovarian syndrome: secondary analysis of a randomized controlled trial study. Mahmoudian A(1), Ashouri A(2), Mohammadzadeh F(3), Rahmani Bilandi

Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study.

11. Paediatr Drugs. 2025 Jul;27(4):481-489. doi: 10.1007/s40272-025-00687-5. Epub 2025 Mar 6. Cardioprotective Effect of Nigella sativa in Pediatric Patients with Type 1 Diabetes Mellitus: A Randomized Controlled Study. El-Afify D(1), El Amrousy D(2). Author information: (1)Clinical Pharmacy De

Effects of Nigella sativa on disease activity, T lymphocytes and inflammatory cytokine profiles in pediatric systemic lupus erythematosus: A randomized controlled trial.

22. Narra J. 2024 Dec;4(3):e1063. doi: 10.52225/narra.v4i3.1063. Epub 2024 Nov 11. Effects of Nigella sativa on disease activity, T lymphocytes and inflammatory cytokine profiles in pediatric systemic lupus erythematosus: A randomized controlled trial. Barlianto W(1), Wulandari D(1), Sari TL(2),

The Effect of Foot Reflexology and Knee Massage With Black Cumin Seed Oil on Knee Osteoarthritis Symptoms.

34. Holist Nurs Pract. 2026 Jan-Feb 01;40(1):56-65. doi: 10.1097/HNP.0000000000000714. Epub 2025 Nov 11. The Effect of Foot Reflexology and Knee Massage With Black Cumin Seed Oil on Knee Osteoarthritis Symptoms. Bakir E(1), Baglama SS. Author information: (1)Author Affiliations: Department of N

Sun-macerated Hypericum perforatum oleates in fixed oils: analytical characterization and comparative wound-healing activity.

24. Turk J Med Sci. 2026 Feb 4;56(2):570-584. doi: 10.55730/1300-0144.6190. eCollection 2026. Sun-macerated Hypericum perforatum oleates in fixed oils: analytical characterization and comparative wound-healing activity. Çapar C(1), Küpeli E(2), Yaba A(3), Parmaksiz A(4), Sümer E(5), Yeşilada E(1

Novel Cu(OH)(2)/BC: a nano biocomposite for water cleansing.

40. Environ Sci Pollut Res Int. 2026 Apr 27. doi: 10.1007/s11356-026-37753-5. Online ahead of print. Novel Cu(OH)(2)/BC: a nano biocomposite for water cleansing. Munshi GH(1), Al-Balawi AM(2), Al-Malwi SD(3), Al-Mutairi E(3), Alsebaii NM(4), Al-Thubaiti KS(4), Alzahrani EA(5). Author informatio

NP-101 in Combination with Nivolumab and Ipilimumab in Metastatic Extra-pulmonary Neuroendocrine Carcinomas (EP-NECs): A Pilot Study.

43. Endocr Relat Cancer. 2026 Apr 21:ERC-25-0232. doi: 10.1530/ERC-25-0232. Online ahead of print. NP-101 in Combination with Nivolumab and Ipilimumab in Metastatic Extra-pulmonary Neuroendocrine Carcinomas (EP-NECs): A Pilot Study. A M(1), A A(2), M K(3), Mb S(4), B K(5), A D(1), C N(6), M H(7)

High-capacity oxytetracycline sorption using a sustainable microwave-synthesized magnetic CuFe(2)O(4)@carbon nanocomposite from agro-industrial waste.

13. Chemosphere. 2026 Jun;402:144930. doi: 10.1016/j.chemosphere.2026.144930. Epub 2026 Apr 15. High-capacity oxytetracycline sorption using a sustainable microwave-synthesized magnetic CuFe(2)O(4)@carbon nanocomposite from agro-industrial waste. Güzel F(1), Teymur YA(2). Author information: (1

Extraction-Dependent Immunomodulatory and Angiogenesis-Related Molecular Responses of Nigella sativa Oil in Adipose-Derived Mesenchymal Stem Cells.

6. Folia Biol (Praha). 2026;72(1):44-53. doi: 10.14712/fb2026.0004. Extraction-Dependent Immunomodulatory and Angiogenesis-Related Molecular Responses of Nigella sativa Oil in Adipose-Derived Mesenchymal Stem Cells. Ince B(1), Avsar G(2), Turkseven CH(3), Eroglu P(2), Ayar G(1), Akyurek ME(4). A

Characterization of Nigella sativa Meal (NSM) and the Effects on In Vitro Rumen Fermentation and Degradability.

24. Animals (Basel). 2026 Apr 2;16(7):1091. doi: 10.3390/ani16071091. Characterization of Nigella sativa Meal (NSM) and the Effects on In Vitro Rumen Fermentation and Degradability. Juandita KN(1), Ramdani D(2), Hernaman I(3), Chaudhry AS(4), Sukarman(5), Sarwono KA(5). Author information: (1)D

Investigation of Thymoquinone's Effects on Bisphenol A-Induced Neurotoxicity, Keap-1/Nrf-2 Signalling, Oxidative Stress, and Behavior in Rats.

27. J Vis Exp. 2026 Mar 24;(229). doi: 10.3791/70242. Investigation of Thymoquinone's Effects on Bisphenol A-Induced Neurotoxicity, Keap-1/Nrf-2 Signalling, Oxidative Stress, and Behavior in Rats. Kuzay Aksoy D(1), Tozak Yıldız H(2). Author information: (1)Department of Physiology, Faculty of Me

Therapeutic evaluation of phytochemicals present in Nigella sativa seed oil for anxiolytic activity against the GABA-B receptor: a gas chromatography-mass spectrometry (GC-MS)-supported molecular dynamics-based in silico study.

33. In Silico Pharmacol. 2026 Apr 10;14(1):114. doi: 10.1007/s40203-026-00612-9. eCollection 2026. Therapeutic evaluation of phytochemicals present in Nigella sativa seed oil for anxiolytic activity against the GABA-B receptor: a gas chromatography-mass spectrometry (GC-MS)-supported molecular d

Antibiofilm and antibacterial effects of Nigella sativa extract against Streptococcus mutans predicting the role of fatty acids composition: in vitro, CLSM and in silico studies.

26. Biomater Investig Dent. 2026 Jan 28;13:45299. doi: 10.2340/biid.v13.45299. eCollection 2026. Antibiofilm and antibacterial effects of Nigella sativa extract against Streptococcus mutans predicting the role of fatty acids composition: in vitro, CLSM and in silico studies. ELsayed S(1), El-Ad

Enhancement of tobramycin and amikacin activities by co-encapsulation in liposomal-thymoquinone formulation: antibacterial, antibiofilm, and cytocompatibility study.

27. Ther Deliv. 2026 Mar;17(3):217-231. doi: 10.1080/20415990.2026.2653455. Epub 2026 Apr 10. Enhancement of tobramycin and amikacin activities by co-encapsulation in liposomal-thymoquinone formulation: antibacterial, antibiofilm, and cytocompatibility study. Alzahrani RR(1)(2), Alkhulaifi MM(1