벌꿀화분
Bee Pollen
📚 관련 논문 (16편)
1. J Biomater Sci Polym Ed. 2025 Dec;36(18):2837-2858. doi: 10.1080/09205063.2025.2510441. Epub 2025 Jun 2. Nanostructured solid lipid for Paclitaxel and Kaempferol co-delivery as a novel synergistic approach for breast cancer. Dewangan HK(1), Sharma R(1), Marwah H(1), Shah K(2), Alam P(3). Aut
2. Am J Health Syst Pharm. 2010 Dec 1;67(23):2034-7. doi: 10.2146/ajhp090489. Probable interaction between warfarin and bee pollen. Hurren KM(1), Lewis CL. Author information: (1)Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, De
3. Ecotoxicol Environ Saf. 2009 Mar;72(3):931-7. doi: 10.1016/j.ecoenv.2008.06.008. Epub 2008 Aug 15. Evaluation of protective effect of bee pollen against propoxur toxicity in rat. Eraslan G(1), Kanbur M, Silici S, Cem Liman B, Altinordulu S, Soyer Sarica Z. Author information: (1)Faculty of Ve
4. Arch Toxicol. 2026 Feb;100(2):425-436. doi: 10.1007/s00204-025-04218-6. Epub 2025 Oct 10. Pharmacovigilance and toxicological risks associated with apitherapeutic products: a systematic overview. Rocha Filho LKA(1), Silva GI(2), Silva MS(2). Author information: (1)Faculdade de Engenharia de
5. Nutrients. 2023 Feb 25;15(5):1165. doi: 10.3390/nu15051165. The Utilization of Bee Products as a Holistic Approach to Managing Polycystic Ovarian Syndrome-Related Infertility. Ali A(1), Paramanya A(1), Poojari P(1), Arslan-Acaroz D(2)(3), Acaroz U(3)(4)(5), Kostić AŽ(6). Author information:
6. Phytother Res. 2019 Nov;33(11):2938-2947. doi: 10.1002/ptr.6484. Epub 2019 Aug 21. Therapeutic efficacy of orally administered pollen for nonallergic diseases: An umbrella review. Antonelli M(1)(2)(3), Donelli D(1)(2)(4), Firenzuoli F(2). Author information: (1)Terme di Monticelli, Parma, It
7. Food Funct. 2018 Apr 25;9(4):1944-1966. doi: 10.1039/C7FO01792H. Effects of superfoods on risk factors of metabolic syndrome: a systematic review of human intervention trials. van den Driessche JJ(1), Plat J(1), Mensink RP(1). Author information: (1)Department of Nutrition and Movement Scienc
8. J Diet Suppl. 2009;6(3):290-312. doi: 10.1080/19390210903081381. An evidence-based systematic review of bee pollen by the Natural Standard Research Collaboration. Ulbricht C(1), Conquer J, Giese N, Khalsa KP, Sklar J, Weissner W, Woods J. Author information: (1)Massachusetts General Hospital,
1. J Anim Physiol Anim Nutr (Berl). 2019 May;103(3):959-968. doi: 10.1111/jpn.13069. Epub 2019 Feb 4. Bee pollen and propolis as dietary supplements for rabbit: Effect on reproductive performance of does and on immunological response of does and their offspring. Attia YA(1), Bovera F(2), Abd Elhamid AE(3), Nagadi SA(4), Mandour MA(4), Hassan SS(2). Author information: (1)Arid Land Agriculture Department, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia. (2)Department of Veterinary Medicine and Animal Production, University of Napoli Federico II, Napoli, Italy. (3)Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Damanhour, Egypt. (4)Animal Husbandry and Animal Wealth Development Department, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt. Comment in J Anim Physiol Anim Nutr (Berl). 2020 Jan;104(1):399. doi: 10.1111/jpn.13294. To evaluate the effect of bee pollen (BP) and/or propolis (Pro) supplementation on rabbit does, 64 nulliparous NZW rabbits does were distributed among eight groups (eight animals/group). One unsupplemented group was the control; the other seven groups were supplemented, respectively, with zinc bacitracin (ZnB) at 100 mg, BP at 150 and 300 mg, Pro at 150 and 300 mg, BP+Pro at 150 and 300 mg of each three times/week, day after day continuously along eight parities. The BP300, Pro300 and BP+Pro150 groups had higher body weight of litter at birth and number of kids born alive. The BP supplementation at 150 mg increased plasma total protein and albumin than the control group. The BP or Pro at 150 mg decreased plasma T3 than the other groups except for BP+Pro150. The ZnB group had significantly greater T3 /T4 ratio compared to BP, Pro and BP+Pro at 150 mg. The BP+Pro150 group had less ALT than the control; BP300 and Pro 300 mg resulted in lower plasma AST than the groups Pro150 with or without BP and the control group. The plasma alkaline phosphatase of BP at 150 or 300 mg and BP+Pro150 was significantly greater than that of the Pro150 group. The BP+Pro300 group had higher WBCs than the other groups. In contrast, the lymphocytes were greater in the Pro and BP+Pro300 groups than in BP, Pro and BP+Pro at 150 mg. The groups supplemented with BP and BP+Pro at 150 and 300 mg had significantly greater SRBCs of doe rabbits and their offspring compared to the control and the ZnB group. The BP at 300 mg increased the serum albumin and α1 -globulin than the control group. The Pro300 group had greater serum α2 -globulin and β-globulin than the control group. The total globulin was significantly greater for the 300 mg propolis-supplemented groups than the control. © 2019 Blackwell Verlag GmbH. DOI: 10.1111/jpn.13069 PMID: 30714649 [Indexed for MEDLINE]
2. J Anim Physiol Anim Nutr (Berl). 2019 May;103(3):947-958. doi: 10.1111/jpn.13068. Epub 2019 Feb 3. Evaluation of the carryover effect of antibiotic, bee pollen and propolis on growth performance, carcass traits and splenic and hepatic histology of growing rabbits. Attia YA(1), Bovera F(2), Abd-Elhamid AEE(3), Calabrò S(2), Mandour MA(4), Al-Harthi MA(1), Hassan SS(3). Author information: (1)Arid Land Agriculture Department, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia. (2)Department of Veterinary Medicine and Animal Production, University of Napoli Federico II, Napoli, Italy. (3)Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Damanhour, Egypt. (4)Animal Husbandry and Animal Health Development, Faculty of Veterinary Medicine, Alexandria University, Alexandria, Egypt. Sixty-four nulliparous female rabbits were distributed among eight groups (eight animals/group). Group one was the unsupplemented control group; the other seven groups were supplemented with zinc bacitracin (ZnB) at 100 mg, or bee pollen (BP) and/or propolis (Pro) at 150 and 300 mg in a capsulated form, three times a week, day after day, continuously all over the experimental period. The experiment was run for eight parties; at each parity, 28 kids of each doe group (a total of 224 rabbits) were divided into two subgroups weaned, respectively, at 24 and 30 days of age. Thus, for each parity, there were 16 groups (eight does treatments × two weaning age, 14 rabbits per group). The growing rabbits fed the standard diets without supplements. The growth performance, the carcass traits, the liver and the spleen histology of rabbits were checked up to 90 days of age to find possible carryover effects of the supplements. The supplements had no significant effect on most of the growth performance at 90 days of age, but BP150 and BP+Pro300 increased the growth rate in comparison with ZnB group. The liver weight in the control, BP300 and Pro300 groups was higher than the ZnB one. The spleen weight was higher in the groups ZnB, BP150, Pro300 and BP+Pro300, followed by the control, BP300 and BP+Pro150 and thus Pro150. The heart % in the BP150 and Pro300 groups was higher than ZnB and BP+Pro150 groups. A lymphoid hyperplasia of splenic white pulp was observed in the BP+Pro groups, while propolis alone showed a mild activation of lymphobiosis. The Pro and BP groups showed the same picture of the control group exhibiting a hydropic degeneration of mostly hepatic cells, while the ZnB group exhibited adverse effect on the bile ducts featuring portal periductal inflammatory cells infiltration with epithelial hyperplasia reflecting chronic cholangitis. © 2019 Blackwell Verlag GmbH. DOI: 10.1111/jpn.13068 PMID: 30714248 [Indexed for MEDLINE]
3. J Anim Physiol Anim Nutr (Berl). 2014 Feb;98(1):128-39. doi: 10.1111/jpn.12056. Epub 2013 Feb 18. Growth performance, carcass quality, biochemical and haematological traits and immune response of growing rabbits as affected by different growth promoters. Attia YA(1), El-Hanoun AM, Bovera F, Monastra G, El-Tahawy WS, Habiba HI. Author information: (1)Arid Land Agriculture Department, Faculty of Meteorology, Environment and Arid Land Agriculture, King Abdulaziz University, Jeddah, Saudi Arabia; Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Damanhour, Egypt. The aim of the article was to study the effect of different growth promoters on growth performance, carcass quality, biochemical and haematological traits and immune response of growing rabbits. A total number of 105 male growing NZW rabbits during 35-91 days of age were randomly distributed among 7 groups fed the same basal diet and submitted to different dietary treatments: the first group was unsupplemented and used as control; the other groups were supplemented respectively with bee pollen and/or propolis at 200 mg/kg BW of each and inulin and/or mannanoligosaccharides (MOS) at 35 mg/kg BW of each. Body weight gain, daily feed intake, feed conversion ratio (FCR), biochemical and haematological blood parameters, carcass characteristics, histological studies of ileum and spleen and economical efficiency were measured. Bee pollen administered alone or with propolis significantly (p < 0.01) the body weight gain and improved FCR in respect of the control group. Inulin with MOS significantly improved just FCR than the control group. Bee pollen with propolis and MOS supplemented-groups resulted in significantly higher (7.96 and 8.41% respectively) white blood cells compared to the control group. Plasma total cholesterol was significantly higher for the MOS group in respect of the control, bee pollen, inulin and inulin with MOS supplemented-groups. Propolis resulted in significantly higher dressed carcass percentage than the control group and higher carcass index than only bee pollen with propolis supplemented-group. Bee pollen, in particular if in combination with propolis, could be used as a supplement in the growing rabbits during days 35-91 of age with positive effects on growth rate and feed conversion ratio. © 2013 Blackwell Verlag GmbH. DOI: 10.1111/jpn.12056 PMID: 23419029 [Indexed for MEDLINE]
4. J Anim Physiol Anim Nutr (Berl). 2011 Jun;95(3):294-303. doi: 10.1111/j.1439-0396.2010.01054.x. Epub 2010 Sep 29. Effect of bee pollen levels on productive, reproductive and blood traits of NZW rabbits. Attia YA(1), Al-Hanoun A, El-Din AE, Bovera F, Shewika YE. Author information: (1)Department of Animal and Poultry Production, Faculty of Agriculture, Damanhour University, Egypt. yfat_alexu40@hotmail.com Forty New Zealand White (NZW) rabbit does were equally divided among four groups feeding the same commercial diet and receiving a water solution containing, respectively, 0 (control), 100, 200 and 300 mg bee pollen/kg body weight (BW), 1 week before and after mating during moderate (October-February) and hot seasons (May-September) for three consecutive mating in each season. Does were mated with non-treated adult NZW male rabbits 11 days after kindling. Body weight of does, number of service per conception, conception rate, feed intake, litter size, milk production, blood constituents, weight of kits from birth up to weaning and survival rate were determined. For each season, 80 weaned rabbits originated from the does of the control group (untreated does) were equally divided into four groups (0, 100, 200 and 300 mg/kg BW) of bee pollen, given as a water solution twice per week from 4 to 12 weeks of age. The kit of the does given 100, 200 and 300 mg/kg BW did not receive bee pollen during the growing period (4-12 weeks of age). The effect of bee pollen on growing rabbit's performance was studied from 4 to 12 week of age. Bee pollen at 200 mg significantly (p < 0.01) increased body weight of does, conception rate, milk yield, litter size; improved biochemical profiles of blood and helps outstanding of does during both seasons. The same dose of bee pollen significantly increased kit growth and their survival rate until weaning. Growth and feed conversion ratio (FCR) of kits from the treated does during 4-8 weeks of age were significantly better than growth of kits from the untreated does that administrated bee pollen during 4-12 weeks of age. Meanwhile, during the following period (8-12 weeks of age) growth and FCR of kits given bee pollen from the untreated does were significantly better than that of treated does. © 2010 Blackwell Verlag GmbH. DOI: 10.1111/j.1439-0396.2010.01054.x PMID: 20880286 [Indexed for MEDLINE]
5. MedGenMed. 2004 Dec 16;6(4):46. Effects of an herbal medication containing bee products on menopausal symptoms and cardiovascular risk markers: results of a pilot open-uncontrolled trial. Georgiev DB(1), Metka M, Huber JC, Goudev AR, Manassiev N. Author information: (1)Second Obstetrics and Gynecology Hospital, Sofia, Bulgaria. OBJECTIVES: Fifty-five postmenopausal women with menopausal complaints were treated with the food supplement Melbrosia for 3 months. Menopausal symptom evaluation scales and psychological questionnaires were administered, and cardiovascular disease markers in blood were analyzed at the beginning and the end of the trial. SETTING: The perimenopausal care unit of Second Obstetrics and Gynecology Hospital, Sofia, Bulgaria. DESIGN: The study was an open, multicenter, uncontrolled, prospective observation study. The subjective symptoms questionnaires administered before Melbrosia treatment and after 3 months of treatment were Kupperman Score, Zerssen Symptom List, Zung Depression Score, and Frankfurt Self-concept Scale (self-assessment test, problem-solving test, self-esteem test, and irritability test). The blood levels of high-density lipoproteins (HDL), low-density lipoproteins (LDL), triglycerides (TG), total cholesterol (TC), vascular cell adhesion molecule-1 (VCAM-1), and C-reactive protein (CRP) levels were measured in a subgroup of patients. RESULTS: Treatment of postmenopausal women with Melbrosia led to a statistically significant reduction in the Kupperman score, Zerssen's Symptoms List, and Zung Depression Score. The Frankfurt Self-concept Scale revealed significant improvement in problem-solving, no change in self-assessment and self-esteem, and worsening of irritability. Treatment with Melbrosia significantly reduced TC and LDL and significantly elevated HDL and TG. There were nonsignificant changes of serum VCAM-1 and CRP levels in patients treated with Melbrosia. CONCLUSIONS: The presented data suggest that Melbrosia may offer a potential alternative to hormone therapy for the treatment of menopausal symptoms. However, because of this study's uncontrolled, open- label methodology, no cause-and-effect inferences can be drawn until a larger, longer-term, blinded, placebo-controlled, randomized clinical trial is performed. PMCID: PMC1480585 PMID: 15775873 [Indexed for MEDLINE]
6. Animals (Basel). 2023 Jan 27;13(3):439. doi: 10.3390/ani13030439. Effects of Supplementation with Bee Pollen and Propolis on Growth Performance and Serum Metabolites of Rabbits: A Meta-Analysis. Sierra-Galicia MI(1), Rodríguez-de Lara R(1), Orzuna-Orzuna JF(1), Lara-Bueno A(1), Ramírez-Valverde R(1), Fallas-López M(2). Author information: (1)Posgrado en Producción Animal, Departamento de Zootecnia, Universidad Autónoma Chapingo, Texcoco, CP 56230, Mexico. (2)"Conejos" Centro de Investigación Científica del Estado de México A.C. (COCICEMAC), Coatlinchán, CP 56250, Mexico. The objective of this study was to evaluate the effects of bee pollen (BP) and propolis (PRO) supplementation on rabbits' productive performance and serum metabolites through a meta-analysis. Sixteen peer-reviewed publications were included in the data set. The rabbit strains used in the studies included in the data set were New Zealand White, V-line, Rex, and V-line crosses. Weighted mean differences (WMD) between treatments supplemented with BP or PRO and control treatments were used to assess the magnitude of the effect. BP supplementation decreased (p < 0.001) daily feed intake (DFI) and feed conversion ratio (FCR); however, increased (p < 0.001) average daily gain (ADG) and hot carcass yield (HCY). PRO supplementation reduced DFI (p = 0.041) and FCR (p < 0.001), and increased ADG (p < 0.001) and HCY (p = 0.005). In blood serum, BP supplementation increased total antioxidant capacity (TAC; p = 0.002) and decreased serum creatinine concentration (p = 0.049). Likewise, decreased serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and malondialdehyde (MDA) were detected in response to BP supplementation (p < 0.05). PRO supplementation increased the TAC in blood serum (p = 0.018); however, decreased serum concentrations of AST, ALT, and MDA were observed (p < 0.05). In conclusion, BP or PRO supplementation can be used as a natural growth promoter in rabbits, and both can also improve rabbits' antioxidant status. However, BP or PRO supplementation does not affect rabbits' renal or hepatic health status. DOI: 10.3390/ani13030439 PMCID: PMC9913143 PMID: 36766327 Conflict of interest statement: The authors declare no conflict of interest.
7. PLoS Negl Trop Dis. 2022 May 12;16(5):e0010373. doi: 10.1371/journal.pntd.0010373. eCollection 2022 May. Can floral nectars reduce transmission of Leishmania? Palmer-Young EC(1), Schwarz RS(2), Chen Y(1), Evans JD(1). Author information: (1)USDA-ARS Bee Research Laboratory, Beltsville, Maryland, United States of America. (2)Department of Biology, Fort Lewis College, Durango, Colorado, United States of America. BACKGROUND: Insect-vectored Leishmania are responsible for loss of more disability-adjusted life years than any parasite besides malaria. Elucidation of the environmental factors that affect parasite transmission by vectors is essential to develop sustainable methods of parasite control that do not have off-target effects on beneficial insects or environmental health. Many phytochemicals that inhibit growth of sand fly-vectored Leishmania-which have been exhaustively studied in the search for phytochemical-based drugs-are abundant in nectars, which provide sugar-based meals to infected sand flies. PRINCIPLE FINDINGS: In a quantitative meta-analysis, we compare inhibitory phytochemical concentrations for Leishmania to concentrations present in floral nectar and pollen. We show that nectar concentrations of several flowering plant species exceed those that inhibit growth of Leishmania cell cultures, suggesting an unexplored, landscape ecology-based approach to reduce Leishmania transmission. SIGNIFICANCE: If nectar compounds are as effective against parasites in the sand fly gut as predicted from experiments in vitro, strategic planting of antiparasitic phytochemical-rich floral resources or phytochemically enriched baits could reduce Leishmania loads in vectors. Such interventions could provide an environmentally friendly complement to existing means of disease control. DOI: 10.1371/journal.pntd.0010373 PMCID: PMC9098005 PMID: 35551517 [Indexed for MEDLINE] Conflict of interest statement: The authors have declared that no competing interests exist.
8. Complement Ther Med. 2019 Jun;44:235-241. doi: 10.1016/j.ctim.2019.04.017. Epub 2019 Apr 24. Royal jelly does not improve markers of glycemia: A systematic review and meta-analysis of Randomized Clinical Trials. Mahboobi S(1), Jafarnejad S(2), Eftekhari MH(3). Author information: (1)Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran. (2)Research Center for Biochemistry and Nutrition in Metabolic Diseases, Kashan University of Medical Sciences, Kashan, Iran. (3)Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: h_eftekhari@yahoo.com. Bee products including propolis, bee wax, pollen and royal jelly (RJ) have been used as medicine from ancient times. A vast number of in-vivo and in-vitro studies as well as clinical trials have been conducted to investigate potential health related properties of RJ. A growing number of clinical trials have been performed to assess effects of RJ ingestion on different metabolic markers including glycemia, with diverse results. In the current meataanalysis, we aimed to evaluate effects of RJ ingestion on glycemic markers compared with placebo and set directions for future research. Electronic databases including Scopus, Pubmed, Scholar, Cochrane, Proquest, SID and Magiran were searched and 5 eligible studies were included in the quantitative analysis. Review Manager Software was used for statistical analysis and random effects model was used for pooling data. A total of 205 participants for FPG and 130 participants for HbA1c were included. The overall analysis revealed that RJ consumption reduced FPG by 0.95 mg/dl (95% CI: -5.83 to 3.87; p = 0.69; I2 = 0%; Tau2 = 0.00) and HbA1c by 0.32 (95% CI: -0.87 to 0.23; p = 0.25; I2 = 69 %; Tau2 = 0.16) which were not statistically significant. Funnel plot demonstrated no publication bias. In conclusion, RJ supplementation did not beneficially affect markers of glycemia. However, due to methodology issues and potential confounders like diet as well as diverse populations, we recommend future studies well designed and well controlled for major confounders so we can update these data to more precise results and more accurate conclusion. Copyright © 2019 Elsevier Ltd. All rights reserved. DOI: 10.1016/j.ctim.2019.04.017 PMID: 31126561 [Indexed for MEDLINE]
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