사과식초

Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

1. Nutrients. 2025 Sep 19;17(18):3000. doi: 10.3390/nu17183000. Effect of Apple Cider Vinegar Intake on Body Composition in Humans with Type 2 Diabetes and/or Overweight: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Castagna A(1), Ferro Y(1), Noto FR(1), Bruno R(1), Ara

A randomized dietary intervention to increase colonic and peripheral blood SCFAs modulates the blood B- and T-cell compartments in healthy humans.

2. Am J Clin Nutr. 2022 Nov;116(5):1354-1367. doi: 10.1093/ajcn/nqac246. Epub 2023 Feb 10. A randomized dietary intervention to increase colonic and peripheral blood SCFAs modulates the blood B- and T-cell compartments in healthy humans. Gill PA(1), Muir JG(2), Gibson PR(2), van Zelm MC(3). Aut

Apple cider vinegar soaks do not alter the skin bacterial microbiome in atopic dermatitis.

3. PLoS One. 2021 Jun 2;16(6):e0252272. doi: 10.1371/journal.pone.0252272. eCollection 2021. Apple cider vinegar soaks do not alter the skin bacterial microbiome in atopic dermatitis. Luu LA(1), Flowers RH(1), Gao Y(2), Wu M(2), Gasperino S(3), Kellams AL(4), Preston DC(5), Zlotoff BJ(1), Wisni

Synergistic Amelioration of Letrozole-induced Polycystic Ovary Syndrome in Rats: A Therapeutic Approach with Apple Cider Vinegar and Metformin Combination.

4. Reprod Sci. 2024 Sep;31(9):2861-2876. doi: 10.1007/s43032-024-01545-4. Epub 2024 May 22. Synergistic Amelioration of Letrozole-induced Polycystic Ovary Syndrome in Rats: A Therapeutic Approach with Apple Cider Vinegar and Metformin Combination. Danduga RCSR(1), Kurapati AS(2), Shaik RA(2), Ko

Antimicrobial efficacy of natural-based endodontic solutions: a systematic review with a network meta-analysis.

5. Braz Oral Res. 2024 Dec 20;38:e093. doi: 10.1590/1807-3107bor-2024.vol38.0093. eCollection 2024. Antimicrobial efficacy of natural-based endodontic solutions: a systematic review with a network meta-analysis. Ferraz DC(1), Melo AP(1), Matos FS(2), Paranhos LR(3), Moura CCG(4), Blumenberg C(5

The Effects of Apple Cider Vinegar on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Clinical Trials.

6. Curr Med Chem. 2025;32(11):2257-2274. doi: 10.2174/0929867331666230822102021. The Effects of Apple Cider Vinegar on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Clinical Trials. Tehrani SD(1), Keshani M(1), Rouhani MH(2), Moallem SA(3)(4), Bagherniya M(2)(5), Sahebka

Comparative effectiveness of six herbs in the management of glycemic status of type 2 diabetes mellitus patients: A systematic review and network meta-analysis of randomized controlled trials.

7. Diabetes Metab Syndr. 2023 Aug;17(8):102826. doi: 10.1016/j.dsx.2023.102826. Epub 2023 Jul 7. Comparative effectiveness of six herbs in the management of glycemic status of type 2 diabetes mellitus patients: A systematic review and network meta-analysis of randomized controlled trials. Kumar

The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials.

8. BMC Complement Med Ther. 2021 Jun 29;21(1):179. doi: 10.1186/s12906-021-03351-w. The effect of apple cider vinegar on lipid profiles and glycemic parameters: a systematic review and meta-analysis of randomized clinical trials. Hadi A(1), Pourmasoumi M(2), Najafgholizadeh A(3), Clark CCT(4), Es

Study on the Impact of Herbal Shampoo with Gharaghorot, Vinegar, and Ajwain against Head Lice.

1. J Arthropod Borne Dis. 2025 Mar 31;19(1):1-11. doi: 10.18502/jad.v19i1.19991. eCollection 2025 Mar. Study on the Impact of Herbal Shampoo with Gharaghorot, Vinegar, and Ajwain against Head Lice. Akhoundi-Meybodi Z(1), Khesadeh R(1), Zare-Zardini H(2). Author information: (1)Department of Infectious Diseases, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. (2)Department of Biomedical Engineering, Meybod University, Meybod, Iran. BACKGROUND: This study evaluates a herbal shampoo containing Gharaghorot, vinegar, and Ajwain for managing head lice, particularly in resource-limited settings. METHODS: The herbal shampoo formulation constituted 100% final solution, composed of: 28.85% Gharaghorot extract (prepared from sour yogurt juice), 67.31% apple cider vinegar, 2.88% Ajwain (Trachyspermum ammi) essential oil, and 0.96% xanthan gum (a biocompatible thickening agent). Cell toxicity and sterility were assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and fluid thioglycollate and soybean casein digest media, respectively. Irritation and sensitization tests were conducted on rabbits and guinea pigs, respectively. A randomized controlled trial with 114 patients compared the herbal shampoo to standard Permethrin treatment (Permethrin shampoo 1%). Participants applied the shampoo daily for one hour over seven days, with efficacy evaluated by counting live lice and nits before treatment, three days in, and seven days post-treatment. RESULTS: The herbal shampoo exhibited no significant cytotoxicity at concentrations of 10% or lower. The shampoo did not cause sensitization, edema, or erythema. Microbial contamination analysis showed no detectable levels of aerobic or anaerobic bacteria or fungal spores. In the human study, the intervention group showed a 0% prevalence of live lice by the seventh day, compared to 50% in the permethrin group (P= 0.021), and a significant reduction in lice eggs to 42% versus 100% in the permethrin group (P= 0.025). CONCLUSION: The herbal shampoo demonstrated safety, microbiological purity, and notable efficacy in reducing live head lice and partial effectiveness against nits (42% egg viability post-treatment). Copyright© 2025 The Authors. Published by Tehran University of Medical Sciences. DOI: 10.18502/jad.v19i1.19991 PMCID: PMC12630050 PMID: 41278183

Apple cider vinegar administration on carcass characteristics and meat quality of broiler chickens.

2. Trop Anim Health Prod. 2021 Nov 3;53(6):530. doi: 10.1007/s11250-021-02967-x. Apple cider vinegar administration on carcass characteristics and meat quality of broiler chickens. Adeleye OO(1), Abatan MO(2), Dosumu OA(3), James AS(3), Adegoke AV(2), Mamidu MO(2), Sodipe OG(4), Olorunsogbon BF(5), Sanwo KA(2). Author information: (1)Department of Animal Production and Health, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria. adeleyeoo@funaab.edu.ng. (2)Department of Animal Production and Health, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria. (3)Department of Biochemistry, Federal University of Agriculture, Abeokuta, Ogun State, Nigeria. (4)Department of Animal and Environmental Biology, Federal University Oye-Ekiti, Oye-Ekiti, Ekiti State, Nigeria. (5)Department of Agricultural Technology, Federal Polytechnic Ilaro, Ilaro, Ogun state, Nigeria. This study evaluated the effect of apple cider vinegar (ACV) on the carcass characteristics and meat quality of broiler chickens. A total of 300 broilers (Arbor Acre) were randomized to six treatments replicated 5 times (50 birds/treatment and 10 birds/replicate) from 2 days old till the sixth week of age in a 2 by 3 factorial layout consisting of dosages (5.0 mL/L and 10.0 mL/L ACV) and administration frequency (antibiotics following standard schedule, twice/week ACV and thrice/week ACV). At the sixth week, sixty birds (10 birds/treatment) were selected for carcass yield, cut part yield, organ weight, meat technological properties, lipid profiles, and malondialdehyde (MDA) level evaluation. Data obtained were subjected to two-way ANOVA followed by Tukey's test at a P < 0.05 significant level. Birds administered 5.0 mL/L ACV thrice weekly presented a significantly (P < 0.05) higher plucked, eviscerated, dressed, thigh and breast weight compared with the other treatments. The spleen of birds in the control group was significantly (P < 0.05) heavier than those administered ACV. The meat from the 5.0 mL/L ACV group had significantly higher (P < 0.05) water absorptive power and lower refrigeration loss, as depicted in the main effect table. Meat cholesterol, phospholipids, and MDA levels did not differ across the treatments except triglyceride, which was significantly (P < 0.05) lower in the 5.0 mL/L ACV thrice-weekly group. This study concludes that ACV administration could improve carcass yield and meat quality indices. Thus, its use as an alternative to conventional antibiotics for broiler chickens might be beneficial. © 2021. The Author(s), under exclusive licence to Springer Nature B.V. DOI: 10.1007/s11250-021-02967-x PMID: 34731308 [Indexed for MEDLINE]

Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal.

3. J Diet Suppl. 2015 Jun;12(2):138-45. doi: 10.3109/19390211.2014.950783. Epub 2014 Aug 21. Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal. Brown R(1), Sam CH, Green T, Wood S. Author information: (1)1Department of Human Nutrition, University of Otago, Dunedin, New Zealand. Chewing gum alleviates symptoms of gastro-esophageal reflux (GER) following a refluxogenic meal. GutsyGum(tm), a chewing gum developed to alleviate the symptoms of GER contains calcium carbonate, with a proprietary blend of licorice extract, papain, and apple cider vinegar (GiGs®). The efficacy of GutsyGum(tm) was determined in alleviating the symptoms of GER after a refluxogenic meal compared to placebo gum. This double-blind, placebo-controlled-crossover trial with a one-week washout between treatments had 24 participants with a history of GER consume a refluxogenic meal and then chew GutsyGum(tm) or placebo gum. Participants completed GER symptom questionnaires, consisting of symptom based 10 cm Visual Analogue Scales, immediately following the meal and then at regular intervals out to four hours postmeal. Adjusted mean ± SEM heartburn score (15-min postmeal to 240 min) was significantly lower in GutsyGum(tm) than in placebo gum treatment (0.81 ± 0.20 vs. 1.45 ± 0.20 cm; p = 0.034). Mean acid reflux score was significantly lower in GutsyGum(tm) than in placebo treatment (0.72 ± 0.19 vs. 1.46 ± 0.19 cm; p = 0.013). There were no significant differences for any of the secondary outcomes. However, pain approached significance with less pain reported in GutsyGum(tm) versus placebo treatment (0.4 ± 0.2 vs. 0.9 ± 0.2 cm; p = 0.081). Although nausea (p = 0.114) and belching (p = 0.154) were lower following GutsyGum(tm), the difference was not statistically significant. GutsyGum(tm) is more effective than a placebo gum in alleviating primary symptoms of heartburn and acid reflux (Clinical Trial Registration: ACTRN12612000973819). DOI: 10.3109/19390211.2014.950783 PMID: 25144853 [Indexed for MEDLINE]